Search Results - "Pau, Maria Grazia"

A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates by Callendret, Benoit, Vellinga, Jort, Wunderlich, Kerstin, Rodriguez, Ariane, Steigerwald, Robin, Dirmeier, Ulrike, Cheminay, Cedric, Volkmann, Ariane, Brasel, Trevor, Carrion, Ricardo, Giavedoni, Luis D, Patterson, Jean L, Mire, Chad E, Geisbert, Thomas W, Hooper, Jay W, Weijtens, Mo, Hartkoorn-Pasma, Jutta, Custers, Jerome, Grazia Pau, Maria, Schuitemaker, Hanneke, Zahn, Roland

“…The search for a universal filovirus vaccine that provides protection against multiple filovirus species has been prompted by sporadic but highly lethal…”
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Recombinant Adenovirus Serotype 26 (Ad26) and Ad35 Vaccine Vectors Bypass Immunity to Ad5 and Protect Nonhuman Primates against Ebolavirus Challenge by GEISBERT, Thomas W, BAILEY, Michael, CUSTERS, Jerome, VELLINGA, Jort, HENDRIKS, Jenny, JAHRLING, Peter, ROEDERER, Mario, GOUDSMIT, Jaap, KOUP, Richard, SULLIVAN, Nancy J, HENSLEY, Lisa, ASIEDU, Clement, GEISBERT, Joan, STANLEY, Daphne, HONKO, Anna, JOHNSON, Joshua, MULANGU, Sabue, GRAZIA PAU, Maria

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Ad35 and ad26 vaccine vectors induce potent and cross-reactive antibody and T-cell responses to multiple filovirus species by Zahn, Roland, Gillisen, Gert, Roos, Anna, Koning, Marina, van der Helm, Esmeralda, Spek, Dirk, Weijtens, Mo, Grazia Pau, Maria, Radošević, Katarina, Weverling, Gerrit Jan, Custers, Jerome, Vellinga, Jort, Schuitemaker, Hanneke, Goudsmit, Jaap, Rodríguez, Ariane

“…Filoviruses cause sporadic but highly lethal outbreaks of hemorrhagic fever in Africa in the human population. Currently, no drug or vaccine is available for…”
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Correction: A prophylactic multivalent vaccine against different filovirus species is immunogenic and provides protection from lethal infections with Ebolavirus and Marburgvirus species in non-human primates by Callendret, Benoit, Vellinga, Jort, Wunderlich, Kerstin, Rodriguez, Ariane, Steigerwald, Robin, Dirmeier, Ulrike, Cheminay, Cedric, Volkmann, Ariane, Brasel, Trevor, Carrion, Ricardo, Giavedoni, Luis D, Patterson, Jean L, Mire, Chad E, Geisbert, Thomas W, Hooper, Jay W, Weijtens, Mo, Hartkoorn-Pasma, Jutta, Custers, Jerome, Grazia Pau, Maria, Schuitemaker, Hanneke, Zahn, Roland

“…[This corrects the article DOI: 10.1371/journal.pone.0192312.]…”
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Ad35.CS.01-RTS,S/AS01 Heterologous Prime Boost Vaccine Efficacy against Sporozoite Challenge in Healthy Malaria-Naïve Adults by Ockenhouse, Christian F, Regules, Jason, Tosh, Donna, Cowden, Jessica, Kathcart, April, Cummings, James, Paolino, Kristopher, Moon, James, Komisar, Jack, Kamau, Edwin, Oliver, Thomas, Chhoeu, Austin, Murphy, Jitta, Lyke, Kirsten, Laurens, Matthew, Birkett, Ashley, Lee, Cynthia, Weltzin, Rich, Wille-Reece, Ulrike, Sedegah, Martha, Hendriks, Jenny, Versteege, Isabella, Pau, Maria Grazia, Sadoff, Jerold, Vanloubbeeck, Yannick, Lievens, Marc, Heerwegh, Dirk, Moris, Philippe, Guerra Mendoza, Yolanda, Jongert, Erik, Cohen, Joe, Voss, Gerald, Ballou, W Ripley, Vekemans, Johan

“…In an observer blind, phase 2 trial, 55 adults were randomized to receive one dose of Ad35.CS.01 vaccine followed by two doses of RTS,S/AS01 (ARR-group) or…”
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Persistence of immunological memory as a potential correlate of long-term, vaccine-induced protection against Ebola virus disease in humans by McLean, Chelsea, Dijkman, Karin, Gaddah, Auguste, Keshinro, Babajide, Katwere, Michael, Douoguih, Macaya, Robinson, Cynthia, Solforosi, Laura, Czapska-Casey, Dominika, Dekking, Liesbeth, Wollmann, Yvonne, Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Sadoff, Jerry, Schuitemaker, Hanneke, Zahn, Roland, Luhn, Kerstin, Hendriks, Jenny, Roozendaal, Ramon

