Search Results - "Paula Goetting‐Minesky, M."
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Enhanced transformation efficiency in Treponema denticola enabled by SyngenicDNA-based plasmids lacking restriction-modification target motifs
Published in Molecular oral microbiology (01-12-2023)“…Oral spirochetes are among a small group of keystone pathogens contributing to dysregulation of tissue homeostatic processes that leads to breakdown of the…”
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1,2‐Diacylglycerol choline phosphotransferase catalyzes the final step in the unique Treponema denticola phosphatidylcholine biosynthesis pathway
Published in Molecular microbiology (01-03-2017)“…Summary Treponema denticola synthesizes phosphatidylcholine through a licCA‐dependent CDP‐choline pathway identified only in the genus Treponema. However, the…”
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Composition and Localization of Treponema denticola Outer Membrane Complexes
Published in Infection and Immunity (01-12-2011)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Immunotopological Analysis of the Treponema denticola Major Surface Protein (Msp)
Published in Journal of bacteriology (15-01-2019)“…, one of several recognized periodontal pathogens, is a model organism for studying physiology and host-microbe interactions. Its major surface protein Msp (or…”
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Approaches to Understanding Mechanisms of Dentilisin Protease Complex Expression in Treponema denticola
Published in Frontiers in cellular and infection microbiology (18-05-2021)“…The oral spirochete Treponema denticola is a keystone periodontal pathogen that, in association with members of a complex polymicrobial oral biofilm,…”
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Evolutionary Genomics of Inversions in Drosophila pseudoobscura: Evidence for Epistasis
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2003)“…Drosophila pseudoobscura harbors a rich polymorphism for paracentric inversions on the third chromosome, and the clines in the inversion frequencies across the…”
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Purification of Native Dentilisin Complex from Treponema denticola by Preparative Continuous Polyacrylamide Gel Electrophoresis and Functional Analysis by Gelatin Zymography
Published in Bio-protocol (05-04-2024)“…Periodontal disease is characterized by the destruction of the hard and soft tissues comprising the periodontium. This destruction translates to a degradation…”
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A simplified erythromycin resistance cassette for Treponema denticola mutagenesis
Published in Journal of microbiological methods (01-10-2010)“…The primary selectable marker for the genetic studies of Treponema denticola is a hybrid gene cassette containing both ermF and ermAM (ermB) genes. ErmB…”
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Treponema denticola PrcB Is Required for Expression and Activity of the PrcA-PrtP (Dentilisin) Complex
Published in Journal of Bacteriology (01-07-2010)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Mammalian male mutation bias: impacts of generation time and regional variation in substitution rates
Published in Journal of molecular evolution (01-10-2006)“…In mammals, males undergo a greater number of germline cell divisions compared with females. Thus, the male germline accumulates more DNA replication errors,…”
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Characterization of Treponema denticola Major Surface Protein (Msp) by Deletion Analysis and Advanced Molecular Modeling
Published in Journal of bacteriology (20-09-2022)“…Treponema denticola, a keystone pathogen in periodontitis, is a model organism for studying Treponema physiology and host-microbe interactions. Its major…”
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Development of a small shuttle plasmid for use in oral Veillonella and initial appraisal of potential for fluorescence-based applications
Published in Letters in applied microbiology (05-08-2024)“…Oral Veillonella species are among the early colonizers of the human oral cavity. We constructed a small, single-selectable-marker shuttle plasmid, examined…”
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Roles of TroA and TroR in Metalloregulated Growth and Gene Expression in Treponema denticola
Published in Journal of bacteriology (11-03-2020)“…The availability of divalent metal cations required as cofactors for microbial metabolism is severely limited in the host environment. Bacteria have evolved…”
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A Modified Shuttle Plasmid Facilitates Expression of a Flavin Mononucleotide-Based Fluorescent Protein in Treponema denticola ATCC 35405
Published in Applied and environmental microbiology (01-09-2015)“…Oral pathogens, including Treponema denticola, initiate the dysregulation of tissue homeostasis that characterizes periodontitis. However, progress of research…”
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Seven cDNAs enriched following hippocampal lesion: possible roles in neuronal responses to injury
Published in Brain research. Molecular brain research. (10-09-2003)“…Synaptic plasticity is important for formation of long-term memories and in re-establishment of function following injury. Seven cDNAs enriched following…”
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Identification of the primary mechanism of complement evasion by the periodontal pathogen, Treponema denticola
Published in Molecular oral microbiology (01-04-2011)“…Summary Treponema denticola, a periodontal pathogen, binds the complement regulatory protein Factor H (FH). Factor H binding protein B (FhbB) is the sole FH…”
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Conservation and revised annotation of the Treponema denticola prcB-prcA-prtP locus encoding the dentilisin (CTLP) protease complex
Published in Molecular oral microbiology (01-06-2013)“…Summary Interstrain differences in antigenic surface proteins may reflect immunological pressure or differences in receptor specificity of the antigen…”
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