Search Results - "Paula, Ruth B"

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin by Bacolla, Albino, Sengupta, Shiladitya, Ye, Zu, Yang, Chunying, Mitra, Joy, De-Paula, Ruth B, Hegde, Muralidhar L, Ahmed, Zamal, Mort, Matthew, Cooper, David N, Mitra, Sankar, Tainer, John A

“…Abstract Human genome stability requires efficient repair of oxidized bases, which is initiated via damage recognition and excision by NEIL1 and other base…”
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Functional screening of lysosomal storage disorder genes identifies modifiers of alpha-synuclein neurotoxicity by Yu, Meigen, Ye, Hui, De-Paula, Ruth B, Mangleburg, Carl Grant, Wu, Timothy, Lee, Tom V, Li, Yarong, Duong, Duc, Phillips, Bridget, Cruchaga, Carlos, Allen, Genevera I, Seyfried, Nicholas T, Al-Ramahi, Ismael, Botas, Juan, Shulman, Joshua M

“…Heterozygous variants in the glucocerebrosidase (GBA) gene are common and potent risk factors for Parkinson's disease (PD). GBA also causes the autosomal…”
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Translesion polymerase eta both facilitates DNA replication and promotes increased human genetic variation at common fragile sites by Twayana, Shyam, Bacolla, Albino, Barreto-Galvez, Angelica, De-Paula, Ruth B., Drosopoulos, William C., Kosiyatrakul, Settapong T., Bouhassira, Eric E., Tainer, John A., Madiredd, Advaitha, Schildkraut, Carl L.

“…Common fragile sites (CFSs) are difficult-to-replicate genomic regions that form gaps and breaks on metaphase chromosomes under replication stress. They are…”
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Blood-stage Plasmodium vivax antibody dynamics in a low transmission setting: A nine year follow-up study in the Amazon region by Pires, Camilla V, Alves, Jessica R S, Lima, Barbara A S, Paula, Ruth B, Costa, Helena L, Torres, Leticia M, Sousa, Taís N, Soares, Irene S, Sanchez, Bruno A M, Fontes, Cor J F, Ntumngia, Francis B, Adams, John H, Kano, Flora S, Carvalho, Luzia H

“…Plasmodium vivax remains a global health problem and its ability to cause relapses and subpatent infections challenge control and elimination strategies. Even…”
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Global Characterization of Fungal Mitogenomes: New Insights on Genomic Diversity and Dynamism of Coding Genes and Accessory Elements by Fonseca, Paula L C, De-Paula, Ruth B, Araújo, Daniel S, Tomé, Luiz Marcelo Ribeiro, Mendes-Pereira, Thairine, Rodrigues, Wenderson Felipe Costa, Del-Bem, Luiz-Eduardo, Aguiar, Eric R G R, Góes-Neto, Aristóteles

“…Fungi comprise a great diversity of species with distinct ecological functions and lifestyles. Similar to other eukaryotes, fungi rely on interactions with…”
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Exploring the Relationship Among Divergence Time and Coding and Non-coding Elements in the Shaping of Fungal Mitochondrial Genomes by Fonseca, Paula L C, Badotti, Fernanda, De-Paula, Ruth B, Araújo, Daniel S, Bortolini, Dener E, Del-Bem, Luiz-Eduardo, Azevedo, Vasco A, Brenig, Bertram, Aguiar, Eric R G R, Góes-Neto, Aristóteles

“…The order Hypocreales (Ascomycota) is composed of ubiquitous and ecologically diverse fungi such as saprobes, biotrophs, and pathogens. Despite their…”
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Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation by De-Paula, Ruth B., Bacolla, Albino, Syed, Aleem, Tainer, John A.

“…Non-B DNA G-quadruplex (G4) structures with guanine (G) runs of 2 to 4 repeats can trigger opposing experimental transcriptional impacts. Here, we used…”
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Alzheimer’s disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity by Pavešković, Matea, De-Paula, Ruth B, Ojelade, Shamsideen A, Tantry, Evelyne K, Kochukov, Mikhail Y, Bao, Suyang, Veeraragavan, Surabi, Garza, Alexandra R, Srivastava, Snigdha, Song, Si-Yuan, Fujita, Masashi, Duong, Duc M, Bennett, David A, De Jager, Philip L, Seyfried, Nicholas T, Dickinson, Mary E, Heaney, Jason D, Arenkiel, Benjamin R, Shulman, Joshua M

“…Abstract CD2-Associated protein (CD2AP) is a candidate susceptibility gene for Alzheimer’s disease, but its role in the mammalian central nervous system…”
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Phylogenomics and gene selection in Aspergillus welwitschiae: Possible implications in the pathogenicity in Agave sisalana by Quintanilha-Peixoto, Gabriel, Marone, Marina Püpke, Raya, Fábio Trigo, José, Juliana, Oliveira, Adriele, Fonseca, Paula Luize Camargos, Tomé, Luiz Marcelo Ribeiro, Bortolini, Dener Eduardo, Kato, Rodrigo Bentes, Araújo, Daniel S., De-Paula, Ruth B., Cuesta-Astroz, Yesid, Duarte, Elizabeth A.A., Badotti, Fernanda, de Carvalho Azevedo, Vasco Ariston, Brenig, Bertram, Soares, Ana Cristina Fermino, Carazzolle, Marcelo Falsarella, Pereira, Gonçalo Amarante Guimarães, Aguiar, Eric Roberto Guimarães Rocha, Góes-Neto, Aristóteles

“…Aspergillus welwitschiae causes bole rot disease in sisal (Agave sisalana and related species) which affects the production of natural fibers in Brazil, the…”
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Comparative mitogenomics of Agaricomycetes: Diversity, abundance, impact and coding potential of putative open-reading frames by Araújo, Daniel S., De-Paula, Ruth B., Tomé, Luiz M.R., Quintanilha-Peixoto, Gabriel, Salvador-Montoya, Carlos A., Del-Bem, Luiz-Eduardo, Badotti, Fernanda, Azevedo, Vasco A.C., Brenig, Bertram, Aguiar, Eric R.G.R., Drechsler-Santos, Elisandro R., Fonseca, Paula L.C., Góes-Neto, Aristóteles

“…[Display omitted] •Sequenced mitogenomes of the species Phellinotus piptadeniae and Trametes villosa.•Variation in mtDNA size is due to non-coding regions,…”
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