Search Results - "Paul, Eleanor"

The PCI domains are "winged" HEAT domains by Paul, Eleanor Elise, Marintchev, Assen

“…The HEAT domains are a family of helical hairpin repeat domains, composed of four or more hairpins. HEAT is derived from the names of four family members:…”
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Transcriptional profiling aligned with in situ expression image analysis reveals mosaically expressed molecular markers for GABA neuron sub‐groups in the ventral tegmental area by Paul, Eleanor J., Tossell, Kyoko, Ungless, Mark A.

“…γ‐Aminobutyric acid (GABA) neurons in the ventral tegmental area (VTA) provide local inhibitory control of dopamine neuron activity and send long‐range…”
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Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine by Kokkinou, Michelle, Irvine, Elaine E., Bonsall, David R., Natesan, Sridhar, Wells, Lisa A., Smith, Mark, Glegola, Justyna, Paul, Eleanor J., Tossell, Kyoko, Veronese, Mattia, Khadayate, Sanjay, Dedic, Nina, Hopkins, Seth C., Ungless, Mark A., Withers, Dominic J., Howes, Oliver D.

“…Patients with schizophrenia show increased striatal dopamine synthesis capacity in imaging studies. The mechanism underlying this is unclear but may be due to…”
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Cell-type specialization is encoded by specific chromatin topologies by Winick-Ng, Warren, Kukalev, Alexander, Harabula, Izabela, Zea-Redondo, Luna, Szabó, Dominik, Meijer, Mandy, Serebreni, Leonid, Zhang, Yingnan, Bianco, Simona, Chiariello, Andrea M., Irastorza-Azcarate, Ibai, Thieme, Christoph J., Sparks, Thomas M., Carvalho, Sílvia, Fiorillo, Luca, Musella, Francesco, Irani, Ehsan, Torlai Triglia, Elena, Kolodziejczyk, Aleksandra A., Abentung, Andreas, Apostolova, Galina, Paul, Eleanor J., Franke, Vedran, Kempfer, Rieke, Akalin, Altuna, Teichmann, Sarah A., Dechant, Georg, Ungless, Mark A., Nicodemi, Mario, Welch, Lonnie, Castelo-Branco, Gonçalo, Pombo, Ana

“…The three-dimensional (3D) structure of chromatin is intrinsically associated with gene regulation and cell function 1 – 3 . Methods based on chromatin…”
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Dynamic Interaction Network Involving the Conserved Intrinsically Disordered Regions in Human eIF5 by Marintchev, Assen, Paul, Eleanor E., Lin, Kai Y., Tsai, Amy W‐L, Yang, Yu, Gamble, Nathan, Doran, Matthew

“…Translation initiation in eukaryotes requires multiple eukaryotic translation initiation factors (eIFs) and involves continuous remodeling of the ribosomal…”
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Plasma and cerebrospinal fluid ABeta42 for the differential diagnosis of Alzheimer's disease dementia in participants diagnosed with any dementia subtype in a specialist care setting by Kokkinou, Michelle, Beishon, Lucy C, Smailagic, Nadja, Noel-Storr, Anna H, Hyde, Chris, Ukoumunne, Obioha, Worrall, Rosemary E, Hayen, Anja, Desai, Meera, Ashok, Abhishekh Hulegar, Paul, Eleanor J, Georgopoulou, Aikaterini, Casoli, Tiziana, Quinn, Terry J, Ritchie, Craig W

“…Dementia is a syndrome that comprises many differing pathologies, including Alzheimer's disease dementia (ADD), vascular dementia (VaD) and frontotemporal…”
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Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults by Van de Pette, Mathew, Abbas, Allifia, Feytout, Amelie, McNamara, Gráinne, Bruno, Ludovica, To, Wilson K., Dimond, Andrew, Sardini, Alessandro, Webster, Zoe, McGinty, James, Paul, Eleanor J., Ungless, Mark A., French, Paul M.W., Withers, Dominic J., Uren, Anthony, Ferguson-Smith, Anne C., Merkenschlager, Matthias, John, Rosalind M., Fisher, Amanda G.

