Search Results - "Patil, Kalpesh R."

Animal Models of Inflammation for Screening of Anti-inflammatory Drugs: Implications for the Discovery and Development of Phytopharmaceuticals by Patil, Kalpesh R, Mahajan, Umesh B, Unger, Banappa S, Goyal, Sameer N, Belemkar, Sateesh, Surana, Sanjay J, Ojha, Shreesh, Patil, Chandragouda R

“…Inflammation is one of the common events in the majority of acute as well as chronic debilitating diseases and represent a chief cause of morbidity in today's…”
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Predicting maximum temperatures over India 10-days ahead using machine learning models by Ratnam, J. V., Behera, Swadhin K., Nonaka, Masami, Martineau, Patrick, Patil, Kalpesh R.

“…In the months of March-June, India experiences high daytime temperatures (Tmax), which sometimes lead to heatwave-like conditions over India. In this study, 10…”
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Pentacyclic Triterpenoids Inhibit IKKβ Mediated Activation of NF-κB Pathway: In Silico and In Vitro Evidences by Patil, Kalpesh R, Mohapatra, Purusottam, Patel, Harun M, Goyal, Sameer N, Ojha, Shreesh, Kundu, Chanakya N, Patil, Chandragouda R

“…Pentacyclic Triterpenoids (PTs) and their analogues as well as derivatives are emerging as important drug leads for various diseases. They act through a…”
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Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review by Patil, Ashwani S., Mahajan, Umesh B., Agrawal, Yogeeta O., Patil, Kalpesh R., Patil, Chandragouda R., Ojha, Shreesh, Sharma, Charu, Goyal, Sameer N.

“…The endocannabinoid system (ECS) is natural physiological system in the humans. The presence of the ECS system involves different roles in body. The…”
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Anti-inflammatory activity of bartogenic acid containing fraction of fruits of Barringtonia racemosa Roxb. in acute and chronic animal models of inflammation by Patil, Kalpesh R., Patil, Chandragouda R.

“…The fruits of Barringtonia racemosa are traditionally used in Indian medicine for the treatment of pain and inflammatory conditions. In this study, a fraction…”
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Deep Learning Models to Predict Sea Surface Temperature in Tohoku Region by Patil, Kalpesh R., Iiyama, Masaaki

“…The prediction of sea surface temperature (SST) is a challenging task, especially for regions with high SST variability. Such predictions are either achieved…”
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RETRACTED ARTICLE: Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats by Magar, Shital, Nayak, Deepika, Mahajan, Umesh B., Patil, Kalpesh R., Shinde, Sachin D., Goyal, Sameer N., Swaminarayan, Shivang, Patil, Chandragouda R., Ojha, Shreesh, Kundu, Chanakya Nath

“…Despite the availability of multiple therapeutic agents, the search for novel pain management of neuropathic pain is still a challenge. Oxidative stress and…”
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Challenges and issues with streptozotocin-induced diabetes – A clinically relevant animal model to understand the diabetes pathogenesis and evaluate therapeutics by Goyal, Sameer N., Reddy, Navya M., Patil, Kalpesh R., Nakhate, Kartik T., Ojha, Shreesh, Patil, Chandragouda R., Agrawal, Yogeeta O.

“…Streptozotocin (STZ) has been extensively used over the last three decades to induce diabetes in various animal species and to help screen for hypoglycemic…”
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D-pinitol attenuates cisplatin-induced nephrotoxicity in rats: Impact on pro-inflammatory cytokines by Vasaikar, Nita, Mahajan, Umesh, Patil, Kalpesh R., Suchal, Kapil, Patil, Chandragouda R., Ojha, Shreesh, Goyal, Sameer N.

“…Cisplatin has been widely used as a first-line agent against various forms of solid cancers. However, nephrotoxicity is the major limiting factor for its…”
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Development and biological evaluation of protective effect of kidney targeted N-acetylated chitosan nanoparticles containing thymoquinone for the treatment of DNA damage in cyclophosphamide-induced haemorrhagic cystitis by Prajapati, Chaitali, Agrawal, Yogeeta O., Agnihotri, Vinit V., Mahajan, Umesh B., Patil, Kalpesh R., Patil, Dipak D., Patil, Chandragouda R.

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Aloin alleviates doxorubicin-induced cardiotoxicity in rats by abrogating oxidative stress and pro-inflammatory cytokines by Birari, Lalit, Wagh, Shivani, Patil, Kalpesh R., Mahajan, Umesh B., Unger, Banappa, Belemkar, Sateesh, Goyal, Sameer N., Ojha, Shreesh, Patil, Chandragouda R.

