Search Results - "Paul, T J"
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1
Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus
Published in PLoS genetics (01-01-2013)“…When growing populations of bacteria are confronted with bactericidal antibiotics, the vast majority of cells are killed, but subpopulations of genetically…”
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2
The COVID-19 pandemic: a moment for exposure science
Published in Journal of exposure science & environmental epidemiology (01-07-2020)Get full text
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3
Generic prediction of exocytosis rate constants by size-based surface energies of nanoparticles and cells
Published in Scientific reports (24-10-2022)“…Nanotechnology brings benefits in fields such as biomedicine but nanoparticles (NPs) may also have adverse health effects. The effects of surface-modified NPs…”
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4
Usage patterns of personal care products: Important factors for exposure assessment
Published in Food and chemical toxicology (01-05-2013)“…► In addition to usage patterns, circumstances of use (e.g. the presence of ventilation) are incorporated in this study. ► The prevalence, frequency and amount…”
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5
Biomonitoring of blood cholinesterases and acylpeptide hydrolase activities in rural inhabitants exposed to pesticides in the Coquimbo Region of Chile
Published in PloS one (02-05-2018)“…In Chile, agriculture is a relevant economic activity and is concomitant with the use of pesticides to improve the yields. Acute intoxications of agricultural…”
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Reduced neurobehavioral functioning in agricultural workers and rural inhabitants exposed to pesticides in northern Chile and its association with blood biomarkers inhibition
Published in Environmental health (22-07-2020)“…Abstract Background Previous biomonitoring studies have shown that people in the rural population of Coquimbo, the major agricultural area in northern Chile…”
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7
Exposure science perspective on disaster preparedness and resilience
Published in Journal of exposure science & environmental epidemiology (01-09-2021)Get full text
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8
Towards further harmonization of a glossary for exposure science—an ISES Europe statement
Published in Journal of exposure science & environmental epidemiology (01-07-2022)“…The use of aligned exposure science terminology is crucial for ease of comparison and appropriate interpretation of exposure information, regulatory reports,…”
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9
Do initial concentration and activated sludge seasonality affect pharmaceutical biotransformation rate constants?
Published in Applied microbiology and biotechnology (01-08-2021)“…Pharmaceuticals find their way to the aquatic environment via wastewater treatment plants (WWTPs). Biotransformation plays an important role in mitigating…”
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10
Establishing a health-based recommended occupational exposure limit for isoflurane using experimental animal data: a systematic review protocol
Published in Systematic reviews (14-09-2023)“…Abstract Background Isoflurane is used as an inhalation anesthetic in medical, paramedical, and veterinary practice. Epidemiological studies suggest an…”
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11
Pesticide exposure: the hormonal function of the female reproductive system disrupted?
Published in Reproductive biology and endocrinology (31-05-2006)“…Some pesticides may interfere with the female hormonal function, which may lead to negative effects on the reproductive system through disruption of the…”
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12
The updated national research agenda 2021–2026 for prehospital emergency medical services in the Netherlands: a Delphi study
Published in Scandinavian journal of trauma, resuscitation and emergency medicine (20-11-2021)“…Abstract Background In 2015, a national research agenda was established for Dutch prehospital EMS to underpin the evidence base of care delivery and inform…”
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13
The pharmaco -, population and evolutionary dynamics of multi-drug therapy: experiments with S. aureus and E. coli and computer simulations
Published in PLoS pathogens (01-04-2013)“…There are both pharmacodynamic and evolutionary reasons to use multiple rather than single antibiotics to treat bacterial infections; in combination…”
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14
Differences in 90-day mortality of delirium subtypes in the intensive care unit: A retrospective cohort study
Published in Journal of critical care (01-10-2019)“…Many intensive care unit (ICU) patients suffer from delirium which is associated with deleterious short-term and long-term effects, including mortality. We…”
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15
European educational practices for the critical care nursing profession – Let’s align for the future
Published in Intensive & critical care nursing (01-08-2024)Get full text
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16
MtrR Modulates rpoH Expression and Levels of Antimicrobial Resistance in Neisseria gonorrhoeae
Published in Journal of Bacteriology (01-01-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Diagnosis, monitoring and prevention of exposure-related non-communicable diseases in the living and working environment: DiMoPEx-project is designed to determine the impacts of environmental exposure on human health
Published in Journal of occupational medicine and toxicology (London, England) (05-02-2018)“…The WHO has ranked environmental hazardous exposures in the living and working environment among the top risk factors for chronic disease mortality. Worldwide,…”
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Response to the Letter: Can delirium subtypes predict differences in 90-day mortality in the intensive care unit? - The authors reply
Published in Journal of critical care (01-04-2020)“…[...]the responders believe it is inadvisable to divide patients into groups by a simple measurement of delirium, and state that the effect of age on the…”
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MpeR Regulates the mtr Efflux Locus in Neisseria gonorrhoeae and Modulates Antimicrobial Resistance by an Iron-Responsive Mechanism
Published in Antimicrobial Agents and Chemotherapy (01-03-2012)“…Previous studies have shown that the MpeR transcriptional regulator produced by Neisseria gonorrhoeae represses the expression of mtrF, which encodes a…”
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20
Concentration and distribution of pesticide residues in soil: Non-dietary human health risk assessment
Published in Chemosphere (Oxford) (01-08-2020)“…Soil contamination by pesticide residues is a primary concern because of the high soil persistence of pesticides and their toxicity to humans. We investigated…”
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