Search Results - "Paul Chiarelli, M."

Enrichment of polycyclic aromatic hydrocarbon metabolizing microorganisms on the oral mucosa of tobacco users by Tao, Lin, Chiarelli, M Paul, Pavlova, Sylvia, Kolokythas, Antonia, Schwartz, Joel, DeFrancesco, James, Salameh, Benjamin, Green, Stefan J, Adami, Guy

“…Certain soil microbes resist and metabolize polycyclic aromatic hydrocarbons (PAHs). The same is true for a subset of skin microbes. In the human mouth, oral…”
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Conformational and thermodynamic properties modulate the nucleotide excision repair of 2-aminofluorene and 2-acetylaminofluorene dG adducts in the NarI sequence by Jain, Vipin, Hilton, Benjamin, Patnaik, Satyakam, Zou, Yue, Chiarelli, M Paul, Cho, Bongsup P

“…Nucleotide excision repair (NER) is a major repair pathway that recognizes and corrects various lesions in cellular DNA. We hypothesize that damage recognition…”
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Biotransformation of flumequine by the fungus Cunninghamella elegans by Williams, Anna J., Deck, Joanna, Freeman, James P., Paul Chiarelli, M., Adjei, Michael D., Heinze, Thomas M., Sutherland, John B.

“…The metabolism of the antibacterial fluoroquinolone drug flumequine by Cunninghamella elegans was investigated using cultures grown in Sabouraud dextrose broth…”
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A Gcn5-Related N‑Acetyltransferase (GNAT) Capable of Acetylating Polymyxin B and Colistin Antibiotics in Vitro by Czub, Mateusz P, Zhang, Brian, Chiarelli, M. Paul, Majorek, Karolina A, Joe, Layton, Porebski, Przemyslaw J, Revilla, Alina, Wu, Weiming, Becker, Daniel P, Minor, Wladek, Kuhn, Misty L

“…Deeper exploration of uncharacterized Gcn5-related N-acetyltransferases has the potential to expand our knowledge of the types of molecules that can be…”
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Functionalization of organic semiconductor crystals via the Diels-Alder reaction by Qualizza, Brittni A, Prasad, Srividya, Chiarelli, M Paul, Ciszek, Jacob W

“…A surface adlayer is generated on organic single crystals (tetracene and rubrene) using the site specific Diels-Alder reaction and a series of vapor phase…”
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Differentiation of isomeric C8-substituted alkylaniline adducts of guanine by electrospray ionization and tandem quadrupole ion trap mass spectrometry by Li, Linge, Chiarelli, M.Paul, Branco, Paula S, Antunes, Alexandra M, Marques, M.Matilde, Gonçalves, Luísa L, Beland, Frederick A

“…Product ion spectra from thirteen C8-substituted alkylaniline adducts of guanine and deoxyguanosine were generated using electrospray ionization and quadrupole…”
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Spectroscopic and Theoretical Insights into Sequence Effects of Aminofluorene-Induced Conformational Heterogeneity and Nucleotide Excision Repair by Meneni, Srinivasa Rao, Shell, Steven M, Gao, Lan, Jurecka, Petr, Lee, Wang, Sponer, Jiri, Zou, Yue, Chiarelli, M. Paul, Cho, Bongsup P

“…A systematic spectroscopic and computational study was conducted in order to probe the influence of base sequences on stacked (S) versus B-type (B)…”
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α,β-Methylene-2′-deoxynucleoside 5′-Triphosphates as Noncleavable Substrates for DNA Polymerases: Isolation, Characterization, and Stability Studies of Novel 2′-Deoxycyclonucleosides, 3,5′-Cyclo-dG, and 2,5′-Cyclo-dT by Liang, Fengting, Jain, Nidhi, Hutchens, Troy, Shock, David D, Beard, William A, Wilson, Samuel H, Chiarelli, M. Paul, Cho, Bongsup P

“…We report synthesis and characterization of a complete set of α,β-methylene-2′-dNTPs (α,β-m-dNTP; N = A, C, T, G, 12−15) in which the α,β-oxygen linkage of…”
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Nitramine Anion Fragmentation: A Mass Spectrometric and Ab Initio Study by Florián, Jan, Gao, Lan, Zhukhovskyy, Vladimir, MacMillan, Denise K., Chiarelli, M. Paul

“…The fragment ion formation characteristics of the radical anions generated from hexahydro-1,3,5-trinitrotriazine (RDX) and its three nitroso metabolites were…”
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Product ion studies of diastereomeric benzo[ghi]fluoranthene tetraols by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and post-source decay by Huffer, Duane M, Chang, Hui-Fang, Cho, Bongsup P, Zhang, Li Kang, Chiarelli, M.Paul

