Search Results - "Paul, Sanchari"
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An adjuvant-containing cDC1-targeted recombinant fusion vaccine conveys strong protection against murine melanoma growth and metastasis
Published in Oncoimmunology (31-12-2022)“…Type 1 conventional dendritic cells (cDC1) efficiently cross-present antigens that prime cytotoxic CD8 + T cells. cDC1 therefore constitute conceivable targets…”
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Active bacterial modification of the host environment through RNA polymerase II inhibition
Published in The Journal of clinical investigation (15-02-2021)“…Unlike pathogens, which attack the host, commensal bacteria create a state of friendly coexistence. Here, we identified a mechanism of bacterial adaptation to…”
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Multiomic Single-Cell Analysis Identifies Von Willebrand Factor and TIM3-Expressing BCR-ABL1+ Chronic Myeloid Leukemia Stem Cells
Published in Blood (02-11-2023)“…Characterization of the leukemic stem cell (LSC) population in chronic myeloid leukemia (CML) may identify therapeutic targets for sustained elimination of…”
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Beta-sheet-specific interactions with heat shock proteins define a mechanism of delayed tumor cell death in response to HAMLET
Published in Journal of molecular biology (28-06-2019)“…As chaperones, heat shock proteins (HSPs) protect host cells against misfolded proteins that constitute a by-product of protein synthesis. Certain HSPs are…”
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Peptide-Oleate Complexes Create Novel Membrane-Bound Compartments
Published in Molecular biology and evolution (01-11-2020)“…A challenging question in evolutionary theory is the origin of cell division and plausible molecular mechanisms involved. Here, we made the surprising…”
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Impact of surgery-induced myeloid-derived suppressor cells and the NOX2/ROS axis on post-operative survival in human pancreatic cancer
Published in Cancer research communications (10-04-2024)“…Preclinical studies imply that surgery triggers inflammation that may entail tumor outgrowth and metastasis. The potential impact of surgery-induced…”
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Impact of Surgery-Induced Myeloid-derived Suppressor Cells and the NOX2/ROS Axis on Postoperative Survival in Human Pancreatic Cancer
Published in Cancer research communications (25-04-2024)“…Preclinical studies imply that surgery triggers inflammation that may entail tumor outgrowth and metastasis. The potential impact of surgery-induced…”
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