Search Results - "Paul, S."
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1
Coronavirus genomic RNA packaging
Published in Virology (New York, N.Y.) (01-11-2019)“…RNA viruses carry out selective packaging of their genomes in a variety of ways, many involving a genomic packaging signal. The first coronavirus packaging…”
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2
Haematopoietic stem cell activity and interactions with the niche
Published in Nature reviews. Molecular cell biology (01-05-2019)“…The haematopoietic stem cell (HSC) microenvironment in the bone marrow, termed the niche, ensures haematopoietic homeostasis by controlling the proliferation,…”
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3
Hematopoietic stem cell niche maintenance during homeostasis and regeneration
Published in Nature medicine (01-08-2014)“…The maintenance and proliferation of hematopoietic stem cells after injury is regulated by signals from the bone marrow stem cell niche. The bone marrow niche…”
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4
Niches for Hematopoietic Stem Cells and Their Progeny
Published in Immunity (Cambridge, Mass.) (17-04-2018)“…Steady-state hematopoietic stem cells’ (HSCs) self-renewal and differentiation toward their mature progeny in the adult bone marrow is tightly regulated by…”
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Differential cytokine contributions of perivascular haematopoietic stem cell niches
Published in Nature cell biology (01-03-2017)“…Arterioles and sinusoids of the bone marrow (BM) are accompanied by stromal cells that express nerve/glial antigen 2 (NG2) and leptin receptor (LepR), and…”
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6
New developments in force fields for biomolecular simulations
Published in Current opinion in structural biology (01-04-2018)“…•Biomolecular force fields (FFs) have progressed rapidly in the past five years.•Fixed-charge FF accuracy has improved, but challenges remain for complex…”
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7
Niche heterogeneity in the bone marrow
Published in Annals of the New York Academy of Sciences (01-04-2016)“…In adult mammals, hematopoietic stem cells (HSCs) are defined by their abilities to self‐renew and to differentiate to form all blood cell lineages. These rare…”
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8
Circadian control of the immune system
Published in Nature reviews. Immunology (01-03-2013)“…Key Points Circadian rhythms are endogenous oscillations in organisms of ∼24 hours in length that exist in virtually all cells. The number of circulating…”
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9
Neural Regulation of Hematopoiesis, Inflammation, and Cancer
Published in Neuron (Cambridge, Mass.) (22-04-2015)“…Although the function of the autonomic nervous system (ANS) in mediating the flight-or-fight response was recognized decades ago, the crucial role of…”
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10
Evolution of central pattern generators and rhythmic behaviours
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-01-2016)“…Comparisons of rhythmic movements and the central pattern generators (CPGs) that control them uncover principles about the evolution of behaviour and neural…”
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11
The first step for neuroimaging data analysis: DICOM to NIfTI conversion
Published in Journal of neuroscience methods (01-05-2016)“…•Introduce conversion tools for different vendors.•Explain conversion basics.•Present methods to detect and correctproblems. Clinical imaging data are…”
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12
New Horizons in the Treatment of Osteosarcoma
Published in The New England journal of medicine (25-11-2021)“…Osteosarcoma, which is most common in people 10 to 30 years of age, is generally treated with resection and adjuvant chemotherapy. Detection of gene…”
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13
Crystal structure of a human GABAA receptor
Published in Nature (London) (21-08-2014)“…Type-A γ-aminobutyric acid receptors (GABA A Rs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABA A…”
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14
Dynamic Axonal Translation in Developing and Mature Visual Circuits
Published in Cell (30-06-2016)“…Local mRNA translation mediates the adaptive responses of axons to extrinsic signals, but direct evidence that it occurs in mammalian CNS axons in vivo is…”
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15
Mitigating the risks of surgery during the COVID-19 pandemic
Published in The Lancet (British edition) (04-07-2020)“…Risk factors for mortality were patient age of 70 years or older, male sex, poor preoperative physical health status, emergency versus elective surgery,…”
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Assessment of Patients' Competence to Consent to Treatment
Published in The New England journal of medicine (01-11-2007)“…A 75-year-old woman has type 2 diabetes mellitus, peripheral vascular disease, and a gangrenous ulcer of her left foot. A below-the-knee amputation is…”
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17
The macular carotenoids: A biochemical overview
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-11-2020)“…Among the more than 750 carotenoids identified in nature, only lutein, zeaxanthin, meso-zeaxanthin, and their oxidative metabolites are selectively accumulated…”
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18
Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine
Published in Stem cells (Dayton, Ohio) (01-05-2009)“…Many of the earliest stem cell studies were conducted on cells isolated from tumors rather than from embryos. Of particular interest was research on embryonic…”
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19
Beyond Hofmeister
Published in Nature chemistry (01-04-2014)“…Research efforts related to the Hofmeister series of salt ions have waxed and waned during its long and storied history. The past few decades have, however,…”
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20
Epidemiology of Lyme Disease
Published in Infectious disease clinics of North America (01-06-2015)“…Lyme disease is the most common vector-borne illness in North America and Europe. The etiologic agent, Borrelia burgdorferi sensu lato, is transmitted to…”
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