Search Results - "Patten, Monica"

Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy by Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie

“…Hypertrophic cardiomyopathy (HCM) is a cardiac genetic disease accompanied by structural and contractile alterations. We identified a rare c.740C>T (p.T247M)…”
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Impact of Myocardial Fibrosis on Left Ventricular Function Evaluated by Feature-Tracking Myocardial Strain Cardiac Magnetic Resonance in Competitive Male Triathletes With Normal Ejection Fraction by Tahir, Enver, Starekova, Jitka, Muellerleile, Kai, Freiwald, Eric, Stritzky, Alexandra von, Münch, Julia, Avanesov, Maxim, Weinrich, Julius Matthias, Stehning, Christian, Cavus, Ersin, Bohnen, Sebastian, Radunski, Ulf K., Blankenberg, Stefan, Adam, Gerhard, Simon, Perikles, Pressler, Axel, Patten, Monica, Lund, Gunnar K.

“…Background:To analyze the effect of myocardial fibrosis on left ventricular (LV) function evaluated by feature-tracking strain analysis by cine cardiac…”
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Comparison of classical Fabry and its p.D313Y and p.A143T variants by cardiac T1 mapping, LGE and feature tracking myocardial strain by Avanesov, Maxim, Asgari, Anahid, Muschol, Nicole, Köhn, Anja Friederike, Tahir, Enver, Adam, Gerhard, Kirchhof, Paulus, Lund, Gunnar, Cavus, Ersin, Patten, Monica

“…Cardiac manifestation of classical Fabry disease (cFD) varies with sex and presence of left ventricular hypertrophy. p.D313Y/p.A143T variants (vFD) represent…”
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A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy by Thottakara, Tilo, Lund, Natalie, Krämer, Elisabeth, Kirchhof, Paulus, Carrier, Lucie, Patten, Monica

“…(1) Background: Left ventricular hypertrophy, myocardial disarray and interstitial fibrosis are the hallmarks of hypertrophic cardiomyopathy (HCM). Access to…”
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Ablation of Atrial Fibrillation in Patients With Hypertrophic Cardiomyopathy: Treatment Strategy, Characteristics of Consecutive Atrial Tachycardia and Long-Term Outcome by Dinshaw, Leon, Münkler, Paula, Schäffer, Benjamin, Klatt, Niklas, Jungen, Christiane, Dickow, Jannis, Tamenang, Annika, Schleberger, Ruben, Pecha, Simon, Pinnschmidt, Hans, Patten, Monica, Reichenspurner, Hermann, Willems, Stephan, Meyer, Christian

“…Background Atrial fibrillation (AF) is common in patients with hypertrophic cardiomyopathy (HCM) and is associated with a deterioration of clinical status…”
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Evaluation of MYBPC3 trans-Splicing and Gene Replacement as Therapeutic Options in Human iPSC-Derived Cardiomyocytes by Prondzynski, Maksymilian, Krämer, Elisabeth, Laufer, Sandra D., Shibamiya, Aya, Pless, Ole, Flenner, Frederik, Müller, Oliver J., Münch, Julia, Redwood, Charles, Hansen, Arne, Patten, Monica, Eschenhagen, Thomas, Mearini, Giulia, Carrier, Lucie

“…Gene therapy is a promising option for severe forms of genetic diseases. We previously provided evidence for the feasibility of trans-splicing, exon skipping,…”
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Hereditary transthyretin-related amyloidosis is frequent in polyneuropathy and cardiomyopathy of no obvious aetiology by Skrahina, Volha, Grittner, Ulrike, Beetz, Christian, Skripuletz, Thomas, Juenemann, Martin, Krämer, Heidrun H., Hahn, Katrin, Rieth, Andreas, Schaechinger, Volker, Patten, Monica, Tanislav, Christian, Achenbach, Stephan, Assmus, Birgit, Knebel, Fabian, Gingele, Stefan, Skrahin, Aliaksandr, Hartkamp, Jörg, Förster, Toni M., Roesner, Sabine, Pereira, Catarina, Rolfs, Arndt

“…Hereditary Transthyretin-Related Amyloidosis, a clinically heterogeneous autosomal dominant disease caused by pathogenic variants in the TTR gene, is…”
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Association of NT-proBNP and hs-cTnT with Imaging Markers of Diastolic Dysfunction and Focal Myocardial Fibrosis in Hypertrophic Cardiomyopathy by Chevalier, Céleste, Wendner, Miriam, Suling, Anna, Cavus, Ersin, Muellerleile, Kai, Lund, Gunnar, Kirchhof, Paulus, Patten, Monica

“…Serum biomarkers such as N-terminal prohormone of the brain natriuretic peptide (NT-proBNP) and cardiac troponins are elevated in patients with hypertrophic…”
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Serum Matrix Metalloproteinases as Quantitative Biomarkers for Myocardial Fibrosis and Sudden Cardiac Death Risk Stratification in Patients With Hypertrophic Cardiomyopathy by Münch, Julia, MD, Avanesov, Maxim, MD, Bannas, Peter, MD, Säring, Dennis, PhD, Krämer, Elisabeth, Mearini, Giulia, PhD, Carrier, Lucie, PhD, Suling, Anna, PhD, Lund, Gunnar, MD, Patten, Monica, MD

