Search Results - "Paul K Drain"

Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection by Drain, Paul K, Bajema, Kristina L, Dowdy, David, Dheda, Keertan, Naidoo, Kogieleum, Schumacher, Samuel G, Ma, Shuyi, Meermeier, Erin, Lewinsohn, David M, Sherman, David R

“…Tuberculosis (TB) is the leading infectious cause of mortality worldwide, due in part to a limited understanding of its clinical pathogenic spectrum of…”
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Diagnostic point-of-care tests in resource-limited settings by Drain, Paul K, Dr, Hyle, Emily P, MD, Noubary, Farzad, PhD, Freedberg, Kenneth A, MD, Wilson, Douglas, MBChB, Bishai, William R, MD, Rodriguez, William, MD, Bassett, Ingrid V, MD

“…Summary The aim of diagnostic point-of-care testing is to minimise the time to obtain a test result, thereby allowing clinicians and patients to make a quick…”
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Point-of-Care Diagnostics (POCD) in Resource-Limited Settings by Drain, Paul K

“…Diagnostic testing is critical to provide adequate healthcare, and the emergence of various rapid point-of-care diagnostics (POCD) allows for greater access…”
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Rapid Diagnostic Testing for SARS-CoV-2 by Drain, Paul K

“…RDTs for SARS-CoV-2 — either molecular nucleic acid amplification tests or antigen-based immunoassays to detect proteins — are approved for persons with…”
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SARS-CoV-2 pandemic expanding in sub-Saharan Africa: Considerations for COVID-19 in people living with HIV by Drain, Paul K., Garrett, Nigel

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Poor supply chain management and stock-outs of point-of-care diagnostic tests in Upper East Region's primary healthcare clinics, Ghana by Kuupiel, Desmond, Tlou, Boikhutso, Bawontuo, Vitalis, Drain, Paul K, Mashamba-Thompson, Tivani P

“…Several supply chain components are important to sustain point-of-care (POC) testing services in rural settings. To evaluate the availability of POC diagnostic…”
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Present outlooks on the prevalence of minimal and subclinical tuberculosis and current diagnostic tests: A systematic review and meta-analysis by Mahmoudi, Shima, Hamidi, Mehrsa, Drain, Paul K.

“…Tuberculosis (TB) is a major global health issue, particularly in its minimal and subclinical forms, which often go undetected and contribute to transmission…”
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Point-Of-Care Urine LAM Tests for Tuberculosis Diagnosis: A Status Update by Bulterys, Michelle A, Wagner, Bradley, Redard-Jacot, Maël, Suresh, Anita, Pollock, Nira R, Moreau, Emmanuel, Denkinger, Claudia M, Drain, Paul K, Broger, Tobias

“…Most diagnostic tests for tuberculosis (TB) rely on sputum samples, which are difficult to obtain and have low sensitivity in immunocompromised patients,…”
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Comparative cost analysis of point-of-care versus laboratory-based testing to initiate and monitor HIV treatment in South Africa by Simeon, Kate, Sharma, Monisha, Dorward, Jienchi, Naidoo, Jessica, Dlamini, Ntuthu, Moodley, Pravikrishnen, Samsunder, Natasha, Barnabas, Ruanne V, Garrett, Nigel, Drain, Paul K

“…The number of people living with HIV (PLHIV) in need of treatment monitoring in low-and-middle-income countries has been rapidly expanding, placing an…”
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Diagnostic Accuracy of the Alere Afinion AS100 Point-of-Care Assay to Screen for Noncommunicable Diseases Among People Living With HIV by Bodley, Nicola, Dorward, Jienchi, Naidoo, Jessica, Letsoalo, Marothi, Ramsaroop, Kaminee, Sayed, Fathima, Sookrajh, Yukteshwar, Drain, Paul K., Garrett, Nigel

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Delivery of Community-based Antiretroviral Therapy to Maintain Viral Suppression and Retention in Care in South Africa by Wang, Melody, Violette, Lauren R, Dorward, Jienchi, Ngobese, Hope, Sookrajh, Yukteshwar, Bulo, Elliot, Quame-Amaglo, Justice, Thomas, Katherine K, Garrett, Nigel, Drain, Paul K

