Search Results - "Patil, Chetan N."

Cardiovascular and Metabolic Consequences of Testosterone Supplements in Young and Old Male Spontaneously Hypertensive Rats: Implications for Testosterone Supplements in Men by Dalmasso, Carolina, Patil, Chetan N., Yanes Cardozo, Licy L., Romero, Damian G., Maranon, Rodrigo O.

“…Background The safety of testosterone supplements in men remains unclear. In the present study, we tested the hypothesis that in young and old male…”
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Pregnancy Protects Hyperandrogenemic Female Rats From Postmenopausal Hypertension by Shawky, Noha M., Patil, Chetan N., Dalmasso, Carolina, Maranon, Rodrigo O., Romero, Damian G., Drummond, Heather, Reckelhoff, Jane F.

“…Polycystic ovary syndrome, the most common endocrine disorder in women of reproductive age, is characterized by hyperandrogenemia, obesity, insulin resistance,…”
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Low-dose testosterone protects against renal ischemia-reperfusion injury by increasing renal IL-10-to-TNF-α ratio and attenuating T-cell infiltration by Patil, Chetan N, Wallace, Kedra, LaMarca, Babbette D, Moulana, Mohadetheh, Lopez-Ruiz, Arnaldo, Soljancic, Andrea, Juncos, Luis A, Grande, Joseph P, Reckelhoff, Jane F

“…Renal ischemia-reperfusion (I/R) in male rats causes reductions in plasma testosterone, and infusion of testosterone 3 h postreperfusion is protective. We…”
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Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet by Patil, Chetan N, Ritter, McKenzie L, Wackman, Kelsey K, Oliveira, Vanessa, Balapattabi, Kirthikaa, Grobe, Connie C, Brozoski, Daniel T, Reho, John J, Nakagawa, Pablo, Mouradian, Jr, Gary C, Kriegel, Alison J, Kwitek, Anne E, Hodges, Matthew R, Segar, Jeffrey L, Sigmund, Curt D, Grobe, Justin L

“…Hypertension characterized by low circulating renin activity accounts for roughly 25%-30% of primary hypertension in humans and can be modeled experimentally…”
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Exploration of cardiometabolic and developmental significance of angiotensinogen expression by cells expressing the leptin receptor or agouti-related peptide by Sapouckey, Sarah A, Morselli, Lisa L, Deng, Guorui, Patil, Chetan N, Balapattabi, Kirthikaa, Oliveira, Vanessa, Claflin, Kristin E, Gomez, Javier, Pearson, Nicole A, Potthoff, Matthew J, Gibson-Corley, Katherine N, Sigmund, Curt D, Grobe, Justin L

“…Angiotensin II (ANG II) receptor (AT ) is expressed in cells of the arcuate nucleus of the hypothalamus that express the leptin receptor ( ) and agouti-related…”
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Consequences of advanced aging on renal function in chronic hyperandrogenemic female rat model: implications for aging women with polycystic ovary syndrome by Patil, Chetan N., Racusen, Lorraine C., Reckelhoff, Jane F.

“…Polycystic ovary syndrome (PCOS) is the most common endocrine and reproductive disorder in premenopausal women, characterized by hyperandrogenemia, metabolic…”
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Identification of a redox-sensitive switch within the JAK2 catalytic domain by Smith, John K., Patil, Chetan N., Patlolla, Srikant, Gunter, Barak W., Booz, George W., Duhé, Roy J.

“…Four cysteine residues (Cys866, Cys917, Cys1094, and Cys1105) have direct roles in cooperatively regulating Janus kinase 2 (JAK2) catalytic activity…”
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Platelet activation and erythrocyte lysis during brief exposure of blood to pathophysiological shear stress in vitro by Majumdar, Suvankar, Patil, Chetan N, Ladner-Threadgill, Tammy, Randolph, Erica, Burgreen, Greg W, Kermode, John C

“…Interaction of von Willebrand factor (VWF) with circulating platelets is the trigger for thrombosis in a region of arterial stenosis. These events are…”
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Metabolic Changes and Growth Impairment in a Rat Model of Juvenile CKD: FR-PO424 by Kriegel, Alison J., Patil, Chetan N., Schwasinger, Emma T.

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Abstract 084: Growth Stress And Cardiorenal Syndrome: Effect Of Renal Insufficiency On Blood Pressure And Cardiac Remodeling In Juvenile Rats by Kriegel, Alison J, Patil, Chetan N, Schwasinger, Emma

“…Abstract only Pediatric patients living with chronic kidney disease (CKD) can experience many of the comorbidities associated with CKD in adults including…”
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CREB and ERK Activation by Leptin and Angiotensin in the GT1‐7 Cell Model by Capillary Electrophoresis‐Based Western Blotting by Balapattabi, Kirthikaa, Patil, Chetan N., Deng, Guorui, Sigmund, Curt D., Grobe, Justin L.