“…In the absence of clinical efficacy data, vaccine protective effect can be extrapolated from animals to humans, using an immunological biomarker in humans that…”
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Protection against Marburg Virus and Sudan Virus in NHP by an Adenovector-Based Trivalent Vaccine Regimen Is Correlated to Humoral Immune Response Levels by Tiemessen, Machteld M, Solforosi, Laura, Dekking, Liesbeth, Czapska-Casey, Dominika, Serroyen, Jan, Sullivan, Nancy J, Volkmann, Ariane, Pau, Maria Grazia, Callendret, Benoit, Schuitemaker, Hanneke, Luhn, Kerstin, Zahn, Roland, Roozendaal, Ramon

“…The Marburg virus (MARV) and Sudan virus (SUDV) belong to the filovirus family. The sporadic human outbreaks occur mostly in Africa and are characterized by an…”
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Vector Choice Determines Immunogenicity and Potency of Genetic Vaccines against Angola Marburg Virus in Nonhuman Primates by GEISBERT, Thomas W, BAILEY, Michael, SULLIVAN, Nancy J, GEISBERT, Joan B, ASIEDU, Clement, ROEDERER, Mario, GRAZIA-PAU, Maria, CUSTERS, Jerome, JAHRLING, Peter, GOUDSMIT, Jaap, KOUP, Richard

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A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated Healthy Adults by Sheehan, Sharon, Harris, Stephanie A, Satti, Iman, Hokey, David A, Dheenadhayalan, Veerabadran, Stockdale, Lisa, Manjaly Thomas, Zita-Rose, Minhinnick, Alice, Wilkie, Morven, Vermaak, Samantha, Meyer, Joel, O'Shea, Matthew K, Pau, Maria Grazia, Versteege, Isabella, Douoguih, Macaya, Hendriks, Jenny, Sadoff, Jerald, Landry, Bernard, Moss, Paul, McShane, Helen

“…MVA85A and AERAS-402 are two clinically advanced viral vectored TB vaccine candidates expressing Mycobacterium tuberculosis antigens designed to boost…”
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Towards Novel HIV-1 Serodiagnostic Tests without Vaccine-Induced Seroreactivity by Lagatie, Ole, Lauwers, Dax, Singh, Harvinder, Vanroye, Fien, Stieh, Daniel J, Vingerhoets, Johan, Lavreys, Ludo, Oriol-Mathieu, Valérie, Colón, Will, Verhofstede, Chris, Vercauteren, Koen, Van den Bossche, Dorien, Pau, Maria Grazia

“…Vaccine-induced seroreactivity/positivity (VISR/P) poses a significant and common challenge to HIV vaccine implementation, as up to 95% of vaccine recipients…”
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A phase 1b randomized, controlled, double-blinded dosage-escalation trial to evaluate the safety, reactogenicity and immunogenicity of an adenovirus type 35 based circumsporozoite malaria vaccine in Burkinabe healthy adults 18 to 45 years of age by Ouédraogo, Alphonse, Tiono, Alfred B, Kargougou, Désiré, Yaro, Jean Baptiste, Ouédraogo, Esperance, Kaboré, Youssouf, Kangoye, David, Bougouma, Edith C, Gansane, Adama, Henri, Noelie, Diarra, Amidou, Sanon, Souleymane, Soulama, Issiaka, Konate, Amadou T, Watson, Nora L, Brown, Valerie, Hendriks, Jenny, Pau, Maria Grazia, Versteege, Isabella, Wiesken, Edison, Sadoff, Jerald, Nebie, Issa, Sirima, Sodiomon B

“…Ad35.CS.01 is a pre-erythrocytic malaria candidate vaccine. It is a codon optimized nucleotide sequence representing the P. falciparum circumsporozoite (CS)…”
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Genetic immunization in the lung induces potent local and systemic immune responses by Song, Kaimei, Bolton, Diane L., Wilson, Robert L., Camp, Jeremy V., Bao, Saran, Mattapallil, Joseph J., Herzenberg, Leonore A., Herzenberg, Leonard A., Andrews, Charla A., Sadoff, Jerald C., Goudsmit, Jaap, Pau, Maria Grazia, Seder, Robert A., Kozlowski, Pamela A., Nabel, Gary J., Roederer, Mario, Rao, Srinivas S.

