Search Results - "Pattanayak, Manas R."
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Strain‐Promoted 1,3‐Dithiolium‐4‐olates–Alkyne Cycloaddition
Published in Angewandte Chemie International Edition (07-10-2019)“…Reported here is the reactivity of mesoionic 1,3‐dithiolium‐4‐olates towards strained alkynes, leading to thiophene cycloaddition products. In the process, the…”
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Journal Article -
2
Iodocyclization and Prins-Type Macrocyclization: An Efficient Formal Synthesis of Leucascandrolide A
Published in Organic letters (01-04-2011)“…The formal total synthesis of leucascandrolide A has been achieved in 20 steps from a known epoxide with an overall yield of 11.5% following a recently…”
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Journal Article -
3
Total Synthesis of Myceliothermophins C, D, and E
Published in Angewandte Chemie International Edition (06-10-2014)“…The total synthesis of cytotoxic polyketides myceliothermophins E (1), C (2), and D (3) through a cascade‐based cyclization to form the trans‐fused decalin…”
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Journal Article -
4
Protecting-Group Directed Stereoselective Intramolecular Nozaki-Hiyama-Kishi Reaction: A Concise and Efficient Total Synthesis of Amphidinolactone A
Published in European Journal of Organic Chemistry (01-09-2010)“…A convergent total synthesis of amphidinolactone A, a cytotoxic macrolide from the cultured dinoflagellate Amphidinium sp., is described in 13 linear steps…”
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Book Review Journal Article -
5
Total Synthesis of Thailanstatin A
Published in Journal of the American Chemical Society (22-06-2016)“…The total synthesis of the spliceosome inhibitor thailanstatin A has been achieved in a longest linear sequence of nine steps from readily available starting…”
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6
Streamlined Total Synthesis of Uncialamycin and Its Application to the Synthesis of Designed Analogues for Biological Investigations
Published in Journal of the American Chemical Society (06-07-2016)“…From the enediyne class of antitumor antibiotics, uncialamycin is among the rarest and most potent, yet one of the structurally simpler, making it attractive…”
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Journal Article -
7
Total Synthesis of MyceliothermophinsC, D, and E
Published in Angewandte Chemie International Edition (06-10-2014)“…The total synthesis of cytotoxic polyketides myceliothermophinsE (1), C (2), and D (3) through a cascade-based cyclization to form the trans-fused decalin…”
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Journal Article -
8
Strain‐Promoted 1,3‐Dithiolium‐4‐olates–Alkyne Cycloaddition
Published in Angewandte Chemie (07-10-2019)“…Reported here is the reactivity of mesoionic 1,3‐dithiolium‐4‐olates towards strained alkynes, leading to thiophene cycloaddition products. In the process, the…”
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Journal Article -
9
Ring-closing metathesis (RCM) based synthesis of the macrolactone core of amphidinolactone A
Published in Organic & biomolecular chemistry (21-08-2011)“…A convergent synthesis of the macrolactone core of amphidinolactone A has been achieved, in a 10 step linear sequence with 32% overall yield, through a…”
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Journal Article -
10
Protecting-Group Directed Stereoselective Intramolecular Nozaki-Hiyama-Kishi Reaction: A Concise and Efficient Total Synthesis of Amphidinolactone A (Eur. J. Org. Chem. 25/2010)
Published in European journal of organic chemistry (01-09-2010)“…The cover picture shows shows how a bulky protecting group directs the intramolecular Nozaki–Hiyama–Kishi reaction to afford exclusively one stereoisomer,…”
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Journal Article -
11
Total Synthesis of Myceliothermophins C, D, and E
Published in Angewandte Chemie (06-10-2014)“…The total synthesis of cytotoxic polyketides myceliothermophins E (1), C (2), and D (3) through a cascade‐based cyclization to form the trans‐fused decalin…”
Get full text
Journal Article -
12
Total Synthesis of MyceliothermophinsC, D, and E
Published in Angewandte Chemie (06-10-2014)“…The total synthesis of cytotoxic polyketides myceliothermophinsE (1), C (2), and D (3) through a cascade-based cyclization to form the trans-fused decalin…”
Get full text
Journal Article