Search Results - "Patman, Gillian L"
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1
The rate of production of uric acid by hepatocytes is a sensitive index of compromised cell ATP homeostasis
Published in American journal of physiology: endocrinology and metabolism (15-11-2013)“…Plasma levels of uric acid, the final product of purine degradation in humans, are elevated in metabolic syndrome and are strongly associated with insulin…”
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2
Post-transcriptional activation of PPAR alpha by KLF6 in hepatic steatosis
Published in Journal of hepatology (01-05-2013)“…Background & Aims Dysregulated glucose homeostasis and lipid accumulation characterize non-alcoholic fatty liver disease (NAFLD), but underlying mechanisms are…”
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3
Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-04-2012)“…The polymorphism, KLF6‐IVS1‐27A, in the Krüppel‐like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is…”
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4
Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma?
Published in Liver cancer (Basel ) (01-12-2022)“…Abstract Introduction: Heparin sulphate proteoglycans in the liver tumour microenvironment (TME) are key regulators of cell signalling, modulated by…”
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5
A proteomic strategy to identify novel serum biomarkers for liver cirrhosis and hepatocellular cancer in individuals with fatty liver disease
Published in BMC cancer (05-08-2009)“…Non-alcoholic fatty liver disease (NAFLD) has a prevalence of over 20% in Western societies. Affected individuals are at risk of developing both cirrhosis and…”
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6
Glucokinase links Krueppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-04-2012)“…The polymorphism, KLF6-IVS1-27A, in the Krueppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is…”
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Journal Article -
7
Glucokinase links Krüppel-like factor 6 to the regulation of hepatic insulin sensitivity in non-alcoholic fatty liver disease
Published in Hepatology (Baltimore, Md.) (01-03-2012)“…The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is…”
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Journal Article