“…Imprinted genes are regulated according to parental origin and can influence embryonic growth and metabolism and confer disease susceptibility. Here, we…”
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nNOS-Expressing Neurons in the Ventral Tegmental Area and Substantia Nigra Pars Compacta by Paul, Eleanor J, Kalk, Eliza, Tossell, Kyoko, Irvine, Elaine E, Franks, Nicholas P, Wisden, William, Withers, Dominic J, Leiper, James, Ungless, Mark A

“…GABA neurons in the VTA and SNc play key roles in reward and aversion through their local inhibitory control of dopamine neuron activity and through long-range…”
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Regulation of the interactions between human eIF5 and eIF1A by the CK2 kinase by Gamble, Nathan, Paul, Eleanor Elise, Anand, Bibin, Marintchev, Assen

“…Translation initiation in eukaryotes relies on a complex network of interactions that are continuously reorganized throughout the process. As more information…”
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Biological interaction of living cells with COSAN-based synthetic vesicles by Tarrés, Màrius, Canetta, Elisabetta, Paul, Eleanor, Forbes, Jordan, Azzouni, Karima, Viñas, Clara, Teixidor, Francesc, Harwood, Adrian J.

“…Cobaltabisdicarbollide (COSAN) [3,3′-Co(1,2-C 2 B 9 H 11 ) 2 ] − , is a complex boron-based anion that has the unusual property of self-assembly into membranes…”
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State of the Health-related Quality of Life Evidence in Amyotrophic Lateral Sclerosis (ALS): A Systematic Literature Review (1891) by Paul, Eleanor, Perdrizet, Johnna, Apple, Stephen, Heiman-Patterson, Terry, Holmlund, Tomas, Martin, Markeya, Webb, Lauren, Toor, Kabirraaj

“…Abstract only…”
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Budget impact (BI) analysis of cemiplimab-rwlc for advanced basal cell carcinoma (BCC) after hedgehog inhibitor (HHI) therapy in the United States by Paul, Eleanor, Chen, Chieh-I, Chowdhury, Zahra, Xu, Yingxin, Konidaris, Gerasimos, LaFontaine, Patrick R., Atsou, Kokuvi, Cope, Shannon, Philips, Zoe, Kuznik, Andreas

“…Abstract only e18830 Background: A small proportion of patients (pts) with BCC develop advanced disease (locally advanced [la] and metastatic [m] BCC). Until…”
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Assessing the Value of Cemiplimab for Adults With Advanced Cutaneous Squamous Cell Carcinoma: A Cost-Effectiveness Analysis by Konidaris, Gerasimos, Paul, Eleanor, Kuznik, Andreas, Keeping, Sam, Chen, Chieh-I, Sasane, Medha, Xu, Yingxin, Atsou, Kokuvi, Ayers, Dieter, Ruiz, Emily S., Khushalani, Nikhil I., Cope, Shannon

“…To evaluate the cost-effectiveness of cemiplimab in patients with advanced cutaneous squamous cell carcinoma (CSCC) from a payer perspective in the United…”
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Assessing the value of cemiplimab for adults with advanced cutaneous squamous cell carcinoma (CSCC): A cost-effectiveness analysis by Paul, Eleanor, Kuznik, Andreas, Keeping, Sam, Chen, Chieh-I, Sasane, Medha, Xu, Yingxin, Konidaris, Gerasimos, Atsou, Kokuvi, Ayers, Dieter, Ruiz, Emily S, Khushalani, Nikhil I., Cope, Shannon

“…Abstract only e19397 Background: Cemiplimab is a high-affinity, human, hinge-stabilized, monoclonal antibody that potently blocks the interactions of…”
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Dynamic interaction network involving the conserved intrinsically disordered regions in human eIF5 by Paul, Eleanor Elise, Lin, Kay Ying, Gamble, Nathan, Tsai, Amy Wei-Lun, Swan, Simon H.K., Yang, Yu, Doran, Matthew, Marintchev, Assen

“…Translation initiation in eukaryotes requires multiple eukaryotic translation initiation factors (eIFs) and involves continuous remodeling of the ribosomal…”
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Cost-effectiveness analysis of cemiplimab vs pembrolizumab for treatment of advanced cutaneous squamous cell carcinoma by Paul, Eleanor, Konidaris, Gerasimos, Cope, Shannon, Chen, Chieh-I, Keeping, Sam, Xu, Yingxin, Atsou, Kokuvi, Ayers, Dieter, Guyot, Patricia, Sasane, Medha, Mojebi, Ali, Kuznik, Andreas

“…Most cutaneous squamous cell carcinomas (CSCCs) can be treated with surgical excision or radiation; however, approximately 1% of patients develop advanced…”
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Malignant melanoma of the choroid and ciliary body; a study of 2,535 cases by WILDER, H C, PAUL, E V

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High Cost of Working by Paul, Eleanor J.

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High Cost of Working by Paul, Eleanor J.

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Some observations on the ocular pathology of onchocerciasis by Paul, E V, Zimmerman, L E

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