Search Results - "Patt, Jörg T"
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1
NMR study on the structure and stability of 4-substituted aromatic iodosyl compounds
Published in Magnetic resonance in chemistry (01-10-2006)“…Two 4‐substituted aromatic iodosyl compounds were investigated with regard to their solubility, stability and chromatographic behaviour. 1‐Iodosyl‐4‐methoxy‐…”
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Journal Article -
2
Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain μ-opioid Receptor Availability in Diet-Induced Obese Male Rats
Published in Frontiers in neuroscience (13-01-2017)“…Brain μ-opioid receptors (MORs) stimulate high-fat (HF) feeding and have been implicated in the distinct long term outcomes on body weight of bariatric surgery…”
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3
Radioiodination of Humic Substances via Azocoupling with 3-[125I]Iodoaniline
Published in Environmental science & technology (01-06-2008)“…A new method is described for radiolabeling humic substances (HS) with iodine radioisotopes. The method radiolabels the electron-rich aromatic moieties of HS…”
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4
A new look at the neuronal nicotinic acetylcholine receptor pharmacophore
Published in European journal of pharmacology (30-03-2000)“…Interest in the field of nicotinic receptors has been recently stimulated both by the discovery of the potential therapeutic effects of new agonists, and by…”
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Journal Article Conference Proceeding -
5
Synthesis and in vivo studies of the stereoisomers of N-[ 11C]methyl-homoepibatidine
Published in Nuclear medicine and biology (01-08-2001)“…The carbon-11 labeled enantiomers of nicotinic acetylcholine receptor (nAChR) ligand N-[ 11C]methyl-homoepibatidine have been synthesized to study the neuronal…”
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Journal Article -
6
Neuronal nAChR stereoselectivity to non-natural epibatidine derivatives
Published in FEBS letters (07-05-1999)“…The frog toxin epibatidine is one of the most powerful ligands of the neuronal nicotinic receptors and derivatives show promising possibilities for labeling in…”
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Journal Article -
7
Synthesis and in vivo studies of [C-11] N-methylepibatidine: comparison of the stereoisomers
Published in Nuclear medicine and biology (01-02-1999)“…The carbon-11-labelled nicotinic acetylcholine receptor (nAChR) agonist N-methylepibatidine was evaluated in vitro and in vivo as a possible positron emission…”
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8
Comparison of in vivo dopamine D2 receptor binding of [ 123I]AIBZM and [ 123I]IBZM in rat brain
Published in Nuclear medicine and biology (01-05-2001)“…[ 123I]AIBZM, (S)-5-[ 123I]-Iodo-N-[(1-ethyl-2-pyrrolidinyl)]methyl-4-amine-2-methoxybenzamide is a derivative with high affinity for the D2 receptor. Labeling…”
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9
On the reaction of 4-substituted trimethyltin aromatics with perchlorylfluoride
Published in Journal of organometallic chemistry (01-09-2006)“…The reactivity of 4-substituted trimethyltin aromatic compounds towards FClO 3 was studied. To evaluate the suitability of [ 18F]perchorylfluoride [ 18F]FClO 3…”
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Journal Article -
10
Chemical modification of epibatidine causes a switch from agonist to antagonist and modifies its selectivity for neuronal nicotinic acetylcholine receptors
Published in Chemistry & biology (01-07-2000)“…Studies of ligand gated channels strongly rely on the availability of compounds that can activate or inhibit with high selectivity one set or a subset of…”
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Journal Article -
11
Synthesis and Electrophysiological Studies of a Novel Epibatidine Analogue
Published in Journal of receptors and signal transduction (1999)“…Abstract The new epibatidine analogue exo-2-(2-pyridyl)-7-azabicyclo[2.2.1]heptane (2PABH) was synthesised. Separation of enantiomers was performed on chiral…”
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