Search Results - "Paul, J H"

Innovation, Dynamic Capabilities, and Leadership by Schoemaker, Paul J. H., Heaton, Sohvi, Teece, David

“…The world in which today’s businesses operate has become not only riskier but also more volatile, uncertain, complex, and ambiguous (VUCA). Organizations that…”
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Synthetic Extracellular Matrices with Nonlinear Elasticity Regulate Cellular Organization by Liu, Kaizheng, Mihaila, Silvia M, Rowan, Alan, Oosterwijk, Egbert, Kouwer, Paul H. J

“…One of the promises of synthetic materials in cell culturing is that control over their molecular structures may ultimately be used to control their biological…”
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Cytoskeletal stiffening in synthetic hydrogels by de Almeida, Paula, Jaspers, Maarten, Vaessen, Sarah, Tagit, Oya, Portale, Giuseppe, Rowan, Alan E., Kouwer, Paul H. J.

“…Although common in biology, controlled stiffening of hydrogels in vitro is difficult to achieve; the required stimuli are commonly large and/or the stiffening…”
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Magnetic Stiffening in 3D Cell Culture Matrices by Chen, Wen, Zhang, Ying, Kumari, Jyoti, Engelkamp, Hans, Kouwer, Paul H. J

“…The mechanical environment of a cell is not constant. This dynamic behavior is exceedingly difficult to capture in (synthetic) in vitro matrices. This paper…”
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Multivariate genomic scan implicates novel loci and haem metabolism in human ageing by Timmers, Paul R. H. J., Wilson, James F., Joshi, Peter K., Deelen, Joris

“…Ageing phenotypes, such as years lived in good health (healthspan), total years lived (lifespan), and survival until an exceptional old age (longevity), are of…”
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Responsive biomimetic networks from polyisocyanopeptide hydrogels by Kouwer, Paul H. J., Koepf, Matthieu, Le Sage, Vincent A. A., Jaspers, Maarten, van Buul, Arend M., Eksteen-Akeroyd, Zaskia H., Woltinge, Tim, Schwartz, Erik, Kitto, Heather J., Hoogenboom, Richard, Picken, Stephen J., Nolte, Roeland J. M., Mendes, Eduardo, Rowan, Alan E.

“…Thermal transitions of polyisocyanide single molecules to polymer bundles and finally networks lead to hydrogels mimicking the properties of biopolymer…”
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Crosslinking of fibrous hydrogels by Schoenmakers, Daniël C., Rowan, Alan E., Kouwer, Paul H. J.

“…In contrast to most synthetic hydrogels, biological gels are made of fibrous networks. This architecture gives rise to unique properties, like low…”
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Gradient matters via filament diameter-adjustable 3D printing by Qu, Huawei, Gao, Chongjian, Liu, Kaizheng, Fu, Hongya, Liu, Zhiyuan, Kouwer, Paul H. J., Han, Zhenyu, Ruan, Changshun

“…Gradient matters with hierarchical structures endow the natural world with excellent integrity and diversity. Currently, direct ink writing 3D printing is…”
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Ultra-responsive soft matter from strain-stiffening hydrogels by Jaspers, Maarten, Dennison, Matthew, Mabesoone, Mathijs F. J., MacKintosh, Frederick C., Rowan, Alan E., Kouwer, Paul H. J.

“…The stiffness of hydrogels is crucial for their application. Nature’s hydrogels become stiffer as they are strained. This stiffness is not constant but…”
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The living interface between synthetic biology and biomaterial design by Liu, Allen P., Appel, Eric A., Ashby, Paul D., Baker, Brendon M., Franco, Elisa, Gu, Luo, Haynes, Karmella, Joshi, Neel S., Kloxin, April M., Kouwer, Paul H. J., Mittal, Jeetain, Morsut, Leonardo, Noireaux, Vincent, Parekh, Sapun, Schulman, Rebecca, Tang, Sindy K. Y., Valentine, Megan T., Vega, Sebastián L., Weber, Wilfried, Stephanopoulos, Nicholas, Chaudhuri, Ovijit

