Search Results - "Patterson, Laurel M"

Orexin Signaling in the Ventral Tegmental Area Is Required for High-Fat Appetite Induced by Opioid Stimulation of the Nucleus Accumbens by Zheng, Huiyuan, Patterson, Laurel M, Berthoud, Hans-Rudolf

“…The overriding of satiety and homeostatic control mechanisms by cognitive, rewarding, and emotional aspects of palatable foods may contribute to the evolving…”
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"Liking" and "wanting" of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition by Shin, Andrew C, Townsend, R Leigh, Patterson, Laurel M, Berthoud, Hans-Rudolf

“…Cross-sectional studies in both humans and animals have demonstrated associations between obesity and altered reward functions at the behavioral and neural…”
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Meal patterns, satiety, and food choice in a rat model of Roux-en-Y gastric bypass surgery by Zheng, Huiyuan, Shin, Andrew C, Lenard, Natalie R, Townsend, R Leigh, Patterson, Laurel M, Sigalet, David L, Berthoud, Hans-Rudolf

“…Gastric bypass surgery efficiently and lastingly reduces excess body weight and reverses type 2 diabetes in obese patients. Although increased energy…”
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Orexin-A projections to the caudal medulla and orexin-induced c-Fos expression, food intake, and autonomic function by Zheng, Huiyuan, Patterson, Laurel M., Berthoud, Hans-Rudolf

“…Orexin‐expressing neurons in the hypothalamus project throughout the neuraxis and are involved in regulation of the sleep/wake cycle, food intake, and…”
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High-fat intake induced by mu-opioid activation of the nucleus accumbens is inhibited by Y1R-blockade and MC3/4R- stimulation by Zheng, Huiyuan, Townsend, R. Leigh, Shin, Andrew C, Patterson, Laurel M, Phifer, Curtis B, Berthoud, Hans-Rudolf

“…Abstract Nucleus accumbens mu-opioid receptor activation can strongly stimulate intake of high-fat food in satiated rats, and one of the mechanisms involves…”
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Extracellular Signal-Regulated Kinase 1/2 Signaling Pathway in Solitary Nucleus Mediates Cholecystokinin-Induced Suppression of Food Intake in Rats by Sutton, Gregory M, Patterson, Laurel M, Berthoud, Hans-Rudolf

“…Increased food intake is a major factor in the development of obesity, and the control of meal size is a valid approach to reduce food intake in humans. Meal…”
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Vanilloid receptor (VR1) expression in vagal afferent neurons innervating the gastrointestinal tract by Patterson, Laurel M, Zheng, Huiyuan, Ward, Sean M, Berthoud, Hans-Rudolf

“…The vanilloid receptor VR1 is a nonselective cation channel activated by capsaicin as well as increases in temperature and acidity, and can be viewed as…”
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GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents by Ye, Jianping, Hao, Zheng, Mumphrey, Michael B, Townsend, R Leigh, Patterson, Laurel M, Stylopoulos, Nicholas, Münzberg, Heike, Morrison, Christopher D, Drucker, Daniel J, Berthoud, Hans-Rudolf

“…Exaggerated GLP-1 and PYY secretion is thought to be a major mechanism in the reduced food intake and body weight after Roux-en-Y gastric bypass surgery. Here,…”
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Vagal Innervation of Intestine Contributes to Weight Loss After Roux-en-Y Gastric Bypass Surgery in Rats by Hao, Zheng, Townsend, R. Leigh, Mumphrey, Michael B., Patterson, Laurel M., Ye, Jianping, Berthoud, Hans-Rudolf

“…Background It is conceivable that overstimulation of chemo- and mechano-sensors in the Roux and common limbs by uncontrolled influx of undigested nutrients…”
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Sleeve Gastrectomy Does Not Cause Hypertrophy and Reprogramming of Intestinal Glucose Metabolism in Rats by Mumphrey, Michael B., Hao, Zheng, Townsend, R. Leigh, Patterson, Laurel M., Berthoud, Hans-Rudolf

