Search Results - "Paula, Eneida de"
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Exosomes in the serum of Acute Myeloid Leukemia patients induce dendritic cell tolerance: Implications for immunotherapy
Published in Vaccine (07-03-2019)“…Exosomes may represent an interesting antigenic pulse for new forms of anti-tumor immunotherapy. We evaluated exosomes from serum of patients with acute…”
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A pre-formulation study of tetracaine loaded in optimized nanostructured lipid carriers
Published in Scientific reports (02-11-2021)“…Tetracaine (TTC) is a local anesthetic broadly used for topical and spinal blockade, despite its systemic toxicity. Encapsulation in nanostructured lipid…”
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Excipient-excipient interactions in the development of nanocarriers: an innovative statistical approach for formulation decisions
Published in Scientific reports (24-07-2019)“…Excipient interaction has become essential knowledge for rational formulation design of nanoparticles. Nanostructured lipid carriers (NLCs) include at least…”
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Capsaicin-Cyclodextrin Complex Enhances Mepivacaine Targeting and Improves Local Anesthesia in Inflamed Tissues
Published in International journal of molecular sciences (10-08-2020)“…Acidic environments, such as in inflamed tissues, favor the charged form of local anesthetics (LA). Hence, these drugs show less cell permeation and diminished…”
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5
Hybrid nanofilms as topical anesthetics for pain-free procedures in dentistry
Published in Scientific reports (09-07-2020)“…Topical anesthetics are widely applied in order to relieve the discomfort and anxiety caused by needle insertion and other painful superficial interventions at…”
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Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia
Published in PloS one (14-09-2016)“…To develop an anesthetic mucoadhesive film containing Acmella oleracea (jambu) extract for topical use on oral mucosa. Ethanolic extracts from aerial parts of…”
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Direct Visualization of the Action of Triton X-100 on Giant Vesicles of Erythrocyte Membrane Lipids
Published in Biophysical journal (03-06-2014)“…The raft hypothesis proposes that microdomains enriched in sphingolipids, cholesterol, and specific proteins are transiently formed to accomplish important…”
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Methylene blue associated with maghemite nanoparticles has antitumor activity in breast and ovarian carcinoma cell lines
Published in Cancer nanotechnology (01-12-2021)“…Background Cancer constitutes group of diseases responsible for the second largest cause of global death, and it is currently considered one of the main public…”
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Bupivacaine in alginate and chitosan nanoparticles: an in vivo evaluation of efficacy, pharmacokinetics, and local toxicity
Published in Journal of pain research (01-01-2018)“…This study reports a preclinical evaluation of an alginate/chitosan nanoparticle formulation containing NovaBupi®, a racemic bupivacaine (BVC) containing 25%…”
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10
Extracellular vesicles in infectious diseases caused by protozoan parasites in buffaloes
Published in The journal of venomous animals and toxins including tropical diseases (2020)“…Extracellular vesicles (EVs) are small membrane-bound vesicles of growing interest in vetetinary parasitology. The aim of the present report was to provide the…”
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Use of nanoparticle concentration as a tool to understand the structural properties of colloids
Published in Scientific reports (17-01-2018)“…Elucidation of the structural properties of colloids is paramount for a successful formulation. However, the intrinsic dynamism of colloidal systems makes…”
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12
Fusogenic Liposomes Increase the Antimicrobial Activity of Vancomycin Against Staphylococcus aureus Biofilm
Published in Frontiers in pharmacology (29-11-2019)“…The aim of the present study was to encapsulate vancomycin in different liposomal formulations and compare the antimicrobial activity against biofilms. Large…”
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13
Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration
Published in Scientific reports (01-08-2019)“…Inflammatory conditions of the temporomandibular joint (TMJ) and peripheral tissues affect many people around the world and are commonly treated with…”
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14
Hybrid Hydrogel Composed of Polymeric Nanocapsules Co-Loading Lidocaine and Prilocaine for Topical Intraoral Anesthesia
Published in Scientific reports (19-12-2018)“…This study reports the development of nanostructured hydrogels for the sustained release of the eutectic mixture of lidocaine and prilocaine (both at 2.5%) for…”
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Hydroxyapatite-coated liposomes for the controlled release of quantum dots and bupivacaine
Published in Journal of materials research (28-07-2021)“…This work reports the development of hydroxyapatite-coated liposomes to encapsulate drug bupivacaine and quantum dots (CdSe) to be used as a theranostic tool…”
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Factorial Design and Development of Solid Lipid Nanoparticles (SLN) for Gene Delivery
Published in Journal of nanoscience and nanotechnology (01-02-2015)“…Several scientific hurdles still have to be overcome before gene therapy becomes a reality. One of them is the development of safe and efficient gene delivery…”
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Liposomal encapsulation improves the duration of soft tissue anesthesia but does not induce pulpal anesthesia
Published in Journal of clinical anesthesia (01-08-2010)“…Abstract Study Objective To compare the topical and the pulpal anesthesia efficacy of liposomal and plain benzocaine formulations. Design Double-blinded,…”
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Docetaxel Loaded in Copaiba Oil-Nanostructured Lipid Carriers as a Promising DDS for Breast Cancer Treatment
Published in Molecules (Basel, Switzerland) (13-12-2022)“…Breast cancer is the neoplasia of highest incidence in women worldwide. Docetaxel (DTX), a taxoid used to treat breast cancer, is a BCS-class-IV compound (low…”
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Anaesthetic benefits of a ternary drug delivery system (Ropivacaine‐in‐Cyclodextrin‐in‐Liposomes): in‐vitro and in‐vivo evaluation
Published in Journal of pharmacy and pharmacology (01-03-2020)“…Objectives To evaluate whether a ternary system composed of hydroxypropyl‐β‐cyclodextrin (HP‐βCD) further encapsulated into egg phosphatidylcholine liposomes…”
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Antineoplastics Encapsulated in Nanostructured Lipid Carriers
Published in Molecules (Basel, Switzerland) (17-11-2021)“…Ideally, antineoplastic treatment aims to selectively eradicate cancer cells without causing systemic toxicity. A great number of antineoplastic agents (AAs)…”
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