Search Results - "Paues, J."

Sedimentation rate and suPAR in relation to disease activity and mortality in patients with tuberculosis by Schulman, H., Niward, K., Abate, E., Idh, J., Axenram, P., Bornefall, A., Forsgren, S., Jakobsson, J., öhrling, C., Kron, M., Brudin, L., Diro, E., Getachew Kebede, A., Paues, J., Bruchfeld, J., Wejse, C., Stendahl, O., Schön, T.

“…OBJECTIVE: To investigate how levels of the soluble urokinase plasminogen activator receptor (suPAR) and erythrocyte sedimentation rate (ESR) correlate with…”
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Expression of melanocortin-4 receptor by rat parabrachial neurons responsive to immune and aversive stimuli by Paues, J., Mackerlova, L., Blomqvist, A.

“…The pontine parabrachial nucleus is a major relay area for visceral and other interoceptive information, and has been implicated in mechanisms underlying…”
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Activation of the parabrachio-amygdaloid pathway by immune challenge or spinal nociceptive input: A quantitative study in the rat using Fos immunohistochemistry and retrograde tract tracing by Richard, Sabine, Engblom, David, Paues, Jakob, Mackerlova, Ludmila, Blomqvist, Anders

“…Peripheral nociceptive stimulation results in activation of neurons in the pontine parabrachial nucleus (PB) of rats. Electrophysiological studies have…”
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Population Pharmacokinetics and Dose Evaluation of Cycloserine among Patients with Multidrug-Resistant Tuberculosis under Standardized Treatment Regimens by Zhu, Yue, Zhu, Limei, Davies Forsman, Lina, Paues, Jakob, Werngren, Jim, Niward, Katarina, Schön, Thomas, Bruchfeld, Judith, Xiong, Haiyan, Alffenaar, Jan-Willem, Hu, Yi

“…Although cycloserine is a recommended drug for the treatment of multidrug-resistant tuberculosis (MDR-TB) according to World Health Organization (WHO), few…”
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Development and validation of a simple LC-MS/MS method for simultaneous determination of moxifloxacin, levofloxacin, prothionamide, pyrazinamide and ethambutol in human plasma by Zheng, Xubin, Jongedijk, Erwin M., Hu, Yi, Kuhlin, Johanna, Zheng, Rongrong, Niward, Katarina, Paues, Jakob, Xu, Biao, Davies Forsman, Lina, Schön, Thomas, Bruchfeld, Judith, Alffenaar, Jan-Willem C.

“…•Five antituberculosis drugs are simultaneously determined in plasma by LC-MS/MS.•Analytes are moxifloxacin, levofloxacin, prothionamide, pyrazinamide and…”
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Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China by Davies Forsman, Lina, Niward, Katarina, Kuhlin, Johanna, Zheng, Xubin, Zheng, Rongrong, Ke, Ran, Hong, Chao, Werngren, Jim, Paues, Jakob, Simonsson, Ulrika S H, Eliasson, Erik, Hoffner, Sven, Xu, Biao, Alffenaar, Jan-Willem, Schön, Thomas, Hu, Yi, Bruchfeld, Judith

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Individualised dosing algorithm and personalised treatment of high‐dose rifampicin for tuberculosis by Svensson, Robin J., Niward, Katarina, Davies Forsman, Lina, Bruchfeld, Judith, Paues, Jakob, Eliasson, Erik, Schön, Thomas, Simonsson, Ulrika S.H.

“…Aims To propose new exposure targets for Bayesian dose optimisation suited for high‐dose rifampicin and to apply them using measured plasma concentrations…”
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Distribution of plasma concentrations of first-line anti-TB drugs and individual MICs: a prospective cohort study in a low endemic setting by Niward, Katarina, Davies Forsman, Lina, Bruchfeld, Judith, Chryssanthou, Erja, Carlström, Oskar, Alomari, Teba, Carlsson, Björn, Pohanka, Anton, Mansjö, Mikael, Jonsson Nordvall, Michaela, Johansson, Anders G, Eliasson, Erik, Werngren, Jim, Paues, Jakob, Simonsson, Ulrika S H, Schön, Thomas

