Search Results - "Patil, Shruti V"
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1
A Novel Mouse Model of TGFβ2-Induced Ocular Hypertension Using Lentiviral Gene Delivery
Published in International journal of molecular sciences (21-06-2022)“…Glaucoma is a multifactorial disease leading to irreversible blindness. Primary open-angle glaucoma (POAG) is the most common form and is associated with the…”
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Journal Article -
2
Lentiviral mediated delivery of CRISPR/Cas9 reduces intraocular pressure in a mouse model of myocilin glaucoma
Published in Scientific reports (23-03-2024)“…Mutations in myocilin ( MYOC ) are the leading known genetic cause of primary open-angle glaucoma, responsible for about 4% of all cases. Mutations in MYOC…”
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Journal Article -
3
Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction
Published in Acta neuropathologica communications (18-10-2024)“…The ability to derive retinal ganglion cells (RGCs) from human pluripotent stem cells (hPSCs) has led to numerous advances in the field of retinal research,…”
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Journal Article -
4
Acquisition of neurodegenerative features in isogenic OPTN
Published in Acta neuropathologica communications (18-10-2024)“…The ability to derive retinal ganglion cells (RGCs) from human pluripotent stem cells (hPSCs) has led to numerous advances in the field of retinal research,…”
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Journal Article -
5
Abstract 1947: Combination of Vincristine and Clotam induces antiproliferative response in medulloblastoma cells
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Medulloblastoma (MB) is the most common pediatric malignant brain tumor and usually originates in the cerebellum. These tumors have the propensity to…”
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Journal Article -
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Tolfenamic Acid Enhances the Anti-Proliferative Activity of Vincristine in Medulloblastoma Cell Lines
Published 01-01-2017“…Medulloblastoma (MB) is the most common pediatric malignant brain tumor and usually originates in the cerebellum. These tumors have the propensity to…”
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Dissertation