Search Results - "Paudel, Sunita S"
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Transcriptional profiles of pulmonary artery endothelial cells in pulmonary hypertension
Published in Scientific reports (18-12-2023)“…Pulmonary arterial hypertension (PAH) is characterized by endothelial cell (EC) dysfunction. There are no data from living patients to inform whether…”
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Endothelial metabolism in pulmonary vascular homeostasis and acute respiratory distress syndrome
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2021)“…Capillary endothelial cells possess a specialized metabolism necessary to adapt to the unique alveolar-capillary environment. Here, we highlight how…”
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KD025 Shifts Pulmonary Endothelial Cell Bioenergetics and Decreases Baseline Lung Permeability
Published in American journal of respiratory cell and molecular biology (01-10-2020)“…KD025 is a ROCK2 inhibitor currently being tested in clinical trials for the treatment of fibrotic lung diseases. The therapeutic effects of KD025 are partly…”
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Carbonic anhydrase IX proteoglycan-like and intracellular domains mediate pulmonary microvascular endothelial cell repair and angiogenesis
Published in American journal of physiology. Lung cellular and molecular physiology (01-07-2022)“…The lungs of patients with acute respiratory distress syndrome (ARDS) have hyperpermeable capillaries that must undergo repair in an acidic microenvironment…”
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Integrative Toolkit to Analyze Cellular Signals: Forces, Motion, Morphology, and Fluorescence
Published in Journal of visualized experiments (05-03-2022)“…Quantitative assessment of cellular forces and motion advanced considerably over the last four decades. These advancements provided the framework to examine…”
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Human YRNA 4 (HY4) plasma levels are a prognostic indicator of SARS-CoV-2 infection clinical severity
Published in microPublication biology (01-01-2023)“…SARS-CoV-2 infection can result in a range of outcomes from asymptomatic/mild disease to severe COVID-19/fatality. In this study, we investigated the…”
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