Search Results - "Paulet, Pierre"

Estrogen receptor α signaling in T lymphocytes is required for estradiol-mediated inhibition of Th1 and Th17 cell differentiation and protection against experimental autoimmune encephalomyelitis by Lélu, Karine, Laffont, Sophie, Delpy, Laurent, Paulet, Pierre-Emmanuel, Périnat, Therese, Tschanz, Stefan A, Pelletier, Lucette, Engelhardt, Britta, Guéry, Jean-Charles

“…Estrogen treatment exerts a protective effect on experimental autoimmune encephalomyelitis (EAE) and is under clinical trial for multiple sclerosis therapy…”
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Protein kinase C–dependent activation of CaV1.2 channels selectively controls human TH2-lymphocyte functions by Robert, Virginie, Triffaux, Emily, Paulet, Pierre-Emmanuel, Guéry, Jean-Charles, Pelletier, Lucette, Savignac, Magali

“…In addition to calcium release–activated calcium channel/ORAI calcium channels, the role of voltage-gated calcium (Cav1) channels in T-cell calcium signaling…”
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Circulating follicular helper T cells exhibit reduced ICOS expression and impaired function in narcolepsy type 1 patients by Nguyen, Xuan-Hung, Dauvilliers, Yves, Quériault, Clémence, Perals, Corine, Romieu-Mourez, Raphaelle, Paulet, Pierre-Emmanuel, Bernard-Valnet, Raphaël, Fazilleau, Nicolas, Liblau, Roland

“…Despite genetic and epidemiological evidence strongly supporting an autoimmune basis for narcolepsy type 1, the mechanisms involved have remained largely…”
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Knocking Down Cav1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma by CABRAL, Marilena Djata, PAULET, Pierre-Emmanuel, MAGNAN, Antoine, YSSEL, Hans, MARIAME, Bernard, GUERY, Jean-Charles, PELLETIER, Lucette, ROBERT, Virginie, GOMES, Bruno, RENOUD, Marie-Laure, SAVIGNAC, Magali, LECLERC, Catherine, MOREAU, Marc, LAIR, David, LANGELOT, Marie

“…Th2 cells orchestrate allergic asthma and the cytokines they produce (IL-4, IL-5, and IL-13) are deleterious in allergy. Therefore, it is important to identify…”
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Impaired NFAT Transcriptional Activity in Antigen-Stimulated CD8 T Cells Linked to Defective Phosphorylation of NFAT Transactivation Domain by Leung-Theung-Long, Stephane, Mondor, Isabelle, Guiraud, Martine, Lamare, Camille, Nageleekar, Viswas, Paulet, Pierre-Emmanuel, Rincon, Mercedes, Guerder, Sylvie

“…NFAT transcription factors play critical roles in CD4 T cell activation and differentiation. Their function in CD8 T cell is, however, unknown. We show in this…”
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The cGMP/Protein Kinase G Pathway Contributes to Dihydropyridine-sensitive Calcium Response and Cytokine Production in TH2 Lymphocytes by Gomes, Bruno, Savignac, Magali, Cabral, Marilena Djata, Paulet, Pierre, Moreau, Marc, Leclerc, Catherine, Feil, Robert, Hofmann, Franz, Guéry, Jean-Charles, Dietrich, Gilles, Pelletier, Lucette

“…Th2 lymphocytes differ from other CD4+ T lymphocytes not only by their effector tasks but also by their T cell receptor (TCR)-dependent signaling pathways. We…”
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Mannose Receptor Ligand-Positive Cells Express the Metalloprotease Decysin in the B Cell Follicle by Mueller, Chris G. F, Cremer, Isabelle, Paulet, Pierre E, Niida, Shumpei, Maeda, Norihiko, Lebeque, Serge, Fridman, Wolf H, Sautes-Fridman, Catherine

“…Decysin, a gene encoding a disintegrin metalloprotease, is transcribed in human dendritic cells (DC) and germinal centers (GC). We have cloned its murine…”
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"Normes et politiques du Conseil de l'Europe en matière d'accès au droit", Le Dossier : De l'accès au droit à l'exercice de la citoyenneté, Actes du colloque de Clermont-Ferrand des 24-25 septembre 2015, textes réunis par F. Faberon et A. Habrial, La Revue du Centre Michel de l'Hospital [ édition électronique ], 2017, n° 12, pp. 65-73 by Paulet, Pierre-Henri

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Cutting Edge: T Lymphocyte Activation by Repeated Immunological Synapse Formation and Intermittent Signaling by Faroudi, Mustapha, Zaru, Rossana, Paulet, Pierre, Muller, Sabina, Valitutti, Salvatore

“…The activation of biological T cell responses requires prolonged contact with APCs and sustained signaling. We investigated whether signaling must be…”
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Protein kinase C–dependent activation of CaV 1.2 channels selectively controls human TH 2-lymphocyte functions by Robert, Virginie, PhD, Triffaux, Emily, PhD, Paulet, Pierre-Emmanuel, BSc, Guéry, Jean-Charles, PhD, Pelletier, Lucette, MD, PhD, Savignac, Magali, PhD

“…Background In addition to calcium release–activated calcium channel/ORAI calcium channels, the role of voltage-gated calcium (Cav 1) channels in T-cell calcium…”
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Calcium Channel Blocker Prevents T Helper Type 2 Cell-mediated Airway Inflammation by Gomes, Bruno, Cabral, Marilena Djata, Gallard, Alexandra, Savignac, Magali, Paulet, Pierre, Druet, Philippe, Mariame, Bernard, Moreau, Marc, Leclerc, Catherine, Guery, Jean-Charles, Pelletier, Lucette

