Search Results - "Paul, Gitendra"

Correlation of Anti-HIV Activity with Anion Spacing in a Series of Cosalane Analogues with Extended Polycarboxylate Pharmacophores by Santhosh, Kalpathy C, Paul, Gitendra C, De Clercq, Erik, Pannecouque, Christophe, Witvrouw, Myriam, Loftus, Tracy L, Turpin, Jim A, Buckheit, Robert W, Cushman, Mark

“…Cosalane and its synthetic derivatives inhibit the binding of gp120 to CD4 as well as the fusion of the viral envelope with the cell membrane. The binding of…”
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Identification of optimal anion spacing for anti-HIV activity in a series of cosalane tetracarboxylates by Paul, Gitendra C, De Clercq, Erik, Pannecouque, Christophe, Witvrouw, Myriam, Loftus, Tracy L, Turpin, Jim A, Buckheit, Robert W, Cushman, Mark

“…The binding of the anti-HIV agent cosalane to CD4 is thought to involve ionic interactions of negatively charged carboxylates of the ligand with positively…”
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Influence of the Geminal Biscyclopropyl Group in the Reactions of Trimethylenemethane:  Reversible Intersystem Crossing by Paul, Gitendra C, Gajewski, Joseph J

“…The azo compound precursor to Berson's trimethylenemethane (TMM) biradical system, 2-methylene-1,3-cyclopentanediyl, was substituted with two cyclopropyl…”
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Conformation of a Geminal Dicyclopropyl-Substituted Trimethylenemethane Triplet [2-(Dicyclopropylmethylidene)cyclopentane-1,3-diyl] by Paul, Gitendra C, Gajewski, Joseph J, Kestyn, Paul A, Khorasanizadeh, Sadaf, Lahti, Paul M

“…Triplet 2-(dicyclopropylmethylidene)cyclopentane-1,3-diyl, CP2TMM, has a Δm s = 2 ESR transition revealing hyperfine splitting consistent with coupling to two…”
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Generation and Characterization of Alkyl-Substituted m-Xylylenes in Fluid Solution at Room Temperature by Gajewski, Joseph J, Paul, Gitendra C, Chang, Ming Jing, Gortva, Andrea M

“…Fluoride ion induced generation of isobutylidene from isopropyl trimethylsilyl ketone enol triflate in the presence of 6,6-dimethylfulvene gives the…”
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Thermal isomerization of a vinylcyclobutene to a cyclohexadiene by Paul, Gitendra C, Gajewski, Joseph J

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Pyrolysis of 9-methylenespiro[3.5]nona-5,7-diene: a route to benzo-2-hexene-1,6-diyl, a putative intermediate in the retro-Diels-Alder reaction of tetralin by Gajewski, Joseph J, Paul, Gitendra C

“…A precursor to the 1,6-biradical potentially formed in the retro-Diels-Alder reaction of tetralin, namely,…”
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An experimental and computational investigation of the mechanism of the deoxygenation of THF by atomic carbon by McKee, Michael L, Paul, Gitendra C, Shevlin, Philip B

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Kinetics of radical-forming homolyses in alkenyl- and tert-butylsilanes. The stability of .alpha.- and .beta.-silicon-substituted alkyl radicals by Davidson, Iain M. T, Barton, Thomas J, Hughes, Kevin J, Ijadi-Maghsoodi, Sina, Revis, Anthony, Paul, Gitendra C

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Silathione (Me2Si:S) extrusion in the thermolysis of silylthioketenes by Barton, Thomas J, Paul, Gitendra C

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o-Benzoquinone methide: an intermediate in the gas-phase pyrolysis of chroman by Paul, Gitendra C, Gajewski, Joseph J

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Photolysis of chloride precursors as a method to prepare and characterize the triplet state of fluorenyl-substituted m-xylylene diradicals by Gajewski, Joseph J., Paul, Gitendra C.

“…Fluorenyl substituted m-xylylene triplet diradicals are conveniently generated from the corresponding dichloride precursors upon photolysis at <100 K in…”
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Extension of the Polyanionic Cosalane Pharmacophore as a Strategy for Increasing Anti-HIV Potency by Cushman, Mark, Insaf, Shabana, Paul, Gitendra, Ruell, Jeffrey A, De Clercq, Erik, Schols, Dominique, Pannecouque, Christophe, Witvrouw, Myriam, Schaeffer, Catherine A, Turpin, Jim A, Williamson, Karen, Rice, William G

“…The anti-HIV agent cosalane inhibits both the binding of gp120 to CD4 as well as an undefined postattachment event prior to reverse transcription. Several…”
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Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds by Howard, O.M.Zack, Dong, Hui Fang, Oppenheim, Joost J., Insaf, Shabana, Santhosh, Kalpathy C., Paul, Gitendra, Cushman, Mark

“…The anti-HIV agent cosalane and several of its analogues inhibited RANTES-induced migration of human monocytes, but they did not inhibit migration induced by…”
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Possible reversible intersystem crossing in a geminal biscyclopropyl substituted m-xylylene by Paul, Gitendra C., Gajewski, Joseph J.

“…Reaction of 6,6-dicyclopropylfulvene with isobutylidene gives rise to products derived from a m-xylylene. Both cyclopropane ring opened monomers with o- and…”
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SYNTHESIS OF 3,6-DI-(tert-BUTYL)FLUORENE BY NICKEL(0) CATALYZED COUPLING OF ARYL HALIDES by Paul, Gitendra C., Gajewski, Joseph J.

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Kinetic and mechanistic aspects of the thermal decomposition of silylketenes, -thioketenes and -ketenimines by Paul, Gitendra Chandra

“…The flash vacuum pyrolysis (FVP) of bis(trimethylsilyl)ketene led to 1-trimethylsilylpropyne and a trace of cyclotrisiloxane. The products were accounted for…”
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Cleavage vs. rearrangement ratios and secondary deuterium kinetic isotope effects in the thermolysis of conformationally fixed cisoid vinylcyclobutanes by Gajewski, J. J, Paul, G. C

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