Search Results - "Paul Romeo"

Ultra-high-dose-rate FLASH and Conventional-Dose-Rate Irradiation Differentially Affect Human Acute Lymphoblastic Leukemia and Normal Hematopoiesis by Chabi, Sara, To, Thi Hong Van, Leavitt, Ron, Poglio, Sandrine, Jorge, Patrik Gonçalves, Jaccard, Maud, Petersson, Kristoffer, Petit, Benoit, Roméo, Paul-Henri, Pflumio, Françoise, Vozenin, Marie-Catherine, Uzan, Benjamin

“…Ultra-high-dose-rate FLASH radiation therapy has been shown to minimize side effects of irradiation in various organs while keeping antitumor efficacy. This…”
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NRF2 Activation Impairs Quiescence and Bone Marrow Reconstitution Capacity of Hematopoietic Stem Cells by Murakami, Shohei, Suzuki, Takuma, Harigae, Hideo, Romeo, Paul-Henri, Yamamoto, Masayuki, Motohashi, Hozumi

“…Tissue stem cells are maintained in quiescence under physiological conditions but proliferate and differentiate to replenish mature cells under stressed…”
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In vivo reduction of RAD51-mediated homologous recombination triggers aging but impairs oncogenesis by Matos-Rodrigues, Gabriel, Barroca, Vilma, Muhammad, Ali-Akbar, Dardillac, Elodie, Allouch, Awatef, Koundrioukoff, Stephane, Lewandowski, Daniel, Despras, Emmanuelle, Guirouilh-Barbat, Josée, Frappart, Lucien, Kannouche, Patricia, Dupaigne, Pauline, Le Cam, Eric, Perfettini, Jean-Luc, Romeo, Paul-Henri, Debatisse, Michelle, Jasin, Maria, Livera, Gabriel, Martini, Emmanuelle, Lopez, Bernard S

“…Homologous recombination (HR) is a prominent DNA repair pathway maintaining genome integrity. Mutations in many HR genes lead to cancer predisposition…”
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Keap1‐Nrf2 system regulates cell fate determination of hematopoietic stem cells by Murakami, Shohei, Shimizu, Ritsuko, Romeo, Paul‐Henri, Yamamoto, Masayuki, Motohashi, Hozumi

“…Nrf2 is a major transcriptional activator of cytoprotective genes against oxidative/electrophilic stress, and Keap1 negatively regulates Nrf2. Emerging works…”
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A genetic variant controls interferon-β gene expression in human myeloid cells by preventing C/EBP-β binding on a conserved enhancer by Assouvie, Anaïs, Rotival, Maxime, Hamroune, Juliette, Busso, Didier, Romeo, Paul-Henri, Quintana-Murci, Lluis, Rousselet, Germain

“…Interferon β (IFN-β) is a cytokine that induces a global antiviral proteome, and regulates the adaptive immune response to infections and tumors. Its effects…”
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Trends in the treatment of proximal humerus fractures from 2010 to 2020 by Papalia, Aidan G., Romeo, Paul V., Kingery, Matthew T., Alben, Matthew G., Lin, Charles C., Simcox, Trevor G., Zuckerman, Joseph D., Virk, Mandeep S.

“…The incidence of proximal humerus fractures (PHF) is continuing to rise due to shifts towards a more aged population as well as advancements in surgical…”
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Tumor resistance to radiotherapy is triggered by an ATM/TAK1-dependent-increased expression of the cellular prion protein by Bernardino-Sgherri, Jacqueline, Siberchicot, Capucine, Auvré, Frédéric, Busso, Didier, Brocas, Clémentine, El Masri, Ghazi, Lioutsko, Anna, Ferri, Federica, Radicella, J. Pablo, Romeo, Paul-Henri, Bravard, Anne

“…In solid cancers, high expression of the cellular prion protein (PrPC) is associated with stemness, invasiveness, and resistance to chemotherapy, but the role…”
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MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate by Coutier, Julien, Auvré, Frédéric, Lemaître, Gilles, Lataillade, Jean-Jacques, Deleuze, Jean-François, Roméo, Paul-Henri, Martin, Michèle T., Fortunel, Nicolas O.

“…Deciphering the pathways that regulate human epidermal precursor cell fate is necessary for future developments in skin repair and graft bioengineering. Among…”
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Hematopoietic stem and progenitor cell responses to low radiation doses - implications for leukemia risk by Gault, Nathalie, Verbiest, Tom, Badie, Christophe, Romeo, Paul-Henri, Bouffler, Simon

“…Studies of the responses of hematopoietic stem and progenitor cells (HSPCs) to low doses of ionizing radiation formed an important aspect of the RISK-IR…”
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Low-Dose Irradiation Promotes Persistent Oxidative Stress and Decreases Self-Renewal in Hematopoietic Stem Cells by Rodrigues-Moreira, Sarah, Moreno, Stéphanie G., Ghinatti, Giulia, Lewandowski, Daniel, Hoffschir, Françoise, Ferri, Federica, Gallouet, Anne-Sophie, Gay, Denise, Motohashi, Hozumi, Yamamoto, Masayuki, Joiner, Michael C., Gault, Nathalie, Romeo, Paul-Henri

“…Despite numerous observations linking protracted exposure to low-dose (LD) radiation and leukemia occurrence, the effects of LD irradiation on hematopoietic…”
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A multimodal treatment of carbon ions irradiation, miRNA-34 and mTOR inhibitor specifically control high-grade chondrosarcoma cancer stem cells by Vares, Guillaume, Ahire, Vidhula, Sunada, Shigeaki, Ho Kim, Eun, Sai, Sei, Chevalier, François, Romeo, Paul-Henri, Yamamoto, Tadashi, Nakajima, Tetsuo, Saintigny, Yannick

“…•Chondrosarcoma stem cells (ChSCs) are radioresistant and are suppressed by miR-34.•mTOR inhibition by Rapamycin targets ChSCs via FOXO3 and…”
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Minimal clinically important difference (MCID) and substantial clinical benefit (SCB) of upper extremity PROMIS scores following arthroscopic rotator cuff repairs by Alben, Matthew G., Gordon, Dan, Gambhir, Neil, Kim, Matthew T., Romeo, Paul V., Rokito, Andrew S., Zuckerman, Joseph D., Virk, Mandeep S.

