Search Results - "Paul, Susan"
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Application and utility of mass cytometry in vaccine development
Published in The FASEB journal (01-01-2018)“…Mass cytometry enables highly multiplexed profiling of cellular immune responses in limited‐volume samples, advancing prospects of a new era of systems…”
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Cytometry profiling of ex vivo recall responses to Coxiella burnetii in previously naturally exposed individuals reveals long-term changes in both adaptive and innate immune cellular compartments
Published in Frontiers in immunology (11-10-2023)“…IntroductionQ fever, caused by the intracellular bacterium Coxiella burnetii, is considered an occupational and biodefense hazard and can result in…”
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3
Promiscuous Coxiella burnetii CD4 Epitope Clusters Associated With Human Recall Responses Are Candidates for a Novel T-Cell Targeted Multi-Epitope Q Fever Vaccine
Published in Frontiers in immunology (15-02-2019)“…, the causative agent of Q fever, is a Gram-negative intracellular bacterium transmitted via aerosol. Regulatory approval of the Australian whole-cell vaccine…”
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4
Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates
Published in Science translational medicine (05-04-2023)“…Hematopoietic stem cell transplantation (HSCT) has many potential applications beyond current standard indications, including treatment of autoimmune disease,…”
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Coxiella burnetii Epitope-Specific T-Cell Responses in Patients with Chronic Q Fever
Published in Infection and immunity (01-10-2019)“…Infection with , the causative agent of Q fever, can result in life-threatening persistent infection. Reactogenicity hinders worldwide implementation of the…”
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Deep immune profiling of whole blood to identify early immune signatures that correlate to patient outcome after major trauma
Published in The journal of trauma and acute care surgery (01-06-2021)“…Major injury results in an early cascade of immunologic responses that increase susceptibility to infection and multiorgan dysfunction. Detailed immune…”
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“Docking Sites”: Nanometer-Scale Organization of a Reactive, Protein-resistant, Graft Copolymer-Based Interface for Macromolecule Immobilization
Published in Biomacromolecules (12-12-2011)“…The signal-to-noise ratio of a sensor system is determined by the affinity of its active component for the analyte on one hand and its inertness with respect…”
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Biotin-Derivatized Poly(l-lysine)-g-poly(ethylene glycol): A Novel Polymeric Interface for Bioaffinity Sensing
Published in Langmuir (08-01-2002)“…A novel biosensor interface exploiting the spontaneous surface assembly of a polycationic, PEG-grafted, biotinylated copolymer was developed and tested on…”
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Atropisomeric Racemization Kinetics of MRTX1719 Using Chiral Solvating Agent-Assisted 19F NMR Spectroscopy
Published in ACS omega (13-09-2022)“…With renewed interest in atropisomerism of drug molecules, efficient methods to experimentally determine torsion rotational energy barriers are needed. Here,…”
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Functional limitation among older adults in a rural area in South Kerala and its associated factors
Published in Journal of the Indian academy of geriatrics (01-01-2023)“…Background: A person is said to have a functional limitation when he/she does not have the physical or cognitive ability to independently perform the routine…”
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Boundary Lubrication of Oxide Surfaces by Poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) in Aqueous Media
Published in Tribology letters (01-10-2003)“…In this work, we have explored the application of poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) as an additive to improve the lubricating properties of…”
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Reduction of Friction at Oxide Interfaces upon Polymer Adsorption from Aqueous Solutions
Published in Langmuir (20-01-2004)“…Reduction of the interfacial friction for the contact of a silicon oxide surface with sodium borosilicate in aqueous solutions has been accomplished through…”
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Natural Exposure- and Vaccination-Induced Profiles of Ex Vivo Whole Blood Cytokine Responses to Coxiella burnetii
Published in Frontiers in immunology (23-06-2022)“…Q fever is a zoonotic disease caused by the highly infectious Gram-negative coccobacillus, Coxiella burnetii ( C. burnetii ). The Q fever vaccine Q-VAX ® is…”
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14
Geriatric health policy in India: The need for scaling-up implementation
Published in Journal of family medicine and primary care (01-07-2016)“…In an anticipation of the rising geriatric population in India, the Central government constituted the National Policy for Older Persons in 1999 to promote the…”
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Evaluation of a Human T Cell-Targeted Multi-Epitope Vaccine for Q Fever in Animal Models of Coxiella burnetii Immunity
Published in Frontiers in immunology (16-05-2022)“…T cell-mediated immunity plays a central role in the control and clearance of intracellular infection, which can cause Q fever. Therefore, we aimed to develop…”
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Structure, Mobility, and Interface Characterization of Self-Organized Organic−Inorganic Hybrid Materials by Solid-State NMR
Published in Journal of the American Chemical Society (23-06-1999)“…The local chemical environments, dynamic heterogeneities, and nature of the interface in structured organic−inorganic composites prepared from…”
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The Relationship Between Socioeconomic Status and Dental Caries Among Adults in India: A Scoping Review
Published in Journal of Research & Health (01-05-2024)“…Background: It is well documented that India is an example of the unequal distribution of dental caries among different population groups, as higher prevalence…”
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Depression among geriatric population; the need for community awareness
Published in Clinical epidemiology and global health (01-03-2019)“…To measure the prevalence of depression among the rural elderly population of North Tamilnadu in India and to identify the associated social factors. A…”
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Q-vaxcelerate: A distributed development approach for a new Coxiella burnetii vaccine
Published in Human vaccines & immunotherapeutics (02-12-2017)“…Development of vaccines that are both safe and effective remains a costly and time-consuming challenge. To accelerate the pace of development and improve the…”
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Comparison of strain generated in bone by "platform-switched" and "non-platform-switched" implants with straight and angulated abutments under vertical and angulated load: A finite element analysis study
Published in Indian journal of dental research (01-01-2013)“…Purpose: The aim of this study was to evaluate the microstrain exhibited by bone around immediately loaded, platform-switched, and non-platform-switched…”
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