Search Results - "Paul, M."

Pulmonary Arterial Hypertension by Hassoun, Paul M

“…Without effective treatment, pulmonary arterial hypertension results in high morbidity and mortality. This review discusses the pathogenesis of the disorder,…”
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From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection by Ridker, Paul M

“…Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) predict vascular risk with an effect estimate as large as that of total…”
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COVID‐19 and the New Technologies of Organizing: Digital Exhaust, Digital Footprints, and Artificial Intelligence in the Wake of Remote Work by Leonardi, Paul M.

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Anticytokine Agents: Targeting Interleukin Signaling Pathways for the Treatment of Atherothrombosis by Ridker, Paul M

“…The recognition that atherosclerosis is a complex chronic inflammatory disorder mediated through both adaptive and innate immunity has led to the hypothesis…”
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Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease by Ridker, Paul M., Rane, Manas

“…IL (interleukin)-6 is a pivotal cytokine of innate immunity, which enacts a broad set of physiological functions traditionally associated with host defense,…”
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Social Media, Knowledge Sharing, and Innovation: Toward a Theory of Communication Visibility by Leonardi, Paul M.

“…This paper offers a theory of communication visibility based on a field study of the implementation of a new enterprise social networking site in a large…”
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Ambient Awareness and Knowledge Acquisition: Using Social Media to Learn “Who Knows What” and “Who Knows Whom” by Leonardi, Paul M.

“…The argument proffered in this paper is that use of enterprise social networking technologies can increase the accuracy of people’s metaknowledge (knowledge of…”
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A Test in Context: High-Sensitivity C-Reactive Protein by Ridker, Paul M

“…The inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) adds prognostic information on cardiovascular risk comparable to blood pressure or…”
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Clinician's Guide to Reducing Inflammation to Reduce Atherothrombotic Risk: JACC Review Topic of the Week by Ridker, Paul M

“…Life-threatening cardiovascular events occur despite control of conventional risk factors. Inflammation, as measured by high-sensitivity C-reactive protein…”
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How Common Is Residual Inflammatory Risk? by Ridker, Paul M

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Novel Stroke Therapeutics: Unraveling Stroke Pathophysiology and Its Impact on Clinical Treatments by George, Paul M., Steinberg, Gary K.

“…Stroke remains a leading cause of death and disability in the world. Over the past few decades our understanding of the pathophysiology of stroke has…”
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From RESCUE to ZEUS: will interleukin-6 inhibition with ziltivekimab prove effective for cardiovascular event reduction? by Ridker, Paul M

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From CANTOS to CIRT to COLCOT to Clinic: Will All Atherosclerosis Patients Soon Be Treated With Combination Lipid-Lowering and Inflammation-Inhibiting Agents? by Ridker, Paul M

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Should Aspirin Be Used for Primary Prevention in the Post-Statin Era? by Ridker, Paul M

“…Between 1853 and 1897, German chemists learned to efficiently combine sodium salicylate with acetyl chloride to produce acetylsalicylic acid. That compound,…”
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Chronic inflammation in multiple sclerosis — seeing what was always there by Matthews, Paul M.

“…Activation of innate immune cells and other compartmentalized inflammatory cells in the brains and spinal cords of people with relapsing–remitting multiple…”
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Continuous Renal Replacement Therapy: Who, When, Why, and How by Tandukar, Srijan, Palevsky, Paul M

“…Continuous renal replacement therapy (CRRT) is commonly used to provide renal support for critically ill patients with acute kidney injury, particularly…”
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Epigenetics and Genetics of Viral Latency by Lieberman, Paul M.

“…Viral latency can be considered a metastable, nonproductive infection state that is capable of subsequent reactivation to repeat the infection cycle. Viral…”
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When Does Technology Use Enable Network Change in Organizations? A Comparative Study of Feature Use and Shared Affordances by Leonardi, Paul M.

“…The goal of this study is to augment explanations of how newly implemented technologies enable network change within organizations with an understanding of…”
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Automated discovery of chemically reasonable elementary reaction steps by Zimmerman, Paul M.

“…Due to the significant human effort and chemical intuition required to locate chemical reaction pathways with quantum chemical modeling, only a small subspace…”
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Single-ended transition state finding with the growing string method by Zimmerman, Paul M.

“…Reaction path finding and transition state (TS) searching are important tasks in computational chemistry. Methods that seek to optimize an evenly distributed…”
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