Search Results - "Paudel, K."

Prevalence, associated factors, awareness, treatment, and control of hypertension: Findings from a cross sectional study conducted as a part of a community based intervention trial in Surkhet, Mid-western region of Nepal by Khanal, Mahesh Kumar, Dhungana, Raja Ram, Bhandari, Pratiksha, Gurung, Yadav, Paudel, K N

“…Hypertension is one of the leading public health problems globally. About half of the deaths from cardiovascular diseases were attributed to hypertension in…”
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Effectiveness of community-based health education and home support program to reduce blood pressure among patients with uncontrolled hypertension in Nepal: A cluster-randomized trial by Khanal, Mahesh Kumar, Bhandari, Pratiksha, Dhungana, Raja Ram, Bhandari, Pratik, Rawal, Lal B, Gurung, Yadav, Paudel, K N, Singh, Amit, Devkota, Surya, Courten, Barbora de

“…Hypertension is a major global public health problem. Elevated blood pressure can cause cardiovascular and kidney diseases. We assessed the effectiveness of…”
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14-3-3ζ Mediates Tau Aggregation in Human Neuroblastoma M17 Cells by Li, Tong, Paudel, Hemant K

“…Microtubule-associated protein tau is the major component of paired helical filaments (PHFs) associated with the neuropathology of Alzheimer's disease (AD)…”
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How small communities respond to environmental change: patterns from tropical to polar ecosystems by Huntington, Henry P., Begossi, Alpina, Gearheard, Shari Fox, Kersey, Beth, Loring, Philip A., Mustonen, Tero, Paudel, Prakash K., Silvano, Renato A. M., Vave, Ron

“…Local communities throughout the world are experiencing extensive social, cultural, economic, environmental, and climatic changes. Rather than passively…”
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Amyloid β peptide promotes lysosomal degradation of clusterin via sortilin in hippocampal primary neurons by Wang, Yunling, Qin, Xike, Paudel, Hemant K

“…Abstract Progressive accumulation of amyloid-β peptide (Aβ) in the brain is implicated as the central event in the development of Alzheimer's disease (AD). It…”
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Development and validation of a salivary tau biomarker in Alzheimer's disease by Pekeles, Heather, Qureshi, Hamid Y., Paudel, Hemant K., Schipper, Hyman M., Gornistky, Mervyn, Chertkow, Howard

“…Total tau (t-tau) and phosphorylated tau (p-tau) are abnormally elevated in the brain and cerebrospinal fluid of individuals with Alzheimer's disease (AD). Tau…”
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The impact of time at home on potential yield of home-based TB contact investigation by Paudel, K., Nalutaaya, A., Robsky, K. O., Kitonsa, P. J., Nakasolya, O., Mukiibi, J., Isooba, D., Kendall, E. A., Katamba, A., Dowdy, D.

“…BACKGROUND: The yield of TB contact tracing is often limited by challenges in reaching individuals during the screening process. We investigated the times at…”
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Rescue and rehabilitation capacity needed to save live pangolins seized from illegal wildlife trade in Nepal by Paudel, K., Bashyal, R., Pokheral, C. P., Kaspal, P., Karki, B. K., Khatiwada, A. P.

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Trends, patterns, and networks of illicit wildlife trade in Nepal: A national synthesis by Paudel, Prakash K., Acharya, Krishna Prasad, Baral, Hem Sagar, Heinen, Joel T., Jnawali, Shant Raj

“…Illicit wildlife trade may have devastating consequences for Nepal's wildlife populations given its increasing national and global connectivity and proximity…”
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Technical and scale efficiencies of meat goat farms in the USA by Qushim, B., Gillespie, J., Paudel, K., Mcmillin, K.

