Search Results - "Patton, Amy L"
-
1
K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure
Published in Journal of forensic sciences (01-11-2013)“…Limited forensic and clinical experience and the lack of confirmatory testing strategies for synthetic cannabinoids (SC) prevent adequate characterization of…”
Get full text
Journal Article -
2
Forensic investigation of K2, Spice, and “bath salt” commercial preparations: A three-year study of new designer drug products containing synthetic cannabinoid, stimulant, and hallucinogenic compounds
Published in Forensic science international (10-12-2013)“…Abstract New designer drugs such as K2, Spice, and “bath salts” present a formidable challenge for law enforcement and public health officials. The following…”
Get full text
Journal Article -
3
Quantitative Measurement of Acetyl Fentanyl and Acetyl Norfentanyl in Human Urine by LC-MS/MS
Published in Analytical chemistry (Washington) (04-02-2014)“…Opioid abuse involving emerging opioid compounds is a growing public health problem, which was highlighted recently by cases of human morbidity and mortality…”
Get full text
Journal Article -
4
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ9-THC
Published in Frontiers in pharmacology (26-09-2018)“…Recreational use of marijuana is associated with few adverse effects, but abuse of synthetic cannabinoids (SCBs) can result in anxiety, psychosis, chest pain,…”
Get full text
Journal Article -
5
Modification of a liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) method targeting lysergic acid diethylamide (LSD) and its primary metabolite (OH‐LSD) to include nine LSD analogs
Published in Journal of forensic sciences (01-09-2024)“…A variety of LSD analogs have emerged in recent years with dual purposes of avoiding prosecution from possession while providing new options for those willing…”
Get full text
Journal Article -
6
2421 Development and validation of a translational rat model of neonatal abstinence syndrome
Published in Journal of clinical and translational science (01-06-2018)“…OBJECTIVES/SPECIFIC AIMS: Rodent models can be used to study neonatal abstinence syndrome (NAS), but the applicability of findings from the models to NAS in…”
Get full text
Journal Article -
7
Quantitative Analysis of Lysergic Acid Diethylamide and Metabolite in Urine by Automated Extraction and Liquid Chromatography–Tandem Mass Spectrometry
Published in Journal of analytical toxicology (19-05-2023)“…Abstract Recently, lysergic acid diethylamide (LSD) has become a resurgent drug of abuse. The detection of LSD is problematic because of the low dosage taken…”
Get full text
Journal Article -
8
Cross-reactivity of 24 cannabinoids and metabolites in blood using the Immunalysis Cannabinoids Direct enzyme-linked immunosorbent assay
Published in Journal of analytical toxicology (13-07-2024)“…With wider availability of synthetic and semi-synthetic cannabinoids in the consumer space, there is a growing impact on public health and safety. Forensic…”
Get full text
Journal Article -
9
Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants
Published in Biochemical and biophysical research communications (06-04-2018)“…Synthetic cannabinoids (SCBs), synonymous with ‘K2’, ‘Spice’ or ‘synthetic marijuana’, are psychoactive drugs of abuse that frequently result in clinical…”
Get full text
Journal Article -
10
In Utero Exposure to Norbuprenorphine, a Major Metabolite of Buprenorphine, Induces Fetal Opioid Dependence and Leads to Neonatal Opioid Withdrawal Syndrome
Published in The Journal of pharmacology and experimental therapeutics (01-07-2019)“…Buprenorphine is the preferred treatment of opioid use disorder during pregnancy but can cause fetal opioid dependence and neonatal opioid withdrawal syndrome…”
Get more information
Journal Article -
11
The Spice of Death: Sudden Cardiac Arrest After Novel Psychoactive Substance Exposure
Published in Pediatric emergency care (01-01-2022)“…Novel psychoactive substances (NPSs), commonly referred to as "K2" or "spice," are a relatively new toxicology challenge for pediatricians. Adolescents often…”
Get full text
Journal Article -
12
Targeted Metabolomic Approach for Assessing Human Synthetic Cannabinoid Exposure and Pharmacology
Published in Analytical chemistry (Washington) (01-10-2013)“…Designer synthetic cannabinoids like JWH-018 and AM2201 have unique clinical toxicity. Cytochrome-P450-mediated metabolism of each leads to the generation of…”
Get full text
Journal Article -
13
LC-MS/MS confirmation of 11-nor-9-carboxy-tetrahydrocannabinol (Δ8, Δ9, Δ1°) and hexahydrocannabinol (HHC) metabolites in authentic urine specimens
Published in Journal of analytical toxicology (26-11-2024)“…Recently, tetrahydrocannabinol (THC) isomers and other semi-synthetic cannabinoids have been introduced into the consumer market as alternatives to botanical…”
Get full text
Journal Article -
14
The Spice of Death: Sudden Cardiac Arrest After Novel Psychoactive Substance Exposure
Published in Pediatric emergency care (15-09-2021)Get full text
Journal Article -
15
The Role of Norbuprenorphine in Buprenorphine‐Induced Neonatal Abstinence Syndrome: A Pilot Study
Published in The FASEB journal (01-04-2017)“…Abstract only Opioid abuse during pregnancy may cause drug dependence in the fetus, and the abrupt discontinuation of opioid exposure at birth may induce…”
Get full text
Journal Article -
16
Atypical Pharmacodynamic Properties and Metabolic Profile of the Abused Synthetic Cannabinoid AB-PINACA: Potential Contribution to Pronounced Adverse Effects Relative to Δ 9 -THC
Published in Frontiers in pharmacology (2018)“…Recreational use of marijuana is associated with few adverse effects, but abuse of synthetic cannabinoids (SCBs) can result in anxiety, psychosis, chest pain,…”
Get full text
Journal Article -
17
K2 Toxicity: Fatal case of psychiatric complications following AM-2201 exposure
Published in Journal of forensic sciences (03-07-2013)Get full text
Journal Article -
18
K2 Toxicity: Fatal Case of Psychiatric Complications Following AM2201 Exposure
Published in Journal of Forensic Sciences (01-11-2013)Get full text
Report