Search Results - "Patrene, K D"

Bone Marrow as a Potential Source of Hepatic Oval Cells by Petersen, B. E., Bowen, W. C., Patrene, K. D., Mars, W. M., Sullivan, A. K., Murase, N., Boggs, S. S., Greenberger, J. S., Goff, J. P.

“…Bone marrow stem cells develop into hematopoietic and mesenchymal lineages but have not been known to participate in production of hepatocytes, biliary cells,…”
Get full text

A nonlethal conditioning approach to achieve durable multilineage mixed chimerism and tolerance across major, minor, and hematopoietic histocompatibility barriers by Colson, YL, Wren, SM, Schuchert, MJ, Patrene, KD, Johnson, PC, Boggs, SS, Ildstad, ST

“…Reconstitution of lethally irradiated mice with a mixture of syngeneic and allogeneic (A+B-->A) bone marrow results in multilineage mixed allogeneic chimerism,…”
Get full text

Constitutive systemic expression of IL-1Ra or soluble TNF receptor by genetically modified hematopoietic cells suppresses LPS induction of IL-6 and IL-10 by DOUGHTY, L. A, PATRENE, K. D, EVANS, C. H, BOGGS, S. S, ROBBINS, P. D

“…We have been developing both local and systemic gene therapy approaches to treat inflammatory and autoimmune diseases. To determine if systemic, constitutive…”
Get full text

Role of CD44 in the development of natural killer cells from precursors in long-term cultures of mouse bone marrow by Delfino, DV, Patrene, KD, DeLeo, AB, DeLeo, R, Herberman, RB, Boggs, SS

“…The role of the adhesion molecule CD44 in the development of NK cells was analyzed in a mouse long-term bone marrow culture system. After 4 wk of culture (day…”
Get full text

Purified murine hematopoietic stem cells function longer on nonirradiated W41/Wv than on +/+ irradiated stroma by VECCHINI, F, PATRENE, K. D, BOGGS, S. S

“…Mouse bone marrow (BM) was separated into low-density, lineage-negative, wheat germ agglutinin-positive (WGA+), Rhodamine-123 bright (Rhbright) or dim (Rhdim)…”
Get full text

Short-term myeloid reconstitution following TBI is not adversely affected by doses of FK506 that abrogate lethal GVHD by Cooper, M H, Patrene, K D, Vecchini, F, Austin, C A, Markus, P M, Boggs, S S

“…Studies were undertaken to determine whether the doses of FK506 that are effective for acute GVHD prophylaxis following lethal irradiation and bone marrow…”
Get more information

Hematopoiesis and aging III: Anemia and a blunted erythropoietic response to hemorrhage in aged mice by Boggs, D R, Patrene, K D

“…Whether the hematocrit normally declines in the aged or whether such a decline represents inapparent disease in addition to aging is a matter of dispute…”
Get more information

Durable mixed allogeneic chimerism and tolerance by a nonlethal radiation-based cytoreductive approach by Colson, YL, Li, H, Boggs, SS, Patrene, KD, Johnson, PC, Ildstad, ST

“…For over 40 years, the association between hemopoietic chimerism and donor-specific tolerance for allografts has been recognized. However, toxicity associated…”
Get full text

Mixed allogeneic chimerism induced by a sublethal approach prevents autoimmune diabetes and reverses insulitis in nonobese diabetic (NOD) mice by Li, H, Kaufman, CL, Boggs, SS, Johnson, PC, Patrene, KD, Ildstad, ST

“…Evidence in experimental models suggests that many autoimmune diseases can be prevented by transplantation of bone marrow from disease-resistant donors. For…”
Get full text

16,16-Dimethyl prostaglandin E2 and/or syngeneic bone marrow transplantation increase mouse survival after supra-lethal total body irradiation by Berk, L B, Patrene, K D, Boggs, S S

“…We evaluated the effects of 16,16-dimethyl prostaglandin E2 (dm-PGE2), with and without syngeneic bone marrow transplantation (BMT) on the survival and…”
Get more information

