Search Results - "Paul, Kiran"
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Analysis of circulating breast cancer cell heterogeneity and interactions with peripheral blood mononuclear cells
Published in Molecular carcinogenesis (01-10-2020)“…For solid tumors, extravasation of cancer cells and their survival in circulation represents a critical stage of the metastatic process that lacks complete…”
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2
Cytokeratin 5 alters β-catenin dynamics in breast cancer cells
Published in Oncogene (01-03-2020)“…Estrogen receptor (ER) positive breast cancers often contain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5). CK5+…”
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3
New generation breast cancer cell lines developed from patient-derived xenografts
Published in Breast cancer research : BCR (23-06-2020)“…Breast cancer is a highly heterogeneous disease characterized by multiple histologic and molecular subtypes. While a myriad of breast cancer cell lines have…”
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4
Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer
Published in British journal of cancer (05-01-2021)“…Background Progesterone receptors (PR) are potent modifiers of endocrine responses. In aberrant signalling cancer contexts, phosphorylation events dramatically…”
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Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Published in BMC biology (10-02-2021)“…The mosquito Anopheles stephensi is a vector of urban malaria in Asia that recently invaded Africa. Studying the genetic basis of vectorial capacity and…”
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Cytokeratins 5 and 17 Maintain an Aggressive Epithelial State in Basal-Like Breast Cancer
Published in Molecular cancer research (02-09-2022)“…Basal-like breast cancers (BLBC) are the most common triple-negative subtype (hormone receptor and HER2 negative) with poor short-term disease outcome and are…”
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7
Neoadjuvant endocrine therapy expands stromal populations that predict poor prognosis in estrogen receptor‐positive breast cancer
Published in Molecular carcinogenesis (01-03-2022)“…The tumor microenvironment (TME) is an important modulator of response and resistance to endocrine therapy in estrogen receptor alpha (ER) positive breast…”
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Degenerate minigene library analysis enables identification of altered branch point utilization by mutant splicing factor 3B1 (SF3B1)
Published in Nucleic acids research (25-01-2019)“…Abstract Cancer-associated mutations of the core splicing factor 3 B1 (SF3B1) result in selection of novel 3′ splice sites (3′SS), but precise molecular…”
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Author Correction: Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Published in BMC biology (02-05-2022)Get full text
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The genome trilogy of Anopheles stephensi, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity
Published in Scientific reports (04-03-2022)“…Anopheles stephensi is the most menacing malaria vector to watch for in newly urbanising parts of the world. Its fitness is reported to be a direct consequence…”
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The Development and Use of Scalable Systems for Studying Aberrant Splicing in SF3B1-Mutant CLL
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Mutational landscape of CLL is now known to include recurrent non-synonymous mutations in SF3B1, a core splicing factor. About 5-10% of newly diagnosed CLL…”
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Abstract 5291: OncoMD: A powerful genomics data analysis and interpretation platform for cancer discovery research
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Cancer cells gain fitness advantage over normal cells by accumulating mutations over time. Next Generation DNA sequencing technologies have made the…”
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13
Estrogens and Progestins Cooperatively Shift Breast Cancer Cell Metabolism
Published in Cancers (31-03-2022)“…Metabolic reprogramming remains largely understudied in relation to hormones in estrogen receptor (ER) and progesterone receptor (PR) positive breast cancer…”
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14
A Near-Chromosome Level Genome Assembly of Anopheles stephensi
Published in Frontiers in genetics (16-11-2020)“…Malaria remains a major healthcare risk to growing economies like India, and a chromosome-level reference genome of is critical for successful vector…”
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Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2)
Published in NAR cancer (01-06-2022)“…Musashi 2 (MSI2) is an RNA binding protein (RBP) that regulates asymmetric cell division and cell fate decisions in normal and cancer stem cells. MSI2 appears…”
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Impact of percutaneous coronary intervention in the right coronary artery on right ventricular function in patients with acute myocardial infarction
Published in Journal of Indian College of Cardiology (01-01-2023)“…Background: Right ventricular (RV) dysfunction is a potent predictor of mortality and morbidity after acute myocardial infarction (MI). Even though elective…”
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Abstract 2605: Cytokeratin 5 promotes endocytosis to remodel cell adhesions in breast cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Breast cancer (BC) is clinically classified according to expression of estrogen receptor, progesterone receptor (ER+ BC), HER2 (HER2+), or absence of…”
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Cloud IoT Based Surveillance System for Tracking and Monitoring of Domestic Animals
Published in 2024 International Conference on Integrated Circuits and Communication Systems (ICICACS) (23-02-2024)“…The global practice of domesticating animals for rearing in residential settings is currently experiencing a significant surge. Animals have become an…”
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Conference Proceeding -
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Cytokeratin 5 alters [beta]-catenin dynamics in breast cancer cells
Published in Oncogene (01-03-2020)“…Estrogen receptor (ER) positive breast cancers often contain subpopulations of cells that express the intermediate filament protein cytokeratin 5 (CK5). CK5+…”
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Is vitamin K2 supplementation effective in reducing fractures in adults?
Published in Evidence-based practice : patient-oriented evidence that matters (03-12-2021)Get full text
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