Search Results - "Patriarca, Eduardo J"
-
1
Proline Metabolism in Tumor Growth and Metastatic Progression
Published in Frontiers in oncology (15-05-2020)“…Cancer cells show a formidable capacity to survive under stringent conditions, to elude mechanisms of control, such as apoptosis, and to resist therapy. Cancer…”
Get full text
Journal Article -
2
The Multifaceted Roles of Proline in Cell Behavior
Published in Frontiers in cell and developmental biology (12-08-2021)“…Herein, we review the multifaceted roles of proline in cell biology. This peculiar cyclic imino acid is: (i) A main precursor of extracellular collagens (the…”
Get full text
Journal Article -
3
Nanoengineered Surfaces for Focal Adhesion Guidance Trigger Mesenchymal Stem Cell Self-Organization and Tenogenesis
Published in Nano letters (11-03-2015)“…The initial conditions for morphogenesis trigger a cascade of events that ultimately dictate structure and functions of tissues and organs. Here we report that…”
Get full text
Journal Article -
4
Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
Published in Nature communications (02-09-2016)“…Known molecular determinants of developmental plasticity are mainly transcription factors, while the extrinsic regulation of this process has been largely…”
Get full text
Journal Article -
5
6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice
Published in Scientific reports (02-12-2019)“…Dystrophies are characterized by progressive skeletal muscle degeneration and weakness as consequence of their molecular abnormalities. Thus, new drugs for…”
Get full text
Journal Article -
6
L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation
Published in Stem cell reports (15-10-2013)“…Metabolites are emerging as key mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. We found that the…”
Get full text
Journal Article -
7
Metabolic-Epigenetic Axis in Pluripotent State Transitions
Published in Epigenomes (31-07-2019)“…Cell state transition (CST) occurs during embryo development and in adult life in response to different stimuli and is associated with extensive epigenetic…”
Get full text
Journal Article -
8
Vitamin C and l-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum
Published in Stem cell reports (10-01-2017)“…Metabolites and cofactors are emerging as key regulators of cell plasticity and reprogramming, and their role in the control of pluripotency is just being…”
Get full text
Journal Article -
9
Glutathione Is Required by Rhizobium etli for Glutamine Utilization and Symbiotic Effectiveness
Published in Molecular plant-microbe interactions (01-03-2012)“…Here, we provide genetic and biochemical evidence indicating that the ability of Rhizobium etli bacteria to efficiently catabolize glutamine depends on its…”
Get full text
Journal Article -
10
Generation of Gastruloids from Epiblast-Like Cells
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…The different states of mouse pluripotency described so far rely on a combination of molecular, phenotypic, and functional analysis. Embryonic Stem cells…”
Get more information
Journal Article -
11
Key Role of Bacterial NH4+ Metabolism in Rhizobium-Plant Symbiosis
Published in Microbiology and Molecular Biology Reviews (01-06-2002)“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
12
Generation of Epiblast-Like Cells
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…Different states of pluripotency can be captured in vitro depending on the embryo stage from which they are derived and the culture conditions. Pluripotency is…”
Get more information
Journal Article -
13
Collagen Prolyl Hydroxylation-Dependent Metabolic Perturbation Governs Epigenetic Remodeling and Mesenchymal Transition in Pluripotent and Cancer Cells
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Collagen prolyl hydroxylation (CPH), which is catalyzed by prolyl 4-hydroxylase (P4H), is the most prevalent posttranslational modification in humans and…”
Get full text
Journal Article -
14
CRIPTO-based micro-heterogeneity of mouse muscle satellite cells enables adaptive response to regenerative microenvironment
Published in Developmental cell (18-12-2023)“…Skeletal muscle repair relies on heterogeneous populations of satellite cells (SCs). The mechanisms that regulate SC homeostasis and state transition during…”
Get more information
Journal Article -
15
An Alternative Succinate (2-Oxoglutarate) Transport System in Rhizobium tropici Is Induced in Nodules of Phaseolus vulgaris
Published in Journal of Bacteriology (01-08-2009)“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
16
Development of ectopic roots from abortive nodule primordia
Published in Molecular plant-microbe interactions (01-10-2004)“…The symbiotic phenotype of five Tn5-induced mutants of Rhizobium etli affected in different anabolic pathways (namely, gluconeogenesis and biosynthesis of…”
Get full text
Journal Article -
17
Functional characterization of an ammonium transporter gene from Lotus japonicus
Published in Gene (30-05-2001)“…NH(4)(+) is the main product of symbiotic nitrogen fixation and the external concentration of combined nitrogen plays a key regulatory role in all the…”
Get full text
Journal Article -
18
Phenotype characterization of human melanoma cells resistant to dabrafenib
Published in Oncology reports (01-11-2017)“…In the present study, the phenotype of melanoma cells resistant to dabrafenib (a B-RAF inhibitor) was investigated, to shed more light on melanoma resistance…”
Get full text
Journal Article -
19
Publisher Correction: 6-Bromoindirubin-3′-oxime intercepts GSK3 signaling to promote and enhance skeletal muscle differentiation affecting miR-206 expression in mice
Published in Scientific reports (19-06-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text
Journal Article -
20
c-Myc modulation: a key role in melanoma drug response
Published in Cancer biology & therapy (02-09-2015)“…Understanding molecular mechanisms involved in melanoma resistance to drugs is a big challenge. Experimental evidences suggested a correlation between…”
Get full text
Journal Article