“…Recent far-reaching advances in synthetic biology have yielded exciting tools for the creation of new materials. Conversely, advances in the fundamental…”
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Synthesis and Mesomorphic Properties of Rigid-Core Ionic Liquid Crystals by Kouwer, Paul H. J, Swager, Timothy M

“…Ionic liquid crystals combine the unique solvent properties of ionic liquids with self-organization found for liquid crystals. We report a detailed analysis of…”
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Key Developments in Ionic Liquid Crystals by Alvarez Fernandez, Alexandra, Kouwer, Paul H J

“…Ionic liquid crystals are materials that combine the classes of liquid crystals and ionic liquids. The first one is based on the multi-billion-dollar flat…”
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Novel Synthetic Polymer-Based 3D Contraction Assay: A Versatile Preclinical Research Platform for Fibrosis by Kumari, Jyoti, Wagener, Frank A. D. T. G, Kouwer, Paul H. J

“…The driving factors causing fibrosis and scar formation include fibroblast differentiation into myofibroblasts and hampered myofibroblast apoptosis, which…”
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Synthetic fibrous hydrogels as a platform to decipher cell-matrix mechanical interactions by Yuan, Hongbo, Liu, Kaizheng, Cóndor, Mar, Barrasa-Fano, Jorge, Louis, Boris, Vandaele, Johannes, de Almeida, Paula, Coucke, Quinten, Chen, Wen, Oosterwijk, Egbert, Xing, Chengfen, Van Oosterwyck, Hans, Kouwer, Paul H J, Rocha, Susana

“…Cells continuously sense external forces from their microenvironment, the extracellular matrix (ECM). In turn, they generate contractile forces, which stiffen…”
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Tuning Hydrogel Mechanics Using the Hofmeister Effect by Jaspers, Maarten, Rowan, Alan E., Kouwer, Paul H. J.

“…The mechanical properties of hydrogels are commonly modified by changing the concentration of the molecular components. This approach, however, does not only…”
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The Royal College of Ophthalmologists’ National Ophthalmology Database study of cataract surgery: Report 9, Risk factors for posterior capsule opacification by Donachie, Paul H. J., Barnes, Beth L., Olaitan, Martina, Sparrow, John M., Buchan, John C.

“…Background/Objectives Posterior Capsule Opacification (PCO) is the most common long-term post-operative adverse occurrence after cataract surgery often…”
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Adapting to Fast-Changing Markets and Technologies by Day, George S., Schoemaker, Paul J.H.

“…The dynamic capabilities framework identifies three components as critical for successful organizational adaptation: sensing, seizing and transforming. By…”
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Synthetic Extracellular Matrices as a Toolbox to Tune Stem Cell Secretome by Liu, Kaizheng, Veenendaal, Tomas, Wiendels, Maury, Ruiz-Zapata, Alejandra M, van Laar, Justin, Kyranas, Rafail, Enting, Hilde, van Cranenbroek, Bram, Koenen, Hans J. P. M, Mihaila, Silvia M, Oosterwijk, Egbert, Kouwer, Paul H. J

“…The application of stem cell-derived secretome in regenerative therapies offers the key advantage that instead of the stem cells, only their effective…”
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Predicting sepsis-related mortality and ICU admissions from telephone triage information of patients presenting to out-of-hours GP cooperatives with acute infections: A cohort study of linked routine care databases by Loots, Feike J, Smits, Marleen, Jenniskens, Kevin, Leeuwenberg, Artuur M, Giesen, Paul H J, Ramerman, Lotte, Verheij, Robert, van Zanten, Arthur R H, Venekamp, Roderick P

“…General practitioners (GPs) often assess patients with acute infections. It is challenging for GPs to recognize patients needing immediate hospital referral…”
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Nonlinear mechanics of hybrid polymer networks that mimic the complex mechanical environment of cells by Jaspers, Maarten, Vaessen, Sarah L., van Schayik, Pim, Voerman, Dion, Rowan, Alan E., Kouwer, Paul H. J.

“…The mechanical properties of cells and the extracellular environment they reside in are governed by a complex interplay of biopolymers. These biopolymers,…”
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