“…To determine whether the Centralized Chronic Medication Dispensing and Distribution (CCMDD) program in South Africa's differentiated ART delivery model affects…”
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Global migration of clinical research during the era of trial registration by Drain, Paul K, Parker, Robert A, Robine, Marion, Holmes, King K, Bassett, Ingrid V

“…Since the site of human subjects research has public health, regulatory, ethical, economic, and social implications, we sought to determine the global…”
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Reflections From School Communities in Underserved Populations on Childhood COVID-19 Vaccination by Pulgaron, Elizabeth R, D'Agostino, Emily M, Johnson, Sara B, Ko, Linda K, Drain, Paul K, Duran, Miriana C, Keener Mast, Dana, Kay, Shelley, Layer, Marcus A, Kenworthy, Tara, Dozier, Ann

“…Outbreaks in vaccine-preventable diseases among children have increased, primarily among under- or unvaccinated subgroups. The influence and interaction of a…”
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Supply chain management and accessibility to point-of-care testing in resource-limited settings: a systematic scoping review by Kuupiel, Desmond, Bawontuo, Vitalis, Drain, Paul K, Gwala, Nonjabulo, Mashamba-Thompson, Tivani P

“…World Health Organization (WHO) has created an essential list of in-vitro diagnostics. Supply chain management (SCM) is said to be the vehicle that ensures…”
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Point-of-Care Viral Load Testing to Manage HIV Viremia During the Rollout of Dolutegravir-Based ART in South Africa: A Randomized Feasibility Study (POwER) by Dorward, Jienchi, Sookrajh, Yukteshwar, Lessells, Richard, Bulo, Elliot, Naidoo, Jessica, Naidoo, Keshani, Bodley, Nicola, Khanyile, Mlungisi, Van Vuuren, Claudia Jansen, Moodley, Pravikrishnen, Samsunder, Natasha, Lewis, Lara, Drain, Paul K., Hayward, Gail, Butler, Christopher C., Garrett, Nigel

“…Data are required regarding the feasibility of conducting a randomized trial of point-of-care viral load (VL) testing to guide management of HIV viremia and to…”
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Hepatitis B prevalence and risk factors among adults living with HIV in South Africa: a clinic-based cohort study by Shivakumar, Megana, Moe, Caitlin A, Bardon, Ashley, Krows, Meighan, Govere, Sabina, Moosa, Mahomed Yunus S, Celum, Connie, Drain, Paul K

“…People living with HIV (PLHIV) may have concurrent Hepatitis B Virus (HBV) infection, and certain antiretroviral therapies are recommended for HBV-HIV…”
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Food Insecurity at HIV Diagnosis Associated with Subsequent Viremia Amongst Adults Living with HIV in an Urban Township of South Africa by Nkinsi, Naomi T., Galagan, Sean R., Benzekri, Noelle A., Govere, Sabina, Drain, Paul K.

“…We assessed the temporal impact of food insecurity on 12-month antiretroviral (ART) adherence, retention in care, hospitalization, and HIV viremia (> 1000…”
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Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research by Dorward, Jienchi, Lessells, Richard, Drain, Paul K, Naidoo, Kogieleum, de Oliveira, Tulio, Pillay, Yogan, Abdool Karim, Salim S, Garrett, Nigel

“…A new first-line antiretroviral therapy (ART) regimen containing dolutegravir is being rolled out in low-income and middle-income countries (LMICs). In studies…”
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Effect of perceived HIV risk on initiation of antiretroviral therapy during the universal test and treat era in South Africa by Govere, Sabina M, Galagan, Sean, Tlou, Boikhutso, Mashamba-Thompson, Tivani, Bassett, Ingrid V, Drain, Paul K

“…South Africa has not achieved the 90-90-90 goals, in part due to low rates of antiretroviral therapy (ART) initiation among those aware of their HIV status…”
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Understanding how community antiretroviral delivery influences engagement in HIV care: a qualitative assessment of the Centralised Chronic Medication Dispensing and Distribution programme in South Africa by Dorward, Jienchi, Msimango, Lindani, Gibbs, Andrew, Shozi, Hlengiwe, Tonkin-Crine, Sarah, Hayward, Gail, Butler, Christopher C, Ngobese, Hope, Drain, Paul K, Garrett, Nigel

“…IntroductionProviding antiretroviral therapy (ART) for millions of people living with HIV requires efficient, client-centred models of differentiated ART…”
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