“…Successful vaccination against respiratory infections requires elicitation of high levels of potent and durable humoral and cellular responses in the lower…”
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rBCG induces strong antigen-specific T cell responses in rhesus macaques in a prime-boost setting with an adenovirus 35 tuberculosis vaccine vector by Magalhaes, Isabelle, Sizemore, Donata R, Ahmed, Raija K, Mueller, Stefanie, Wehlin, Lena, Scanga, Charles, Weichold, Frank, Schirru, Giulia, Pau, Maria Grazia, Goudsmit, Jaap, Kühlmann-Berenzon, Sharon, Spångberg, Mats, Andersson, Jan, Gaines, Hans, Thorstensson, Rigmor, Skeiky, Yasir A W, Sadoff, Jerry, Maeurer, Markus

“…BCG vaccination, combined with adenoviral-delivered boosts, represents a reasonable strategy to augment, broaden and prolong immune protection against…”
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An alternative to the adenovirus inverted terminal repeat sequence increases the viral genome replication rate and provides a selective advantage in vitro by Wunderlich, Kerstin, van der Helm, Esmeralda, Spek, Dirk, Vermeulen, Mark, Gecgel, Adile, Pau, Maria Grazia, Vellinga, Jort, Custers, Jerome

“…During the development of human adenovirus 35-derived replication-incompetent (rAd35) vaccine vectors for prevention of infectious diseases, we detected…”
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The Th1 Immune Response to Plasmodium falciparum Circumsporozoite Protein Is Boosted by Adenovirus Vectors 35 and 26 with a Homologous Insert by Radosevic, Katarina, Rodriguez, Ariane, Lemckert, Angelique A C, van der Meer, Marjolein, Gillissen, Gert, Warnar, Carolien, von Eyben, Rie, Pau, Maria Grazia, Goudsmit, Jaap

“…ERRATUM ( vol. 18 , p. 353 ) Classifications Services CVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Evaluation of a prime-boost vaccine schedule with distinct adenovirus vectors against malaria in rhesus monkeys by Rodríguez, Ariane, Mintardjo, Ratna, Tax, Dennis, Gillissen, Gert, Custers, Jerome, Pau, Maria Grazia, Klap, Jaco, Santra, Sampa, Balachandran, Harikrishnan, Letvin, Norman L, Goudsmit, Jaap, Radošević, Katarina

“…Abstract A vaccine that elicits both specific antibodies and IFN-γ-producing T cells is required to protect against pre-erythrocytic malaria. Among the most…”
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Randomized, placebo-controlled trial to assess the safety and immunogenicity of an adenovirus type 35-based circumsporozoite malaria vaccine in healthy adults by Creech, C Buddy, Dekker, Cornelia L, Ho, Dora, Phillips, Shanda, Mackey, Sally, Murray-Krezan, Cristina, Grazia Pau, Maria, Hendriks, Jenny, Brown, Valerie, Dally, Leonard G, Versteege, Isabella, Edwards, Kathryn M

“…Malaria results in over 650 000 deaths each year; thus, there is an urgent need for an effective vaccine. Pre-clinical studies and recently reported human…”
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A Peptide-Based Plasmodium falciparum Circumsporozoite Assay To Test for Serum Antibody Responses to Pre-Erythrocyte Malaria Vaccines by Kostense, Stefan, Mommaas, Bregje, Hendriks, Jenny, Verhoeven, Mariëlle, Ter Haak, Mariska, Tirion, Felicia, Wiesken, Edison, Pau, Maria Grazia, Radosevic, Katarina, Goudsmit, Jaap

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Safety and Immunogenicity of Novel Adenovirus Type 26– and Modified Vaccinia Ankara–Vectored Ebola Vaccines: A Randomized Clinical Trial by Milligan, Iain D, Gibani, Malick M, Sewell, Richard, Clutterbuck, Elizabeth A, Campbell, Danielle, Plested, Emma, Nuthall, Elizabeth, Voysey, Merryn, Silva-Reyes, Laura, McElrath, M. Juliana, De Rosa, Stephen C, Frahm, Nicole, Cohen, Kristen W, Shukarev, Georgi, Orzabal, Nicola, van Duijnhoven, Wilbert, Truyers, Carla, Bachmayer, Nora, Splinter, Daniel, Samy, Nathaly, Pau, Maria Grazia, Schuitemaker, Hanneke, Luhn, Kerstin, Callendret, Benoit, Van Hoof, Johan, Douoguih, Macaya, Ewer, Katie, Angus, Brian, Pollard, Andrew J, Snape, Matthew D

“…IMPORTANCE: Developing effective vaccines against Ebola virus is a global priority. OBJECTIVE: To evaluate an adenovirus type 26 vector vaccine encoding Ebola…”
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HIV Diagnostics and Vaccines: It Takes Two to Tango by Colón, Will, Oriol-Mathieu, Valérie, Hural, John, Hattingh, Lucy, Adungo, Ferdinard, Lagatie, Ole, Lavreys, Ludo, Allen, Mary, Anzala, Omu, Espy, Nicole, Fransen, Katrien, Garcia, Patricia J, Maciel, Jr, Milton, Murtagh, Maurine, Peel, Sheila A, Peeling, Rosanna W, Tan, Litjen L J, Warren, Mitchell, Pau, Maria Grazia, D'Souza, Patricia M

“…Current serologic tests for HIV screening and confirmation of infection present challenges to the adoption of HIV vaccines. The detection of vaccine-induced…”
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