“…Ca(2+) signaling controls the production of T helper (Th) type 2 cytokines known to be deleterious in asthma. Recently, we showed that Ca(2+) signaling was…”
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Dossier : "A qui profite le droit ?", Actes du colloque de Clermont-Ferrand du 26 mars 2015, textes réunis par F. Brunel, I. Guilhen, D. Huet et P-H. Paulet, La Revue du Centre Michel de L'Hospital [En ligne], J-B. Perrier (dir.), n° 11, 2017, pp. 6-123 by Brunel, Fanny, Guilhen, Isabelle, Huet, Davy, Paulet, Pierre-Henri

“…La contestation du droit, par Lamia EL BADAWI, Maître de conférences en droit privé, CMH EA 4232, Université Clermont Auvergne ;REQUISITOIRE CONTRE LE DROIT :…”
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Knocking Down Ca^sub v^1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma by Cabral, Marilena Djata, Paulet, Pierre-Emmanuel, Robert, Virginie, Gomes, Bruno, Renoud, Marie-Laure, Savignac, Magali, Leclerc, Catherine, Moreau, Marc, Lair, David, Langelot, Marie, Magnan, Antoine, Yssel, Hans, Mariamé, Bernard, Guéry, Jean-Charles, Pelletier, Lucette

“…Th2 cells orchestrate allergic asthma and the cytokines they produce (IL-4, IL-5, and IL-13) are deleterious in allergy. Therefore, it is important to identify…”
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Knocking Down Ca v 1 Calcium Channels Implicated in Th2 Cell Activation Prevents Experimental Asthma by Cabral, Marilena Djata, Paulet, Pierre-Emmanuel, Robert, Virginie, Gomes, Bruno, Renoud, Marie-Laure, Savignac, Magali, Leclerc, Catherine, Moreau, Marc, Lair, David, Langelot, Marie, Magnan, Antoine, Yssel, Hans, Mariamé, Bernard, Guéry, Jean-Charles, Pelletier, Lucette

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Dihydropyridine Receptors Are Selective Markers of Th2 Cells and Can Be Targeted to Prevent Th2-Dependent Immunopathological Disorders by Savignac, Magali, Gomes, Bruno, Gallard, Alexandra, Narbonnet, Stephane, Moreau, Marc, Leclerc, Catherine, Paulet, Pierre, Mariame, Bernard, Druet, Philippe, Saoudi, Abdelhadi, Fournie, Gilbert J, Guery, Jean-Charles, Pelletier, Lucette

“…Th1 cells that produce IFN-gamma are essential in the elimination of intracellular pathogens, and Th2 cells that synthetize IL-4 control the eradication of…”
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Protein kinase C‐mediated calcium entry dependent upon dihydropyridine‐sensitive channels: a T‐cell receptor‐coupled signaling pathway involved in interleukin 4 synthesis by Savignac, Magali, Badou, Abdallah, Moreau, Marc, Leclerc, Catherine, Guéry, Jean-Charles, Paulet, Pierre, Druet, Philippe, Ragab-Thomas, Jeannie, Pelletier, Lucette

“…ABSTRACT Signaling events induced by T‐cell receptor (TCR) engagement involve a cascade of tyrosine phosphorylation events leading to activation of several…”
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OR.26. Blocking Cav1-Related Dihydropyridine Receptors Prevents Experimental Allergic Asthma Through Inhibition of Th2 Effector Functions by Gomes, Bruno, Djata Cabral, Marilena, Paulet, Pierre, Guery, Jean-Charles, Pelletier, Lucette

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Protein kinase C-mediated calcium entry dependent upon dihydropyridine sensitive channels: a T cell receptor-coupled signaling pathway involved in IL-4 synthesis by Savignac, M, Badou, A, Moreau, M, Leclerc, C, Guéry, J C, Paulet, P, Druet, P, Ragab-Thomas, J, Pelletier, L

“…CD4+T helper (Th) cells include effector Th1 cells, which produce interleukin 2 (IL-2) and interferon gamma (IFN- gamma ), and IL-4-producing Th2 ceIls; these…”
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Weak TCR stimulation induces a calcium signal that triggers IL‐4 synthesis, stronger TCR stimulation induces MAP kinases that control IFN‐γ  production by Badou, Abdallah, Savignac, Magali, Moreau, Marc, Leclerc, Catherine, Foucras, Gilles, Cassar, George, Paulet, Pierre, Lagrange, Dominique, Druet, Philippe, Guéry, Jean‐Charles, Pelletier, Lucette

“…Th1 and Th2 cells produce different cytokines and have distinct functions. Th1/Th2 cell differentiation is influenced, among other factors, by the nature of…”
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Gold is a T cell polyclonal activator in BN and LEW rats but favors IL‐4 expression only in autoimmune prone BN rats by Savignac, Magali, Badou, Abdallah, Delmas, Christelle, Subra, Jean‐François, Cramer, Stéphane De, Paulet, Pierre, Cassar, Georges, Druet, Philippe, Saoudi, Abdelhadi, Pelletier, Lucette

“…Gold salts are beneficial in the treatment of rheumatoid arthritis but may induce immune‐mediated disorders in predisposed patients. Gold salts induce…”
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