“…Therapeutic drug monitoring (TDM) could improve current TB treatment, but few studies have reported pharmacokinetic data together with MICs. To investigate…”
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Population pharmacokinetics and dose evaluations of linezolid in the treatment of multidrug-resistant tuberculosis by Zhang, Haoyue, He, Yuying, Davies Forsman, Lina, Paues, Jakob, Werngren, Jim, Niward, Katarina, Schön, Thomas, Bruchfeld, Judith, Alffenaar, Jan-Willem, Hu, Yi

“…The pharmacokinetic/pharmacodynamics (PK/PD) target derived from the hollow-fiber system model for linezolid for treatment of the multidrug-resistant…”
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Population pharmacokinetics and model-based dosing evaluation of bedaquiline in multidrug-resistant tuberculosis patients by Shao, Ge, Bao, Ziwei, Davies Forsman, Lina, Paues, Jakob, Werngren, Jim, Niward, Katarina, Schön, Thomas, Bruchfeld, Judith, Alffenaar, Jan-Willem, Hu, Yi

“…Bedaquiline is now recommended to all patients in the treatment of multidrug-resistant tuberculosis (MDR-TB) using standard dosing regimens. As the ability to…”
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Plasma Levels of Rifampin Correlate with the Tuberculosis Drug Activity Assay by Niward, Katarina, Ek Blom, Linnea, Davies Forsman, Lina, Bruchfeld, Judith, Eliasson, Erik, Schön, Thomas, Chryssanthou, Erja, Paues, Jakob

“…The plasma tuberculosis drug activity (TDA) assay may be an alternative tool for therapeutic drug monitoring in resource-limited settings. In tuberculosis (TB)…”
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Susceptibility testing breakpoints for Mycobacterium tuberculosis categorize isolates with resistance mutations in gyrA as susceptible to fluoroquinolones: implications for MDR-TB treatment and the definition of XDR-TB by Niward, Katarina, Ängeby, Kristian, Chryssanthou, Erja, Paues, Jakob, Bruchfeld, Judith, Jureen, Pontus, Giske, Christian G, Kahlmeter, Gunnar, Schön, Thomas

“…Fluoroquinolones (FQs) are important in the treatment of MDR-TB and in the definition of XDR-TB. Our objective was to investigate how discrepancies in the…”
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Plasma concentrations of second-line antituberculosis drugs in relation to minimum inhibitory concentrations in multidrug-resistant tuberculosis patients in China: a study protocol of a prospective observational cohort study by Davies Forsman, Lina, Niward, Katarina, Hu, Yi, Zheng, Rongrong, Zheng, Xubin, Ke, Ran, Cai, Weiping, Hong, Chao, Li, Yang, Gao, Yazhou, Werngren, Jim, Paues, Jakob, Kuhlin, Johanna, Simonsson, Ulrika S H, Eliasson, Erik, Alffenaar, Jan-Willem, Mansjö, Mikael, Hoffner, Sven, Xu, Biao, Schön, Thomas, Bruchfeld, Judith

“…IntroductionIndividualised treatment through therapeutic drug monitoring (TDM) may improve tuberculosis (TB) treatment outcomes but is not routinely…”
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Feeding-related immune responsive brain stem neurons: association with CGRP by Paues, Jakob, Engblom, David, Mackerlova, Ludmila, Ericsson-Dahlstrand, Anders, Blomqvist, Anders

“…Using dual-labeling in situ hybridization histochemistry, the neurotransmitter expression of immune-responsive neurons in the pontine parabrachial nucleus, a…”
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Preproenkephalin mRNA expression in rat parabrachial neurons: relation to cells activated by systemic immune challenge by Engström, Linda, Engblom, David, Örtegren, Unn, Mackerlova, Ludmila, Paues, Jakob, Blomqvist, Anders

“…By using a dual-labeling immunohistochemical/in situ hybridization technique we examined if enkephalin-expressing neurons in the pontine parabrachial nucleus,…”
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