Search Results - "Patrick R. Shiflett"

Modeling of receptor mimics that inhibit superantigen pathogenesis by Möllhoff, Margit, Zanden, Hannah B. Vander, Shiflett, Patrick R., Gupta, Goutam

“…Staphylococcal enterotoxins SEB and SEC3 and toxic shock syndrome toxin TSST‐1 act as superantigens by overstimulating the human immune system and thereby…”
Get full text

Structural Studies on the Hairpins at the 3‘ Untranslated Region of an Anthrax Toxin Gene by Shiflett, Patrick R., Taylor-McCabe, Kirsten J., Michalczyk, Ryszard, Silks, Louis A. “Pete”, Gupta, Goutam

“…Three proteins, namely, protective antigen (PA), edema factor (EF), and lethal factor (LF), encoded by the pX01 plasmid of Bacillus anthracis play a major role…”
Get full text

Structure-Based Design of a Bispecific Receptor Mimic That Inhibits T Cell Responses to a Superantigen by Lehnert, Nancy M, Allen, David L, Allen, Beth L, Catasti, Paolo, Shiflett, Patrick R, Chen, Michael, Lehnert, Bruce E, Gupta, Goutam

“…Key surface proteins of pathogens and their toxins bind to the host cell receptors in a manner that is quite different from the way the natural ligands bind to…”
Get full text

Design of chimeric receptor mimics with different TcRVbeta isoforms. Type-specific inhibition of superantigen pathogenesis by Hong-Geller, Elizabeth, Möllhoff, Margit, Shiflett, Patrick R, Gupta, Goutam

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
Get full text

Design of Chimeric Receptor Mimics with Different TcRVβ Isoforms by Hong-Geller, Elizabeth, Möllhoff, Margit, Shiflett, Patrick R., Gupta, Goutam

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
Get full text

Design of Chimeric Receptor Mimics with Different TcRVβ Isoforms by Elizabeth Hong-Geller, Margit Möllhoff, Patrick R. Shiflett, Goutam Gupta

“…The Staphylococcus aureus enterotoxins (S.E.) A-I, and toxic-shock syndrome toxin TSST-1 act as superantigens to cause overstimulation of the host immune…”
Get full text

Modeling of receptor mimics that inhibit superantigen pathogenesis: MODELING OF RECEPTOR MIMICS by Möllhoff, Margit, Zanden, Hannah B. Vander, Shiflett, Patrick R., Gupta, Goutam

Get full text