“…Purpose Aloin, an anthraquinone present in the aloe species, possesses antiangiogenic, chemopreventive and antioxidant properties. It exerts cytotoxicity…”
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Disulfiram and Its Copper Chelate Attenuate Cisplatin-Induced Acute Nephrotoxicity in Rats Via Reduction of Oxidative Stress and Inflammation by Khairnar, Shraddha I., Mahajan, Umesh B., Patil, Kalpesh R., Patel, Harun M., Shinde, Sachin D., Goyal, Sameer N., Belemkar, Sateesh, Ojha, Shreesh, Patil, Chandragouda R.

“…The use of cisplatin (CP) in chemotherapy of resistant cancers is limited due to its dose-dependent nephrotoxicity. Disulfiram (DSF), the aversion therapy for…”
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Aloin protects against arsenic trioxide–induced myocardial membrane damage and release of inflammatory cytokines by Birari, Lalit A., Mahajan, Umesh B., Patil, Kalpesh R., Patil, Dipak D., Bagul, Neha A., Belemkar, Sateesh, Goyal, Sameer N., Ojha, Shreesh, Patil, Chandragouda R.

“…Aloin exerts concentration-dependent pro-oxidant and antioxidant effects when tested in vitro. Such duality of effects has not been investigated through in…”
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Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats by Magar, Shital, Nayak, Deepika, Mahajan, Umesh B, Patil, Kalpesh R, Shinde, Sachin D, Goyal, Sameer N, Swaminarayan, Shivang, Patil, Chandragouda R, Ojha, Shreesh, Kundu, Chanakya Nath

“…Despite the availability of multiple therapeutic agents, the search for novel pain management of neuropathic pain is still a challenge. Oxidative stress and…”
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Phloretin-induced suppression of oxidative and nitrosative stress attenuates doxorubicin-induced cardiotoxicity in rats by Wagh, Shivani S., Patil, Kalpesh R., Mahajan, Umesh B., Bagal, Pradnya D., Wadkar, Avinash R., Bommanhalli, Basavraj, Patil, Prabhakar R., Goyal, Sameer N., Ojha, Shreesh, Patil, Chandragouda R.

“…Objective: To compare the cardioprotective efficacy of equimolar doses (50 mM/kg, p.o.) of phloretin and genistein against doxorubicin-induced cardiotoxicity…”
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Retraction Note: Ultra-diluted Toxicodendron pubescens attenuates pro-inflammatory cytokines and ROS- mediated neuropathic pain in rats by Magar, Shital, Nayak, Deepika, Mahajan, Umesh B., Patil, Kalpesh R., Shinde, Sachin D., Goyal, Sameer N., Swaminarayan, Shivang, Patil, Chandragouda R., Ojha, Shreesh, Kundu, Chanakya Nath

“…This paper has been retracted…”
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Aloin attenuates chronic constriction injury-induced neuropathic pain in rats by inhibiting inflammatory cytokines and oxidative stress by Kale, Aarti S., Wadkar, Avinash R., Mahajan, Umesh B., Birari, Lalit A., Belemkar, Sateesh, Goyal, Sameer N., Ojha, Shreesh, Surana, Sanjay J., Patil, Chandragouda R., Patil, Kalpesh R.

“…Objective: To investigate the effect of aloin against chronic constriction injury (CCI)-induced neuropathic pain in rats. Methods: Rats were randomly divided…”
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Performance overview of an artificial intelligence in biomedics: a systematic approach by Patil, Shashikant, Patil, Kalpesh R., Patil, Chandragouda R., Patil, Smit S.

“…Artificial intelligence and technological advancements are exceptionally influenced the entire society and mankind. Unprecendented and extensive use of social…”
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Past and current perspective on new therapeutic targets for Type-II diabetes by Patil, Pradip D, Mahajan, Umesh B, Patil, Kalpesh R, Chaudhari, Sandip, Patil, Chandragouda R, Agrawal, Yogeeta O, Ojha, Shreesh, Goyal, Sameer N

“…Loss of pancreatic β-cell function is a hallmark of Type-II diabetes mellitus (DM). It is a chronic metabolic disorder that results from defects in both…”
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Chemomodulatory Potential of Bartogenic Acid Against DMBA/Croton Oil Induced Two-Step Skin Carcinogenesis in Mice by Patil, Chandragouda R, Sonara, Bhavin M, Mahajan, Umesh B, Patil, Kalpesh R, Patil, Dipak D, Jadhav, Ramchandra B, Goyal, Sameer N, Ojha, Shreesh

“…fruits are believed to be useful in cancer treatment in Ayurveda, the Indian system of medicine. In present study, bartogenic acid (BA), a triterpenoid…”
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