Generation of natural killer cells from long-term cultures of mouse bone marrow by Vecchini, F, Delfino, D, Patrene, K D, DeLeo, A, Lu, L, Herberman, R B, Boggs, S S

“…The features of a mouse long-term bone marrow culture (LTBMC) system that produces natural killer (NK) cell activity are described. Over a 4-week period in the…”
Get more information

Alterations of nuclear size profiles in AKR/J mice with spontaneous or transplanted leukemia by Schwartz, G N, Patrene, K D, Boggs, S S

“…Electronic sizing with a Coulter Counter was used to measure the frequency and number of cells with a large nuclear volume in tissues from AKR/J mice with…”
Get more information

Marrow mass and distribution in murine skeletons cleaned by beetles as compared to cut up carcasses and a further simplification of the latter technique by Boggs, D R, Patrene, K D

“…Distribution of 59Fe into various bone groups of the complete murine skeleton was studied using two methods of dividing up the bones: 1) our previously…”
Get more information

The effect of DFMO induced uptake of [3H] putrescine on human glioma cells by REDGATE, Edward S, ALEXANDER, Dominic, MAGRA, T. Ryan, HENRETTY, Joseph S, PATRENE, Kenneth D, BOGGS, Sallie S

“…Polyamine synthesis inhibitors, such as a-difluoromethylornithine (DFMO), inhibit tumor cell growth in vitro and in vivo. However, upon cessation of treatment,…”
Get full text

Characterization of the stage in natural killer cell development in 14.5-day mouse fetal liver using adult bone marrow stroma by Lu, Jing, Patrene, Kenneth D, Appasamy, Pierette M, Herberman, Ronald B, Boggs, Sallie S

“…Nonstimulated fetal liver (FL) from 14.5-day gestation mice had no natural killer (NK) cell activity and <3% expressed NK1.1. Even after short-term (3–4 day)…”
Get full text

Expression of murine CD34 by fetal liver NK cell progenitors by Lu, Jing, Patrene, Kenneth D, Herberman, Ronald B, Boggs, Sallie S

“…Although 14.5-day murine fetal liver (FL) has few, if any, mature natural killer (NK) cells, culture of FL with recombinant human IL-2 (rhIL-2) and stroma from…”
Get full text

Natural killer cell precursors in the CD44neg/dim T-cell receptor population of mouse bone marrow by Delfino, D V, Patrene, K D, Lu, J, Deleo, A, Deleo, R, Herberman, R B, Boggs, S S

“…Natural killer (NK) cells develop from the nonadherent cell component of NK long-term bone marrow (BM) cultures (NK-LTBMC). Because these nonadherent cells are…”
Get full text

A minimal conditioning approach to achieve stable multilineage mouse plus rat chimerism by Abou El-Ezz, A.Y., Boggs, S.S., Johnson, P.C., Li, Hua, Patrene, K.D., Itskowitz, M.S., Kaufman, C.L., Ildstad, S.T.

“…Transplantation of untreated rat bone marrow into lethally irradiated (950 cGy) mouse recipients results in durable xenogeneic (rat→mouse) chimerism and…”
Get full text

The effect of syngeneic marrow injection upon recovery in sub- and near-lethally irradiated mice by Boggs, S S, Boggs, D R, Patrene, K D

“…Mice were given sub-lethal (200-600 cGy) or near-lethal (800 cGy) whole body irradiation and the effect of injecting syngeneic marrow on subsequent…”
Get more information

Fetal Liver Cells Transplanted in Utero Rescue the Osteopetrotic Phenotype in the oc/oc Mouse by Tondelli, Barbara, Blair, Harry C, Guerrini, Matteo, Patrene, Kenneth D, Cassani, Barbara, Vezzoni, Paolo, Lucchini, Franco

“…Autosomal recessive osteopetrosis (ARO) is a group of genetic disorders that involve defects that preclude the normal function of osteoclasts, which…”
Get full text