“…Abstract Background Hypertrophic cardiomyopathy (HCM) is associated with an increased risk of sudden cardiac death due to ventricular tachycardia (VT), and…”
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Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy by Prondzynski, Maksymilian, Lemoine, Marc D, Zech, Antonia TL, Horváth, András, Di Mauro, Vittoria, Koivumäki, Jussi T, Kresin, Nico, Busch, Josefine, Krause, Tobias, Krämer, Elisabeth, Schlossarek, Saskia, Spohn, Michael, Friedrich, Felix W, Münch, Julia, Laufer, Sandra D, Redwood, Charles, Volk, Alexander E, Hansen, Arne, Mearini, Giulia, Catalucci, Daniele, Meyer, Christian, Christ, Torsten, Patten, Monica, Eschenhagen, Thomas, Carrier, Lucie

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Analysis of Contractile Function of Permeabilized Human Hypertrophic Cardiomyopathy Multicellular Heart Tissue by Kresin, Nico, Stücker, Sabrina, Krämer, Elisabeth, Flenner, Frederik, Mearini, Giulia, Münch, Julia, Patten, Monica, Redwood, Charles, Carrier, Lucie, Friedrich, Felix W

“…Background: Many forms of hypertrophic cardiomyopathy (HCM) show an increased myofilament Ca2+ sensitivity. This observation has been mainly made in HCM mouse…”
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Orthostatic blood pressure test for risk stratification in patients with hypertrophic cardiomyopathy by Münch, Julia, Aydin, Ali, Suling, Anna, Voigt, Christian, Blankenberg, Stefan, Patten, Monica

“…Hypertrophic cardiomyopathy (HCM) is the most common cause of sudden cardiac death (SCD) in young adults, mainly ascribed to ventricular tachycardia (VT)…”
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Serum Biomarkers of Endothelial Dysfunction in Fabry Associated Cardiomyopathy by Loso, Jefferson, Lund, Natalie, Avanesov, Maxim, Muschol, Nicole, Lezius, Susanne, Cordts, Kathrin, Schwedhelm, Edzard, Patten, Monica

“…Fabry disease (FD) is characterized by early development of vasculopathy and endothelial dysfunction. However, it is unclear whether these findings also play a…”
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Event-Recorder Monitoring in the Diagnosis of Atrial Fibrillation in Symptomatic Patients: Subanalysis of the SOPAT Trial by PATTEN, MONICA, MAAS, RENKE, KARIM, AMINA, MÜLLER, HANS-WALTER, SIMONOVSKY, ROSA, MEINERTZ, THOMAS

“…In the SOPAT (suppression of paroxysmal atrial tachyarrhythmias) trial, a high number of asymptomatic atrial fibrillation (AF) episodes were registered in…”
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Translational investigation of electrophysiology in hypertrophic cardiomyopathy by Flenner, Frederik, Jungen, Christiane, Küpker, Nadine, Ibel, Antonia, Kruse, Martin, Koivumäki, Jussi T., Rinas, Anna, Zech, Antonia T.L., Rhoden, Alexandra, Wijnker, Paul J.M., Lemoine, Marc D., Steenpass, Anna, Girdauskas, Evaldas, Eschenhagen, Thomas, Meyer, Christian, van der Velden, Jolanda, Patten-Hamel, Monica, Christ, Torsten, Carrier, Lucie

“…Hypertrophic cardiomyopathy (HCM) patients are at increased risk of ventricular arrhythmias and sudden cardiac death, which can occur even in the absence of…”
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Association of Asymmetric Dimethylarginine and Diastolic Dysfunction in Patients with Hypertrophic Cardiomyopathy by Cordts, Kathrin, Seelig, Doreen, Lund, Natalie, Carrier, Lucie, Böger, Rainer H, Avanesov, Maxim, Tahir, Enver, Schwedhelm, Edzard, Patten, Monica

“…Despite genetic heterogeneity, early manifestation of diastolic dysfunction (DD) is common in hypertrophic cardiomyopathy (HCM). Nitric oxide (NO) may…”
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Generation of bi-allelic MYBPC3 truncating mutant and isogenic control from an iPSC line of a patient with hypertrophic cardiomyopathy by Warnecke, Nele, Ulmer, Bärbel M., Laufer, Sandra D., Shibamiya, Aya, Krämer, Elisabeth, Neuber, Christiane, Hanke, Sophia, Behrens, Charlotta, Loos, Malte, Münch, Julia, Kühnisch, Jirko, Klaassen, Sabine, Eschenhagen, Thomas, Patten-Hamel, Monica, Carrier, Lucie, Mearini, Giulia

“…MYBPC3 is the most frequently affected gene in hypertrophic cardiomyopathy (HCM), which is an autosomal-dominant cardiac disease caused by mutations in…”
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Taking the heavy load off arrhythmogenic right ventricular cardiomyopathy by Fabritz, Larissa, Patten, Monica, Kirchhof, Paulus

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Circumstances of Suicide Among Lesbian, Gay, Bisexual and Transgender Individuals by Patten, Monica, Carmichael, Heather, Moore, Alison, Velopulos, Catherine

“…•We examined suicide victims who were lesbian, gay, bisexual or transgender (LGBT).•LGBT victims of suicide were younger than their heterosexual or cisgender…”
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Myocardial Fibrosis in Competitive Triathletes Detected by Contrast-Enhanced CMR Correlates With Exercise-Induced Hypertension and Competition History by Tahir, Enver, Starekova, Jitka, Muellerleile, Kai, von Stritzky, Alexandra, Münch, Julia, Avanesov, Maxim, Weinrich, Julius M., Stehning, Christian, Bohnen, Sebastian, Radunski, Ulf K., Freiwald, Eric, Blankenberg, Stefan, Adam, Gerhard, Pressler, Axel, Patten, Monica, Lund, Gunnar K.

“…This study analyzed the presence of myocardial fibrosis detected by late gadolinium-enhancement (LGE) cardiac magnetic resonance (CMR) in correlation with the…”
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