Search Results - "Patterson, Larry T."
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Atlas of Gene Expression in the Developing Kidney at Microanatomic Resolution
Published in Developmental cell (01-11-2008)“…Kidney development is based on differential cell-type-specific expression of a vast number of genes. While multiple critical genes and pathways have been…”
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Gene expression in early ischemic renal injury: clues towards pathogenesis, biomarker discovery, and novel therapeutics
Published in Molecular Genetics and Metabolism (01-12-2003)“…Acute renal failure (ARF) represents a common and serious problem in clinical medicine. Renal ischemia–reperfusion injury (IRI) is the major cause of ARF in…”
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The Preserving Kidney Function in Children With CKD (PRESERVE) Study: Rationale, Design, and Methods
Published in Kidney medicine (01-11-2023)“…PRESERVE seeks to provide new knowledge to inform shared decision-making regarding blood pressure (BP) management for pediatric chronic kidney disease (CKD)…”
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Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development
Published in BMC biology (10-04-2007)“…The pygopus gene of Drosophila encodes an essential component of the Armadillo (beta-catenin) transcription factor complex of canonical Wnt signaling. To…”
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pygopus 2 has a crucial, Wnt pathway-independent function in lens induction
Published in Development (Cambridge) (15-05-2007)“…Drosophila Pygopus was originally identified as a core component of the canonical Wnt signaling pathway and a transcriptional coactivator. Here we have…”
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Cessation of renal morphogenesis in mice
Published in Developmental biology (15-10-2007)“…The kidney develops by cycles of ureteric bud branching and nephron formation. The cycles begin and are sustained by reciprocal inductive interactions and…”
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Atlas of Hox gene expression in the developing kidney
Published in Developmental dynamics (01-04-2004)“…Hox genes often play important roles in segment identity determination and organogenesis. To better understand the roles of Hox genes during kidney…”
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Microdissection of the gene expression codes driving nephrogenesis
Published in Organogenesis (01-10-2010)“…The kidney represents an excellent model system for learning the principles of organogenesis. It is intermediate in complexity, and employs many commonly used…”
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Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities
Published in Nature (London) (04-03-1993)“…The Pax genes comprise a family of transcription factors active in specific tissues during embryonic development and are associated with at least three…”
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Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients
Published in Pediatric nephrology (Berlin, West) (01-02-2019)“…Background Hemodialysis (HD) guidelines recommend permanent vascular access (PVA) in children unlikely to receive kidney transplant within 1 year of starting…”
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Microarray analysis of focal segmental glomerulosclerosis
Published in American journal of nephrology (01-07-2004)“…Focal segmental glomerulosclerosis (FSGS) is a leading cause of chronic renal failure in children. Recent studies have begun to define the molecular…”
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Correction to: Predictors of patency for arteriovenous fistulae and grafts in pediatric hemodialysis patients
Published in Pediatric nephrology (Berlin, West) (01-08-2019)“…The original version of this article unfortunately contained a mistake. The name of Vimal Chadha was presented incorrectly. The corrected author list is given…”
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Microarrays and RNA-Seq identify molecular mechanisms driving the end of nephron production
Published in BMC developmental biology (12-03-2011)“…The production of nephrons suddenly ends in mice shortly after birth when the remaining cells of the multi-potent progenitor mesenchyme begin to differentiate…”
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Defining the genetic blueprint of kidney development
Published in Pediatric nephrology (Berlin, West) (01-09-2011)“…Thousands of genes show differential expression patterns during kidney development, suggesting that the genetic program driving this process is complex. While…”
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A catalogue of gene expression in the developing kidney
Published in Kidney international (01-11-2003)“…A catalogue of gene expression in the developing kidney. Although many genes with important function in kidney morphogenesis have been described, it is clear…”
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Hoxa11 and Hoxd11 regulate branching morphogenesis of the ureteric bud in the developing kidney
Published in Development (Cambridge) (01-06-2001)“…Hoxa11 and Hoxd11 are functionally redundant during kidney development. Mice with homozygous null mutation of either gene have normal kidneys, but double…”
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Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney development
Published in Developmental biology (15-05-2006)“…The Hox11 paralogous genes play critical roles in kidney development. They are expressed in the early metanephric mesenchyme and are required for the induction…”
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Induction of renal tubular cell apoptosis in focal segmental glomerulosclerosis : Roles of proteinuria and fas-dependent pathways
Published in Journal of the American Society of Nephrology (01-02-2005)“…The hypothesis that apoptosis represents a proximate mechanism by which tubule cells are damaged in FSGS was tested. Thirty kidney biopsy specimens from…”
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Laser capture-microarray analysis of Lim1 mutant kidney development
Published in Genesis (New York, N.Y. : 2000) (01-07-2007)“…The Lim1 gene has essential functions during several stages of kidney development. In particular, a tissue‐specific knockout in the early metanephric…”
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Differential expression and function of cadherin-6 during renal epithelium development
Published in Development (Cambridge) (01-03-1998)“…The cadherin gene family encodes calcium-dependent adhesion molecules that promote homophilic interactions among cells. During embryogenesis, differential…”
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