“…Purpose To calculate and determine what factors are associated with achieving the Minimal Clinically Important Difference (MCID) and the Substantial Clinical…”
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Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome by Darghouth, Dhouha, Koehl, Bérengère, Madalinski, Geoffrey, Heilier, Jean-François, Bovee, Petra, Xu, Ying, Olivier, Marie-Françoise, Bartolucci, Pablo, Benkerrou, Malika, Pissard, Serge, Colin, Yves, Galacteros, Frederic, Bosman, Giel, Junot, Christophe, Roméo, Paul-Henri

“…Emerging metabolomic tools can now be used to establish metabolic signatures of specialized circulating hematopoietic cells in physiologic or pathologic…”
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Fetal Muse-based therapy prevents lethal radio-induced gastrointestinal syndrome by intestinal regeneration by Dushime, Honorine, Moreno, Stéphanie G, Linard, Christine, Adrait, Annie, Couté, Yohann, Peltzer, Juliette, Messiaen, Sébastien, Torres, Claire, Bensemmane, Lydia, Lewandowski, Daniel, Romeo, Paul-Henri, Petit, Vanessa, Gault, Nathalie

“…Human multilineage-differentiating stress enduring (Muse) cells are nontumorigenic endogenous pluripotent-like stem cells that can be easily obtained from…”
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Human CCR6+ Th17 Lymphocytes Are Highly Sensitive to Radiation-Induced Senescence and Are a Potential Target for Prevention of Radiation-Induced Toxicity by Nguyen, Hoang Quy, Belkacemi, Yazid, Mann, Carl, Hoffschir, Françoise, Kerbrat, Stéphane, Surenaud, Mathieu, Zadigue, Patricia, de La Taille, Alexandre, Romeo, Paul-Henri, Le Gouvello, Sabine

“…This study addresses the sensitivity of different peripheral CD4+ T-lymphocyte subsets to irradiation (IR) and identifies potential targets for the prevention…”
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Inpatient charges, complication, and revision rates for shoulder arthroplasty in Parkinson disease: a regional database study by Papalia, Aidan G., Kingery, Matthew T., Romeo, Paul V., Simcox, Trevor, Lin, Charles C., Anil, Utkarsh, Zuckerman, Joseph D., Virk, Mandeep S.

“…Parkinson disease (PD) is an established risk factor for higher rates of complications and revision surgery following shoulder arthroplasty, yet the economic…”
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Analysis of patient factors associated with selection of corticosteroid injection in the freezing phase of idiopathic adhesive capsulitis by Adekanye, David, Papalia, Aidan G., Romeo, Paul V., Kingery, Matthew T., Ben-Ari, Erel, Bustamante, Sebastian, Zuckerman, Joseph D., Virk, Mandeep S.

“…Primary idiopathic adhesive capsulitis (AC) is characterized by shoulder pain and global limitations in range of motion (ROM). The aim of this study was to…”
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NOTCH is a key regulator of human T-cell acute leukemia initiating cell activity by Armstrong, Florence, de la Grange, Philippe Brunet, Gerby, Bastien, Rouyez, Marie-Christine, Calvo, Julien, Fontenay, Michaéla, Boissel, Nicolas, Dombret, Hervé, Baruchel, André, Landman-Parker, Judith, Roméo, Paul-Henri, Ballerini, Paola, Pflumio, Françoise

“…Understanding the pathways that regulate the human T-cell acute lymphoblastic leukemia (T-ALL) initiating cells (T-LiC) activity has been hampered by the lack…”
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Does the addition of Patient-Reported Outcome Measure Information System (PROMIS) pain instruments improve the sensitivity of PROMIS upper extremity scores after arthroscopic rotator cuff repair? by Alben, Matthew G., Romeo, Paul V., Papalia, Aidan G., Cecora, Andrew J., Kwon, Young W., Rokito, Andrew S., Zuckerman, Joseph D., Virk, Mandeep S.

“…Although Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (P-UE) has been validated in upper extremity orthopedics, its…”
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Phagocytosis of Wnt inhibitor SFRP4 by late wound macrophages drives chronic Wnt activity for fibrotic skin healing by Gay, Denise, Ghinatti, Giulia, Guerrero-Juarez, Christian F, Ferrer, Rubén A, Ferri, Federica, Lim, Chae Ho, Murakami, Shohei, Gault, Nathalie, Barroca, Vilma, Rombeau, Isabelle, Mauffrey, Philippe, Irbah, Lamya, Treffeisen, Elsa, Franz, Sandra, Boissonnas, Alexandre, Combadière, Christophe, Ito, Mayumi, Plikus, Maksim V, Romeo, Paul-Henri

“…Human and murine skin wounding commonly results in fibrotic scarring, but the murine wounding model wound-induced hair neogenesis (WIHN) can frequently result…”
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