Search Results - "Patrick Schenck, L."

Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue by Cotton, James A, Motta, Jean-Paul, Schenck, L Patrick, Hirota, Simon A, Beck, Paul L, Buret, Andre G

“…Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a predominant cause of waterborne diarrheal disease that may lead to post-infectious functional…”
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Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome by Ng, Jeffrey, Hirota, Simon A, Gross, Olaf, Li, Yan, Ulke–Lemee, Annegret, Potentier, Mireille S, Schenck, L. Patrick, Vilaysane, Akosua, Seamone, Mark E, Feng, Hanping, Armstrong, Glen D, Tschopp, Jurg, MacDonald, Justin A, Muruve, Daniel A, Beck, Paul L

“…Background & Aims Clostridium difficile –associated disease (CDAD) is the leading cause of nosocomial diarrhea in the United States. C difficile toxins TcdA…”
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Cigarette smoke exposure attenuates the induction of antigen-specific IgA in the murine upper respiratory tract by McGrath, Joshua J. C., Thayaparan, Danya, Cass, Steven P., Mapletoft, Jonathan P., Zeng, Peter Y. F., Koenig, Joshua F. E., Fantauzzi, Matthew F., Bagri, Puja, Ly, Bruce, Heo, Rachel, Schenck, L. Patrick, Shen, Pamela, Miller, Matthew S., Stämpfli, Martin R.

“…The upper respiratory tract is highly exposed to airborne pathogens and serves as an important inductive site for protective antibody responses, including…”
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The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction by Hansen, Ashleigh, Alston, Laurie, Tulk, Sarah E, Schenck, L Patrick, Grassie, Michael E, Alhassan, Basmah F, Veermalla, Arun Teja, Al-Bashir, Samir, Gendron, Fernand-Pierre, Altier, Christophe, MacDonald, Justin A, Beck, Paul L, Hirota, Simon A

“…C. difficile is a Gram-positive spore-forming anaerobic bacterium that is the leading cause of nosocomial diarrhea in the developed world. The pathogenesis of…”
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The Src kinase Fyn is protective in acute chemical‐induced colitis and promotes recovery from disease by Lopes, Fernando, Wang, Arthur, Smyth, David, Reyes, Jose‐Luis, Doering, Axinia, Schenck, L. Patrick, Beck, Paul, Waterhouse, Christopher, McKay, Derek M.

“…Absence of Fyn kinase results in greater DSS‐induced disease; leukocyte Fyn kinase is beneficial in limiting colitis. Despite progress in understanding enteric…”
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Nasal Tissue Extraction Is Essential for Characterization of the Murine Upper Respiratory Tract Microbiota by Schenck, L Patrick, McGrath, Joshua J C, Lamarche, Daphnée, Stämpfli, Martin R, Bowdish, Dawn M E, Surette, Michael G

“…Respiratory infections are a leading cause of morbidity and mortality worldwide. Bacterial pathogens often colonize the upper respiratory tract (nose or mouth)…”
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Intrarectal Instillation of Clostridium difficile Toxin A Triggers Colonic Inflammation and Tissue Damage: Development of a Novel and Efficient Mouse Model of Clostridium difficile Toxin Exposure by HIROTA, Simon A, LABLOKOV, Vadim, YAN LI, BOLSTAD, Jeff, MULVEY, George L, ARMSTRONG, Glen D, MACNAUGHTON, Wallace K, MURUVE, Daniel A, MACDONAID, Justin A, BECK, Paul L, TULK, Sarah E, SCHENCK, L. Patrick, BECKER, Helen, NGUYEN, Jimmie, AL BASHIR, Samir, DINGLE, Tanis C, LAING, Austin, JIANRUI LIU

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Attenuation of Clostridium difficile toxin‐induced damage to epithelial barrier by ecto‐5′‐nucleotidase (CD73) and adenosine receptor signaling by Patrick Schenck, L., Hirota, S. A., Hirota, C. L., Boasquevisque, P., Tulk, S. E., Li, Y., Wadhwani, A., Doktorchik, C. T. A., MacNaughton, W. K., Beck, P. L., MacDonald, J. A.

“…Background Clostridium difficile (Cdf) releases toxins (TcdA and TcdB) that damage the intestinal epithelial barrier. Ecto‐5′‐nucleotidase (CD73) is expressed…”
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Exaggerated IL-15 and Altered Expression of foxp3+ Cell-Derived Cytokines Contribute to Enhanced Colitis in Nlrp3−/− Mice by MacDonald, Justin A., Beck, Paul L., Muruve, Daniel A., Li, Yan, Potentier, Mireille S., Schenck, L. Patrick, Becker, Helen M., Tulk, Sarah E., Ueno, Aito, Hirota, Simon A., Ghosh, Subrata

“…The pathogenesis of Crohn’s disease (CD) involves defects in the innate immune system, impairing responses to microbes. Studies have revealed that mutations…”
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Gastrointestinal dysbiosis and the use of fecal microbial transplantation in Clostridium difficile infection by Schenck, L Patrick, Beck, Paul L, MacDonald, Justin A

“…The impact of antibiotics on the human gut microbiota is a significant concern. Antibiotic-associated diarrhea has been on the rise for the past few decades…”
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Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice by Shen, Pamela, Whelan, Fiona J, Schenck, L Patrick, McGrath, Joshua J C, Vanderstocken, Gilles, Bowdish, Dawn M E, Surette, Michael G, Stämpfli, Martin R

“…Smokers have nasal microbiota dysbiosis, with an increased frequency of colonizing bacterial pathogens. It is possible that cigarette smoke increases pathogen…”
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Streptococcus pneumoniae Colonization Is Required To Alter the Nasal Microbiota in Cigarette Smoke-Exposed Mice by Shen, Pamela, Whelan, Fiona J., Schenck, L. Patrick, McGrath, Joshua J. C., Vanderstocken, Gilles, Bowdish, Dawn M. E., Surette, Michael G., Stämpfli, Martin R.

“…Smokers have nasal microbiota dysbiosis, with an increased frequency of colonizing bacterial pathogens. It is possible that cigarette smoke increases pathogen…”
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Giardia duodenalis Infection Reduces Granulocyte Infiltration in an In Vivo Model of Bacterial Toxin-Induced Colitis and Attenuates Inflammation in Human Intestinal Tissue: e109087 by Cotton, James A, Motta, Jean-Paul, Schenck, L Patrick, Hirota, Simon A, Beck, Paul L, Buret, Andre G

“…Giardia duodenalis (syn. G. intestinalis, G. lamblia) is a predominant cause of waterborne diarrheal disease that may lead to post-infectious functional…”
Get full text

The P2Y6 Receptor Mediates Clostridium difficile Toxin-Induced CXCL8/IL-8 Production and Intestinal Epithelial Barrier Dysfunction: e81491 by Hansen, Ashleigh, Alston, Laurie, Tulk, Sarah E, Schenck, L Patrick, Grassie, Michael E, Alhassan, Basmah F, Veermalla, Arun Teja, Al-Bashir, Samir, Gendron, Fernand-Pierre, Altier, Christophe

“…C. difficile is a Gram-positive spore-forming anaerobic bacterium that is the leading cause of nosocomial diarrhea in the developed world. The pathogenesis of…”
Get full text