“…The product ion formation characteristics of the four diastereomeric tetrahydroxy benzo[ghi]fluoranthene compounds formed by hydrolysis of the syn and anti…”
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Sequence Verification of Oligonucleotides Containing Multiple Arylamine Modifications by Enzymatic Digestion and Liquid Chromatography Mass Spectrometry (LC/MS) by Gao, Lan, Zhang, Li, Cho, Bongsup P., Chiarelli, M. Paul

“…An analytical method for the structure differentiation of arylamine modified oligonucleotides (ODNs) using on-line LC/MS analysis of raw exonuclease digests is…”
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Fluorescence Probing of Aminofluorene-Induced Conformational Heterogeneity in DNA Duplexes by Jain, Nidhi, Reshetnyak, Yana K, Gao, Lan, Chiarelli, M. Paul, Cho, Bongsup P

“…Fluorescence spectroscopy was used to study carcinogen-induced conformational heterogeneity in DNA duplexes. The fluorophore 2-aminopurine (AP) was…”
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Sequence effects of aminofluorene-modified DNA duplexes: thermodynamic and circular dichroism properties by Meneni, Srinivasa Rao, D'Mello, Rhijuta, Norigian, Gregory, Baker, Gregory, Gao, Lan, Chiarelli, M. Paul, Cho, Bongsup P.

“…Circular dichroism (CD) and UV-melting experiments were conducted with 16 oligodeoxynucleotides modified by the carcinogen 2-aminofluorene, whose sequence…”
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Improved cell typing by charge-state deconvolution of matrix-assisted laser desorption/ionization mass spectra by Wilkes, Jon G., Buzatu, Dan A., Dare, Diane J., Dragan, Yvonne P., Chiarelli, M. Paul, Holland, Ricky D., Beaudoin, Michael, Heinze, Thomas M., Nayak, Rajesh, Shvartsburg, Alexandre A.

“…Robust, specific, and rapid identification of toxic strains of bacteria and viruses, to guide the mitigation of their adverse health effects and optimum…”
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Product ion studies of diastereomeric benzo[ghi]fluoranthene-2′-deoxynucleoside adducts by electrospray ionization and quadrupole ion trap mass spectrometry by Li, Linge, Chang, Hui-Fang, Olsen, Kenneth W., Cho, Bongsup P., Chiarelli, M. Paul

“…The product ion formation characteristics of the protonated molecule ions generated from 10 different deoxynucleoside adducts of benzo[ghi]fluoranthene…”
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Sequence effects of aminofluorene-modified DNA duplexes: thermodynamic and circular dichroism properties by Meneni, Srinivasa Rao, D'Mello, Rhijuta, Norigian, Gregory, Baker, Gregory, Gao, Lan, Chiarelli, M. Paul, Cho, Bongsup P.

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Structural Differentiation of Diastereomeric Benzo[ghi]fluoranthene Adducts of Deoxyadenosine by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Postsource Decay by Chiarelli, M. Paul, Chang, Hui-Fang, Olsen, Kenneth W, Barbacci, Damon, Cho, Bongsup P

“…The product ion formation characteristics of four diastereomeric deoxyadenosine adducts formed by the reaction of the syn and anti diastereomers of…”
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Characterization of DNA Adducts and Tetraols Derived from anti-Benzo[ghi]fluoranthane-3,4-dihydrodiol-5,5a-epoxide by Chang, Hui-Fang, Huffer, Duane M, Chiarelli, M. Paul, Cho, Bongsup P

“…A total of seven DNA adducts and two racemic tetraols derived from anti-benzo[ghi]fluoranthene-3,4-dihydrodiol-5,5a-epoxide (anti-B[ghi]FDE, 2) were…”
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Characterization of DNA Adducts Derived from syn-Benzo[ghi]fluoranthene- 3,4-dihydrodiol-5,5a-epoxide and Comparative DNA Binding Studies with Structurally-Related anti-Diolepoxides of Benzo[ghi]fluoranthene and Benzo[c]phenanthrene by Chang, Hui-Fang, Huffer, Duane M, Chiarelli, M. Paul, Blankenship, Lonnie R, Culp, Sandra J, Cho, Bongsup P

“…This paper reports structural characterization of the adducts and tetraols formed from syn-benzo[ghi]fluoranthene-3,4-dihydrodiol-5,5a-epoxide (syn-B[ghi]FDE,…”
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New Syntheses of DNA Adducts from Methylated Anilines Present in Tobacco Smoke by Branco, Paula S, Antunes, Alexandra M. M, Marques, M. Matilde, Chiarelli, M. Paul, Lobo, Ana M, Prabhakar, Sundaresan

“…A new synthetic pathway for the formation of deoxyguanosine−monoarylamine adducts is described, involving the generation and use of arylnitrenes as…”
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