Search Results - "Patten, D A"

Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism by Thrush, A B, Antoun, G, Nikpay, M, Patten, D A, DeVlugt, C, Mauger, J-F, Beauchamp, B L, Lau, P, Reshke, R, Doucet, É, Imbeault, P, Boushel, R, Gibbings, D, Hager, J, Valsesia, A, Slack, R S, Al-Dirbashi, O Y, Dent, R, McPherson, R, Harper, M-E

“…Background/Objectives: Inter-individual variability in weight loss during obesity treatment is complex and poorly understood. Here we use whole body and tissue…”
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Lactobacillus-produced exopolysaccharides and their potential health benefits: a review by Patten, D A, Laws, A P

“…Lactic acid bacteria, such as those of the Lactobacillus genus, naturally reside within the microbiota of the human body and have long been used as starter…”
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IL-15 improves skeletal muscle oxidative metabolism and glucose uptake in association with increased respiratory chain supercomplex formation and AMPK pathway activation by Nadeau, L., Patten, D.A., Caron, A., Garneau, L., Pinault-Masson, E., Foretz, M., Haddad, P., Anderson, B.G., Quinn, L.S., Jardine, K., McBurney, M.W., Pistilli, E.E., Harper, M.E., Aguer, C.

“…IL-15 is believed to play a role in the beneficial impact of exercise on muscle energy metabolism. However, previous studies have generally used…”
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Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3 by McBride, S., Wei-LaPierre, L., McMurray, F., MacFarlane, M., Qiu, X., Patten, D.A., Dirksen, R.T., Harper, M.-E.

“…Mitochondrial reactive oxygen species (ROS) are important cellular signaling molecules, but can cause oxidative damage if not kept within tolerable limits. An…”
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LKB1-regulated adaptive mechanisms are essential for neuronal survival following mitochondrial dysfunction by Germain, Marc, Nguyen, Angela P, Khacho, Mireille, Patten, David A, Screaton, Robert A, Park, David S, Slack, Ruth S

“…Mitochondrial dysfunction plays an important role in the etiology of neurodegenerative diseases. However, the progressive nature of neuronal loss in genetic…”
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(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]-bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro by KIRSHENBAUM, M. R, CHEN, S.-F, SIPPLE, P, PATTEN, A. D, DEXTER, D, SEITZ, S. P, GROSS, J. L, BEHRENS, C. H, PAPP, L. M, STAFFORD, M. M, SUN, J.-H, BEHRENS, D. L, FREDERICKS, J. R, POLKUS, S. T

“…(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), is a…”
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XB596, a promising bis-naphthalimide anti-cancer agent by Chen, S F, Behrens, D L, Behrens, C H, Czerniak, P M, Dexter, D L, Dusak, B L, Fredericks, J R, Gale, K C, Gross, J L, Jiang, J B

“…We have synthesized a promising class of bis-naphthalimide anti-tumor agents. A representative compound in this series, XB596, exhibits potent in vitro growth…”
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The synthesis and antitumor evaluation of unsymmetrical bis-imides by Cherney, Robert J., Swartz, Stephen G., Patten, Arthur D., Akamike, Emeka, Sun, Jung-Hui, Kaltenbach, Robert F., Seitz, Steven P., Behrens, Carl H., Getahun, Zelleka, Trainor, George L., Vavala, Mike, Kirshenbaum, Mindy R., Papp, Lisa M., Stafford, Margaret P., Czerniak, Philip M., Diamond, Richard J., McRipley, Ronald J., Page, Roni J., Gross, Janet L.

“…Unsymmetrical bis-imides 1 were synthesized and evaluated as potential antitumor agents. These novel bis-imides were assessed using three criteria: in vitro…”
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Photoisomerization of 4-hydroxypyrylium cations in concentrated sulfuric acid by Pavlik, James W, Patten, Arthur D, Bolin, David R, Bradford, Kenneth C, Clennan, Edward L

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Case of the day. Angioblastic meningioma by Auringer, S T, Patten, D A, Sumner, T E

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A concise total synthesis of defucogilvocarcin V by application of the Meyers biaryl strategy: ortho- and para-selective functionalizations of the A ring by Patten, Arthur D, Nguyen Nhan Huy, Danishefsky, Samuel J

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Synthesis of two useful, enenatiomerically pure derivatives of (S)-4-hydroxy-2-cyclohexenone by AUDIA, J. E, BOISVERT, L, PATTEN, A. D, VILLALOBOS, A, DANISHEFSKY, S. J

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