Search Results - "Patil, Suyash M"
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Microbes as Medicines: Harnessing the Power of Bacteria in Advancing Cancer Treatment
Published in International journal of molecular sciences (14-10-2020)“…Conventional anti-cancer therapy involves the use of chemical chemotherapeutics and radiation and are often non-specific in action. The development of drug…”
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An Overview of Nanocarrier-Based Adjuvants for Vaccine Delivery
Published in Pharmaceutics (27-03-2021)“…The development of vaccines is one of the most significant medical accomplishments which has helped to eradicate a large number of diseases. It has undergone…”
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Design of Experiment (DoE) Approach for Developing Inhalable PLGA Microparticles Loaded with Clofazimine for Tuberculosis Treatment
Published in Pharmaceuticals (Basel, Switzerland) (07-06-2024)“…Tuberculosis (TB) is an airborne bacterial infection caused by ( ), resulting in approximately 1.3 million deaths in 2022 worldwide. Oral therapy with anti-TB…”
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Exosomes as drug delivery systems: A brief overview and progress update
Published in European journal of pharmaceutics and biopharmaceutics (01-09-2020)“…[Display omitted] Exosomes are intracellular membrane-based vesicles with diverse compositions that are involved in biological and pathological processes…”
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Nisin ZP, an Antimicrobial Peptide, Induces Cell Death and Inhibits Non-Small Cell Lung Cancer (NSCLC) Progression in vitro in 2D and 3D Cell Culture
Published in Pharmaceutical research (01-11-2022)“…Lung cancer is the leading cause of cancer deaths globally with most of the reported cases (> 85%) associated with non-small cell lung cancer (NSCLC). Current…”
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Inhalable bedaquiline-loaded cubosomes for the treatment of non-small cell lung cancer (NSCLC)
Published in International journal of pharmaceutics (25-09-2021)“…[Display omitted] •Bedaquiline-loaded cubosomes (BQLC) displayed excellent particle size, zeta potential, and aerosolization behavior suitable for NSCLC…”
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Aerosolized nanoliposomal carrier of remdesivir: an effective alternative for COVID-19 treatment in vitro
Published in Nanomedicine (London, England) (01-06-2021)“…To formulate an aerosolized nanoliposomal carrier for remdesivir (AL-Rem) against coronavirus disease 2019. AL-Rem was prepared using modified hydration…”
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Anticancer activity of D-LAK-120A, an antimicrobial peptide, in non-small cell lung cancer (NSCLC)
Published in Biochimie (01-10-2022)“…Non-small cell lung cancer (NSCLC) is a major cause of global cancer mortalities and accounts for approximately 80–85% of reported lung cancer cases…”
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A quality-by-design strategic approach for the development of bedaquiline-pretomanid nanoparticles as inhalable dry powders for TB treatment
Published in International journal of pharmaceutics (25-03-2024)“…[Display omitted] Tuberculosis (TB) is caused by Mycobacterium tuberculosis (M.tb) and is the second leading cause of death from an infectious disease…”
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Oral inhalation of dacomitinib nanocarriers as a therapeutic strategy for non-small cell lung cancer
Published in Nanomedicine (London, England) (20-08-2024)“…Development of an inhalable nanoformulation of dacomitinib (DMB) encapsulated in poly-(lactic-co-glycolic acid) nanoparticles (NPs) to improve solubility,…”
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Pulmonary delivery of spray-dried Nisin ZP antimicrobial peptide for non-small cell lung cancer (NSCLC) treatment
Published in International journal of pharmaceutics (05-03-2023)“…[Display omitted] Nisin ZP is an antimicrobial peptide (AMP) produced by the bacterium Lactococcus lactis, and we have previously demonstrated anticancer…”
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Pulmonary delivery of osimertinib liposomes for non-small cell lung cancer treatment: formulation development and in vitro evaluation
Published in Drug delivery and translational research (01-10-2022)“…Osimertinib (OB) is a third-generation irreversible tyrosine kinase inhibitor targeting the epidermal growth factor receptor (EGFR), overexpressed in non-small…”
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Solubility Enhancement and Inhalation Delivery of Cyclodextrin-Based Inclusion Complex of Delamanid for Pulmonary Tuberculosis Treatment
Published in AAPS PharmSciTech (26-01-2023)“…Tuberculosis (TB) is a contiguous airborne disease caused by Mycobacterium tuberculosis ( M.tb ), primarily affecting the human lungs. The progression of…”
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