Search Results - "Patten, Kelley T."
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The Effects of Chronic Exposure to Ambient Traffic-Related Air Pollution on Alzheimer's Disease Phenotypes in Wildtype and Genetically Predisposed Male and Female Rats
Published in Environmental health perspectives (01-05-2021)“…Epidemiological data link traffic-related air pollution (TRAP) to increased risk of Alzheimer's disease (AD). Preclinical data corroborating this association…”
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Pathological Cardiopulmonary Evaluation of Rats Chronically Exposed to Traffic-Related Air Pollution
Published in Environmental health perspectives (01-12-2020)“…Traffic-related air pollution (TRAP) is made up of complex mixtures of particulate matter, gases and volatile compounds. However, the effects of TRAP on the…”
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Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats
Published in Translational psychiatry (27-05-2020)“…Epidemiological studies link traffic-related air pollution (TRAP) to increased risk for various neurodevelopmental disorders (NDDs); however, there are limited…”
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Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner
Published in Frontiers in cellular neuroscience (22-04-2022)“…Epidemiological studies have demonstrated that air pollution is a significant risk factor for age-related dementia, including Alzheimer's disease (AD). It has…”
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Developmental exposure to near roadway pollution produces behavioral phenotypes relevant to neurodevelopmental disorders in juvenile rats
Published in Translational psychiatry (17-08-2020)“…Epidemiological studies consistently implicate traffic-related air pollution (TRAP) and/or proximity to heavily trafficked roads as risk factors for…”
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Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer’s disease
Published in Toxicology reports (01-01-2022)“…Traffic-related air pollution (TRAP) is linked to increased risk for age-related dementia, including Alzheimer’s disease (AD). The gut microbiome is posited to…”
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Probing changes in brain esterified oxylipin concentrations during the early stages of pathogenesis in Alzheimer’s Disease transgenic rats
Published in Neuroscience letters (20-11-2022)“…•Brain esterified oxylipins were measured in transgenic Alzheimer’s Disease (AD) rats.•Measurements were performed at 10 months of age when pathology is not…”
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Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats
Published in Environmental toxicology and pharmacology (01-07-2022)“…Chronic exposure to traffic-related air pollution (TRAP) is known to promote systemic inflammation, which is thought to underlie respiratory, cardiovascular,…”
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Gene-environment interactions determine risk for dementia: the influence of lifestyle on genetic risk for dementia
Published in Annals of translational medicine (01-12-2019)Get full text
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Cell-extrinsic consequences of epithelial stress: activation of protumorigenic tissue phenotypes
Published in Breast cancer research : BCR (07-12-2012)“…Tumors are characterized by alterations in the epithelial and stromal compartments, which both contribute to tumor promotion. However, where, when, and how the…”
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