Search Results - "Paul, Kim"
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Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
Published in Science (American Association for the Advancement of Science) (27-04-2018)“…Activated immune cells undergo a metabolic switch to aerobic glycolysis akin to the Warburg effect, thereby presenting a potential therapeutic target in…”
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Social Determinants of Health Inequities in Indigenous Canadians Through a Life Course Approach to Colonialism and the Residential School System
Published in Health equity (01-01-2019)“…Indigenous populations in Canada have experienced social, economic, and political disadvantages through colonialism. The policies implemented to assimilate…”
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3
Building Reconfigurable Devices Using Complex Liquid–Fluid Interfaces
Published in Advanced materials (Weinheim) (01-05-2019)“…Liquid–fluid interfaces provide a platform both for structuring liquids into complex shapes and assembling dimensionally confined, functional nanomaterials…”
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4
The Orphan Drug Act at 40: Legislative Triumph and the Challenges of Success
Published in The Milbank quarterly (01-03-2024)“…Policy Points The Orphan Drug Act (ODA) was the result of patient advocacy and by many measures has been strikingly successful. However, approximately 95% of…”
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5
Gustilo-Anderson Classification
Published in Clinical orthopaedics and related research (01-11-2012)Get full text
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6
Reconfigurable ferromagnetic liquid droplets
Published in Science (American Association for the Advancement of Science) (19-07-2019)“…Solid ferromagnetic materials are rigid in shape and cannot be reconfigured. Ferrofluids, although reconfigurable, are paramagnetic at room temperature and…”
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The need for accurate D‐dimer reporting in COVID‐19: Communication from the ISTH SSC on fibrinolysis
Published in Journal of thrombosis and haemostasis (01-09-2020)Get full text
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8
Development of an assay to quantify tranexamic acid levels in plasma
Published in Analytical biochemistry (01-02-2025)“…Dysregulations of blood clot breakdown (fibrinolysis) during vascular trauma can lead to excessive blood loss. Tranexamic acid (TXA) is an inhibitor of…”
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Large-Area Atomically Thin MoS2 Nanosheets Prepared Using Electrochemical Exfoliation
Published in ACS nano (22-07-2014)“…Molybdenum disulfide (MoS2) is an extremely intriguing material because of its unique electrical and optical properties. The preparation of large-area and…”
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10
Negative-Pressure Wound Therapy: A Comprehensive Review of the Evidence
Published in Plastic and reconstructive surgery (1963) (01-09-2016)“…Negative-pressure wound therapy (NPWT) and its variations are an established adjunctive modality for the treatment of wounds. Since its introduction, there…”
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Reconstitution of human tissue barrier function for precision and personalized medicine
Published in Lab on a chip (10-07-2024)“…Tissue barriers in a body, well known as tissue-to-tissue interfaces represented by endothelium of the blood vessels or epithelium of organs, are essential for…”
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2018 Frank Stinchfield Award: Spinopelvic Hypermobility Is Associated With an Inferior Outcome After THA: Examining the Effect of Spinal Arthrodesis
Published in Clinical orthopaedics and related research (01-02-2019)“…Many patients undergo both THA and spinal arthrodesis, and those patients may not fare as well as those who undergo one procedure but not the other. The…”
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13
Targeting PKC in microglia to promote remyelination and repair in the CNS
Published in Current opinion in pharmacology (01-02-2022)“…Microglia and CNS-infiltrating macrophages play significant roles in the pathogenesis of neuroinflammatory and neurodegenerative diseases, such as Alzheimer's…”
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14
Effects of Negative-Pressure Wound Therapy With Instillation versus Standard of Care in Multiple Wound Types: Systematic Literature Review and Meta-Analysis
Published in Plastic and reconstructive surgery (1963) (01-01-2021)“…Large randomized controlled trials that evaluate the effects of negative-pressure wound therapy with instillation of a topical solution and dwell time…”
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Introduction to “Soft-Tissue Wound Management: Current Applications of Negative-Pressure Wound Therapy With Instillation”
Published in Plastic and reconstructive surgery (1963) (01-01-2021)Get full text
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16
Chemical and Morphological Control of Interfacial Self‐Doping for Efficient Organic Electronics
Published in Advanced materials (Weinheim) (01-04-2018)“…Solution‐based processing of materials for electrical doping of organic semiconductor interfaces is attractive for boosting the efficiency of organic…”
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Early experience and recommendations for the use of an automated estimator of solution volume for negative pressure wound therapy with instillation
Published in Wounds (King of Prussia, Pa.) (01-02-2023)“…NPWTi is a device that combines the benefits of traditional NPWT with periodic irrigation. This automated device allows for preprogrammed cycles of dwelling of…”
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Pulmonary Embolism Response to Fragmentation, Embolectomy, and Catheter Thrombolysis (PERFECT): Initial Results From a Prospective Multicenter Registry
Published in Chest (01-09-2015)“…Systemic thrombolysis for acute pulmonary embolism (PE) carries up to a 20% risk of major bleeding, including a 2% to 5% risk of hemorrhagic stroke. We…”
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19
Brain proteome-wide association study implicates novel proteins in depression pathogenesis
Published in Nature neuroscience (01-06-2021)“…Depression is a common condition, but current treatments are only effective in a subset of individuals. To identify new treatment targets, we integrated…”
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A specific fluorescence resonance energy quenching–based biosensor for measuring thrombin activity in whole blood
Published in Journal of thrombosis and haemostasis (01-06-2024)“…At sites of vessel injury, thrombin acts as the central mediator of coagulation by catalyzing fibrin clot formation and platelet activation. Thrombin…”
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