Search Results - "Patiño, Ana"
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Phase I Trial of DNX-2401 for Diffuse Intrinsic Pontine Glioma Newly Diagnosed in Pediatric Patients
Published in Neurosurgery (01-11-2018)“…Abstract BACKGROUND There are no effective treatments for diffuse intrinsic pontine gliomas (DIPGs); these tumors cannot be surgical resected, and diagnosis is…”
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Wnt signaling and Loxl2 promote aggressive osteosarcoma
Published in Cell research (01-10-2020)“…Osteosarcoma (OS) is the most frequent primary malignant bone tumor in urgent need of better therapies. Using genetically modified mouse models (GEMMs), we…”
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Primary trimethylaminuria syndrome: more than an unpleasant odor
Published in International journal of dermatology (01-03-2023)Get full text
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Identification of mutations associated with acquired resistance to sunitinib in renal cell cancer
Published in International journal of cancer (01-10-2019)“…Sunitinib is one of the most widely used targeted therapeutics for renal cell carcinoma (RCC), but acquired resistance against targeted therapies remains a…”
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Reduced dengue incidence following city-wide wMel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study
Published in PLoS neglected tropical diseases (30-11-2023)“…The introduction of Wolbachia (wMel strain) into Aedes aegypti mosquitoes reduces their capacity to transmit dengue and other arboviruses. Randomised and…”
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Zn-Salphen Acrylic Films Powered by Aggregation-Induced Enhanced Emission for Sensing Applications
Published in Journal of fluorescence (01-07-2024)“…Zn(II) complexes possess attractive characteristics for supramolecular chemistry, catalysis, and optoelectronic applications, while Zn-Salphen counterparts are…”
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CYR61 triggers osteosarcoma metastatic spreading via an IGF1Rβ-dependent EMT-like process
Published in BMC cancer (14-01-2019)“…Osteosarcoma is the most prevalent primary bone malignancy in children and young adults. These tumors are highly metastatic, leading to poor outcome. We…”
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The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma
Published in Clinical cancer research (01-05-2016)“…Osteosarcoma is the most common malignant bone tumor in children and adolescents. Despite aggressive chemotherapy, more than 30% of patients do not respond and…”
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Prospective assessment of diagnostic tests for pediatric penicillin allergy: From clinical history to challenge tests
Published in Annals of allergy, asthma, & immunology (01-08-2018)“…Diagnostic guidelines for penicillin allergy in children recommend cumbersome protocols based partially on data from adults, which may be suboptimal for…”
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Building on the clinical applicability of ctDNA analysis in non-metastatic pancreatic ductal adenocarcinoma
Published in Scientific reports (13-07-2024)“…Pancreatic ductal adenocarcinoma represents one of the solid tumors showing the worst prognosis worldwide, with a high recurrence rate after adjuvant or…”
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A cumulative effect involving malfunction of the PTH1R and ATP4A genes explains a familial gastric neuroendocrine tumor with hypothyroidism and arthritis
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-11-2017)“…Background Type I gastric neuroendocrine tumors (gNETs) classically arise because of hypergastrinemia and involve destruction of parietal cells, which are…”
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Identification of germline cancer predisposition variants in pediatric sarcoma patients from somatic tumor testing
Published in Scientific reports (20-02-2023)“…Genetic predisposition is an important risk factor for cancer in children and adolescents but detailed associations of individual genetic mutations to…”
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Self-reported perceptions and knowledge of telemedicine in medical students and professionals who enrolled in an online course in Peru
Published in BMC medical education (03-02-2023)“…Telemedicine has become more relevant during the COVID-19 pandemic. However, medical students and professionals do not acquire competences in telemedicine…”
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Matrix-Gla protein promotes osteosarcoma lung metastasis and associates with poor prognosis
Published in The Journal of pathology (01-08-2016)“…Osteosarcoma (OS) is the most prevalent osseous tumour in children and adolescents and, within this, lung metastases remain one of the factors associated with…”
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Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01
Published in PloS one (01-01-2016)“…Despite the recent advances in the development of antitumor therapies, the prognosis for patients with malignant gliomas remains dismal. Therapy with…”
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Reduced dengue incidence following city-wide w Mel Wolbachia mosquito releases throughout three Colombian cities: Interrupted time series analysis and a prospective case-control study
Published in PLoS neglected tropical diseases (01-11-2023)“…BackgroundThe introduction of Wolbachia (wMel strain) into Aedes aegypti mosquitoes reduces their capacity to transmit dengue and other arboviruses. Randomised…”
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Methotrexate in Pediatric Osteosarcoma: Response and Toxicity in Relation to Genetic Polymorphisms and Dihydrofolate Reductase and Reduced Folate Carrier 1 Expression
Published in The Journal of pediatrics (01-05-2009)“…Objective To determine the influence of the genotype and the level of expression of different enzymes involved in folate metabolism on the response to and…”
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Effect of ABCB1 and ABCC3 polymorphisms on osteosarcoma survival after chemotherapy: a pharmacogenetic study
Published in PloS one (07-10-2011)“…Standard treatment for osteosarcoma patients consists of a combination of cisplatin, adriamycin, and methotrexate before surgical resection of the primary…”
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DNX-2401, an Oncolytic Virus, for the Treatment of Newly Diagnosed Diffuse Intrinsic Pontine Gliomas: A Case Report
Published in Frontiers in oncology (12-03-2018)“…Diffuse intrinsic pontine gliomas (DIPGs) are aggressive glial brain tumors that primarily affect children, for which there is no curative treatment. Median…”
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