“…This study determines i) scale and technical efficiencies, ii) marginal productive contributions for inputs and outputs and iii) efficiency drivers of meat…”
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Cyclin-Dependent Protein Kinase 5 Primes Microtubule-Associated Protein Tau Site-Specifically for Glycogen Synthase Kinase 3β by Li, Tong, Hawkes, Cheryl, Qureshi, Hamid Y, Kar, Satyabrata, Paudel, Hemant K

“…In the preceding paper, we showed that GSK3β phosphorylates tau at S202, T231, S396, and S400 in vivo. Phosphorylation of S202 occurs without priming…”
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Over-expression of heme oxygenase-1 promotes oxidative mitochondrial damage in rat astroglia by Song, Wei, Su, Haixiang, Song, Sisi, Paudel, Hemant K., Schipper, Hyman M.

“…Glial heme oxygenase‐1 is over‐expressed in the CNS of subjects with Alzheimer disease (AD), Parkinson disease (PD) and multiple sclerosis (MS). Up‐regulation…”
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Phosphorylation of Protein Phosphatase 1 by Cyclin-dependent Protein Kinase 5 during Nerve Growth Factor-induced PC12 Cell Differentiation by Li, Tong, Chalifour, Lorraine E., Paudel, Hemant K.

“…The transcription factor Egr-1 activates cyclin-dependent protein kinase 5 (Cdk5) during nerve growth factor (NGF)-induced differentiation of PC12 cells into…”
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Prevalence of Early Marriage and Its Underlying Causes in Nepal: A Mixed Methods Study by Bhattarai, Prakash C., Paudel, Deepak R., Poudel, Tikaram, Gautam, Suresh, Paudel, Prakash K., Shrestha, Milan, Ginting, Janes I., Ghimire, Dhruba R.

“…Early marriage is one of the major traditional practices that affects the life of both boys and girls in many different ways. In this context, this research…”
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Small-Molecule Bulk Heterojunctions: Distinguishing Between Effects of Energy Offsets and Molecular Packing on Optoelectronic Properties by Paudel, K, Johnson, B, Neunzert, A, Thieme, M, Purushothaman, B, Payne, M. M, Anthony, J. E, Ostroverkhova, O

“…We report on the dependence of time-resolved photoluminescence (PL) and photocurrent in small-molecule bulk heterojunctions on the donor–acceptor (D/A) LUMO…”
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Tuning Intermolecular Interactions in Dioctyl-Substituted Polyfluorene via Hydrostatic Pressure by Paudel, K, Knoll, H, Chandrasekhar, M, Guha, S

“…Polyfluorenes (PFs) represent a unique class of poly-para-phenylene-based blue-emitting polymers with intriguing structure−property relationships. Slight…”
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ABSTRACT OF THE YEAR Histological analysis of gastric ghrelin expression in selective bariatric embolized swine by Fu, Y, Paudel, K, Kedziorek, D, Robert, A, Krimins, R, Weiss, C, Kraitchman, D

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14-3-3ζ Is an Effector of Tau Protein Phosphorylation by Hashiguchi, Mitsuko, Sobue, Kazuya, Paudel, Hemant K.

“…Neurofibrillary tangles associated with Alzheimer's disease are composed mainly of paired helical filaments that are formed by the aggregation of abnormally…”
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Cystatin C promotes tau protein phosphorylation and causes microtubule instability by inhibiting intracellular turnover of GSK3β in neurons by Duan, Jinhai, Marcellus, Kristen A., Qin, Xike, Wang, Yunling, Paudel, Hemant K.

“…In Alzheimer's disease (AD) tau protein hyperphosphorylation causes neurofibrillary tangle formation, microtubule instability and neurodegeneration…”
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14-3-3 connects glycogen synthase kinase-3 beta to tau within a brain microtubule-associated tau phosphorylation complex by Agarwal-Mawal, Alka, Qureshi, Hamid Y, Cafferty, Patrick W, Yuan, Zongfei, Han, Dong, Lin, Rongtian, Paudel, Hemant K

“…In a recent study, we reported that in bovine brain extract, glycogen synthase kinase-3beta and tau are parts of an approximately 400-500 kDa…”
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