“…Abstract only Leptin (LEP) increases resting energy expenditure in part by decreasing Agouti‐related peptide (Agrp) within the arcuate nucleus (ARC) of the…”
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Abstract P249: ICV Infusion Of AgRP Modulates Feeding Behavior And Energy Expenditure In Mice by Oliveira, Vanessa, Balapattabi, Kirthikaa, Reho, John J, Silva, Sebastiao D, Patil, Chetan N, Sigmund, Curt D, Grobe, Justin L

“…Abstract only A subset of Agouti-related protein (AgRP) neurons within the arcuate nucleus express angiotensin type 1a receptors (AT1A), and genetic ablation…”
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Assessing the Effects of Leptin and Angiotensin II Upon Expression of Agouti‐Related Peptide in the GT1‐7 Cell Model by Hei, Megan Vande, Patil, Chetan N., Sapouckey, Sarah A., Balapattabi, Kirthikaa, Oliveira, Vanessa, Deng, Guorui, Grobe, Justin L.

“…Abstract only Leptin acts at its receptor (Lepr) within the arcuate nucleus of the hypothalamus (ARC) to reduce feeding behavior and increase resting metabolic…”
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Abstract P239: Diet Modifies Cardiometabolic Effects Of DOCA-salt In C57BL/6J Mice by Patil, Chetan N, Oliveira, Vanessa, Opichka, Megan, Ritter, McKenzie L, Reho, John J, Segar, Jeffrey L, Sigmund, Curt D, Grobe, Justin L

“…Abstract only The deoxycorticosterone acetate (DOCA)-salt model of hypertension is widely used to investigate the neurohormonal regulation of blood pressure…”
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Common Laboratory Chow Diets Differentially Affect Energy Homeostasis and Modify Metabolic and Electrolyte Balance Effects of DOCA‐salt in Wildtype Mice by Patil, Chetan N., Oliveira, Vanessa, Balapattabi, Kirthikaa, Hei, Megan Vande, Saravia, Fatima, Wackman, Kelsey, Reho, John J., Kirby, John R., Sigmund, Curt D., Grobe, Justin L.

“…Abstract only Roughly 27% of humans with essential hypertension (HTN) exhibit low circulating renin, and this condition is experimentally modeled by…”
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Chronic Low‐Dose ICV Infusion of Agrp in Mice May Suppress Indices of Resting Metabolism in Brown Adipose Tissue Independent of Effects on Feeding Behavior by Oliveira, Vanessa, Balapattabi, Kirthikaa, Patil, Chetan N., Hei, Megan Vande, Silva, Sebastião D., Reho, John J., Sigmund, Curt D., Grobe, Justin L.

“…Abstract only Agouti‐related peptide (Agrp) acts within in the central nervous system to stimulate feeding behavior and suppress energy expenditure, which…”
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Abstract P259: Characterization of Hyperandrogenemic Female Rats With History of Pregnancy by Patil, Chetan N, Dalmasso, Carolina, Maranon, Rodrigo O, Reckelhoff, Jane F

“…Abstract only Women with polycystic ovarian syndrome (PCOS) experience hyperandrogenemia, elevated MAP, irregular menses, and difficulty becoming pregnant. As…”
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Abstract P167: Aging Exacerbates Increased MAP and Proteinuria in Male Rat Offspring of Hyperandrogenemic Mothers by Dalmasso, Carolina, Maranon, Rodrigo O, Patil, Chetan N, Reckelhoff, Jane F

“…Abstract only Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 6-10 % of women, and is associated with hyperandrogenemia,…”
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Study of Acute Kidney Injury in hyperandrogenemic female rats by Patil, Chetan N, Dalmasso, Carolina, Maranon, Rodrigo O., Yanes Cardozo, Licy L., Reckelhoff, Jane F.

“…Abstract only Chronic hyperandrogenemia is hallmark of polycystic ovarian syndrome (PCOS), affecting ~10% of women of reproductive age. Compared to men, women…”
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Maternal Hyperandrogenemia Causes Increased MAP and Proteinuria in Male Rat Offspring by Dalmasso, Carolina, Maranon, Rodrigo O., Patil, Chetan N., Reckelhoff, Jane F.

“…Abstract only Polycystic ovary syndrome (PCOS) is a common endocrine disorder affecting 6–10 % of women, and is associated with hyperandrogenemia,…”
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