Search Results - "Patterson, Amy P"
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Human SR-BI and SR-BII Potentiate Lipopolysaccharide-Induced Inflammation and Acute Liver and Kidney Injury in Mice
Published in The Journal of immunology (1950) (01-04-2016)“…The class B scavenger receptors BI (SR-BI) and BII (SR-BII) are high-density lipoprotein receptors that recognize various pathogens, including bacteria and…”
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Scavenger receptor-BI is a receptor for lipoprotein(a)
Published in Journal of lipid research (01-09-2013)“…Scavenger receptor class B type I (SR-BI) is a multi-ligand receptor that binds a variety of lipoproteins, including high density lipoprotein (HDL) and low…”
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Role of Human CD36 in Bacterial Recognition, Phagocytosis, and Pathogen-Induced JNK-Mediated Signaling
Published in The Journal of immunology (1950) (15-11-2008)“…Scavenger receptor CD36 mediates Staphylococcus aureus phagocytosis and initiates TLR2/6 signaling. We analyzed the role of CD36 in the uptake and…”
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SR-BI mediates neutral lipid sorting from LDL to lipid droplets and facilitates their formation
Published in PloS one (15-10-2020)“…SR-BI binds various lipoproteins, including HDL, LDL as well as VLDL, and mediates selective cholesteryl ester (CE) uptake. HDL derived CE accumulates in…”
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CD36 Is a Novel Serum Amyloid A (SAA) Receptor Mediating SAA Binding and SAA-induced Signaling in Human and Rodent Cells
Published in The Journal of biological chemistry (12-03-2010)“…Serum amyloid A (SAA) is a major acute phase protein involved in multiple physiological and pathological processes. This study provides experimental evidence…”
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Human SR-BII mediates SAA uptake and contributes to SAA pro-inflammatory signaling in vitro and in vivo
Published in PloS one (19-04-2017)“…Serum amyloid A (SAA) is an acute phase protein with cytokine-like and chemotactic properties, that is markedly up-regulated during various inflammatory…”
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Endothelial Expression of Scavenger Receptor Class B, Type I Protects against Development of Atherosclerosis in Mice
Published in BioMed research international (01-01-2015)“…The role of scavenger receptor class B, type I (SR-BI) in endothelial cells (EC) was examined in several novel transgenic mouse models expressing SR-BI in…”
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Serum Amyloid A Binding to CLA-1 (CD36 and LIMPII Analogous-1) Mediates Serum Amyloid A Protein-induced Activation of ERK1/2 and p38 Mitogen-activated Protein Kinases
Published in The Journal of biological chemistry (04-03-2005)“…Serum amyloid A protein (SAA) is an acute-phase reactant, known to mediate pro-inflammatory cellular responses. This study reports that CLA-1 (CD36 and LIMPII…”
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Research as a Part of Public Health Emergency Response
Published in The New England journal of medicine (28-03-2013)“…The authors review lessons learned from several recent public health emergencies and argue that we must conduct research during emergencies to improve our…”
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Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway
Published in Journal of lipid research (01-04-2003)“…In order to examine the necessary structural features for a protein to promote lipid efflux by the ABCA1 transporter, synthetic peptides were tested on…”
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National Heart, Lung, and Blood Institute (NHLBI) Strategic Visioning
Published in Journal of the American College of Cardiology (24-03-2015)“…Landmark clinical trials established penicillin, blood transfusions, and hydroxyurea as mainstay therapeutic options for the management of sickle cell disease…”
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Binding and Internalization of Lipopolysaccharide by Cla-1, a Human Orthologue of Rodent Scavenger Receptor B1
Published in The Journal of biological chemistry (20-06-2003)“…Scavenger receptor, class B, type I (SR-BI) mediates selective uptake of high density lipoprotein (HDL) cholesteryl ester. SR-BI recognizes HDL, low density…”
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Colon Epithelial MicroRNA Network in Fatty Liver
Published in Canadian journal of gastroenterology & hepatology (01-01-2018)“…Background & Aims. Intestinal barrier alterations are associated with fatty liver (FL) and metabolic syndrome (MetS), but microRNA (miR) signaling pathways in…”
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Lipopolysaccharide Down Regulates Both Scavenger Receptor B1 and ATP Binding Cassette Transporter A1 in RAW Cells
Published in Infection and Immunity (01-06-2002)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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CLA-1 and Its Splicing Variant CLA-2 Mediate Bacterial Adhesion and Cytosolic Bacterial Invasion in Mammalian Cells
Published in Proceedings of the National Academy of Sciences - PNAS (07-11-2006)“…CD36 and LIMPII analog 1, CLA-1, and its splicing variant, CLA-2 (SR-BI and SR-BII in rodents), are human high density lipoprotein receptors with an identical…”
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APOBEC3-induced mutation of the hepatitis virus B DNA genome occurs during its viral RNA reverse transcription into (−)-DNA
Published in The Journal of biological chemistry (01-08-2021)“…APOBEC3s are innate single-stranded DNA cytidine-to-uridine deaminases that catalyze mutations in both pathogen and human genomes with significant roles in…”
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Heat shock proteins stimulate APOBEC-3–mediated cytidine deamination in the hepatitis B virus
Published in The Journal of biological chemistry (11-08-2017)“…Apolipoprotein B mRNA-editing enzyme catalytic subunit 3 (APOBEC-3) enzymes are cytidine deaminases that are broadly and constitutively expressed. They are…”
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Class B Scavenger Receptors BI and BII Protect against LPS-Induced Acute Lung Injury in Mice by Mediating LPS
Published in Infection and immunity (16-09-2021)“…Recent studies suggest an anti-inflammatory protective role for class B scavenger receptor BI (SR-BI) in endotoxin-induced inflammation and sepsis. Other data,…”
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Antagonism of scavenger receptor CD36 by 5A peptide prevents chronic kidney disease progression in mice independent of blood pressure regulation
Published in Kidney international (01-04-2016)“…Scavenger receptor CD36 participates in lipid metabolism and inflammatory pathways important for cardiovascular disease and chronic kidney disease (CKD). Few…”
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