“…Background Clinical studies have shown similar rapid improvements in body mass and glycemic control after Roux-en-Y gastric bypass (RYGB) and vertical sleeve…”
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Immunohistochemical identification of cholecystokinin A receptors on interstitial cells of Cajal, smooth muscle, and enteric neurons in rat pylorus by Patterson, Laurel M, Zheng, Huiyuan, Ward, Sean M, Berthoud, Hans-Rudolf

“…One of the physiological functions of circulating cholecystokinin (CCK) is in the control of the pyloric sphincter and the subsequent delivery of nutrients to…”
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Distribution and structure of vagal afferent intraganglionic laminar endings (IGLEs) in the rat gastrointestinal tract by Berthoud, H R, Patterson, L M, Neumann, F, Neuhuber, W L

“…Intraganglionic laminar endings (IGLEs) are special terminal structures of vagal afferent fibers and have been demonstrated in the myenteric plexus of…”
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Longitudinal Assessment of Food Intake, Fecal Energy Loss, and Energy Expenditure After Roux-en-Y Gastric Bypass Surgery in High-Fat-Fed Obese Rats by Shin, Andrew C., Zheng, Huiyuan, Townsend, R. Leigh, Patterson, Laurel M., Holmes, Gregory M., Berthoud, Hans-Rudolf

“…Background The efficacy of Roux-en-Y gastric bypass (RYGB) surgery to produce weight loss has been well-documented, but few studies have measured the key…”
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Brain stem melanocortinergic modulation of meal size and identification of hypothalamic POMC projections by Zheng, Huiyuan, Patterson, Laurel M, Phifer, Curtis B, Berthoud, Hans-Rudolf

“…Metabolic, cognitive, and environmental factors processed in the forebrain modulate food intake by changing the potency of direct controls of meal ingestion in…”
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Brainstem mechanisms integrating gut-derived satiety signals and descending forebrain information in the control of meal size by Berthoud, Hans-Rudolf, Sutton, Gregory M., Townsend, R. Leigh, Patterson, Laurel M., Zheng, Huiyuan

“…Ingestive behavior is controlled by a complex interplay between signals conveying availability of (1) potentially ingestible food in the environment, (2)…”
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Capsaicin-resistant vagal afferent fibers in the rat gastrointestinal tract: anatomical identification and functional integrity by Berthoud, Hans-Rudolf, Patterson, Laurel M, Willing, Alison E, Mueller, Karin, Neuhuber, Winfried L

“…The presence and distribution of vagal fibers and terminals throughout esophagus and gastrointestinal tract that could be anterogradely labeled by nodose…”
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Melanocortinergic Modulation of Cholecystokinin-Induced Suppression of Feeding through Extracellular Signal-Regulated Kinase Signaling in Rat Solitary Nucleus by Sutton, Gregory M, Duos, Bronwyn, Patterson, Laurel M, Berthoud, Hans-Rudolf

“…Signals from the gut and hypothalamus converge in the caudal brainstem to control ingestive behavior. We have previously shown that phosphorylation of ERK1/2…”
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A potential role for hypothalamomedullary POMC projections in leptin-induced suppression of food intake by Zheng, Huiyuan, Patterson, Laurel M, Rhodes, Christopher J, Louis, Gwendolyn W, Skibicka, Karolina P, Grill, Harvey J, Myers, Jr, Martin G, Berthoud, Hans-Rudolf

“…Melanocortin-3/4 receptor ligands administered to the caudal brain stem potently modulate food intake by changing meal size. The origin of the endogenous…”
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Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade by Mumphrey, Michael B., Hao, Zheng, Townsend, R. Leigh, Patterson, Laurel M, Morrison, Christopher D., Münzberg, Heike, Stylopoulos, Nicholas, Ye, Jianping, Berthoud, Hans‐Rudolf

“…Objective To test the commonly held assumption that gastric bypass surgery lowers body weight because it limits the ability to eat large amounts of food…”
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Phenotype of neurons in the nucleus of the solitary tract that express CCK-induced activation of the ERK signaling pathway by Babic, Tanja, Townsend, R Leigh, Patterson, Laurel M, Sutton, Gregory M, Zheng, Huiyuan, Berthoud, Hans-Rudolf

“…The satiating potency of CCK has been well characterized, including its mediation by capsaicin-sensitive vagal primary afferents. We have previously shown that…”
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