Search Results - "Patil, Ajit A."
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Antiretroviral resistance following immunological monitoring in a resource-limited setting of western India: A cross-sectional study
Published in PloS one (01-08-2017)“…The free antiretroviral therapy (ART) program in India still relies on the clinico-immunological monitoring for diagnosis of treatment failure. As the…”
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Optimization of supercritical fluid extraction and HPLC identification of wedelolactone from Wedelia calendulacea by orthogonal array design
Published in Journal of advanced research (01-11-2014)“…The purpose of this work is to provide a complete study of the influence of operational parameters of the supercritical carbon dioxide assisted extraction (SC…”
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3
Design, Synthesis and Evaluation of Antiinflammatory, Analgesic and Ulcerogenicity studies of Novel S-Substituted phenacyl-1,3,4-oxadiazole-2-thiol and Schiff bases of Diclofenac acid as Nonulcerogenic Derivatives
Published in Bioorganic & medicinal chemistry (15-02-2008)“…Diclofenac sodium is being used for its anti-inflammatory actions since 28 years, but as all the NSAIDs are suffering from the deadlier GI toxicities,…”
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4
Partial pol Sequences from Drug Naive HIV-2 Infected Individuals from Maharashtra, India
Published in AIDS research and human retroviruses (01-05-2019)“…HIV-2 is important due to its unique challenges in diagnosis, treatment, and drug resistance. The data on Indian HIV-2 gene as well as resistance to…”
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Design, Synthesis and Pharmacological Screening of Novel Antihypertensive Agents Using Hybrid Approach
Published in Bioorganic & medicinal chemistry (2009)“…Eight derivatives of general formula 2-(2-(4-(3-((5-substituted…”
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Short Communication: Limited HIV Pretreatment Drug Resistance Among Adults Attending Free Antiretroviral Therapy Clinic of Pune, India
Published in AIDS research and human retroviruses (01-04-2016)“…In India, the roll out of the free antiretroviral therapy (ART) program completed a decade of its initiation in 2014. The success of first-line ART is…”
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Supercritical CO2 Assisted Extraction and LC-MS Identification of Picroside I and Picroside II from Picrorhiza kurroa
Published in Phytochemical analysis (01-02-2013)“…ABSTRACT Introduction Picroside I and picroside II have been studied intensively because of their pharmacological actions and clinical applications. Numerous…”
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Optimization of process variables for phyllanthin extraction from Phyllanthus amarus leaves by supercritical fluid using a Box-Behnken experimental design followed by HPLC identification
Published in Acta Pharmaceutica (01-06-2013)“…The response surface methodology using the Box-Behnken design was established to describe supercritical carbon dioxide assisted extraction of phyllanthin from…”
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Design, synthesis and pharmacological screening of novel nitric oxide donors containing 1,5-diarylpyrazolin-3-one as nontoxic NSAIDs
Published in European journal of medicinal chemistry (01-11-2009)“…Various substituted 1,5-diarylpyrazol-3-one derivatives were synthesized and screened for analgesic, anti-inflammatory activities, ulcerogenic potential and…”
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High prevalence of human immunodeficiency virus type 1 drug resistance mutations in antiretroviral treatment-experienced patients from Pune, India
Published in AIDS research and human retroviruses (01-10-2007)“…We report one or more HIV resistance mutations in 81.81% of the 33 antiretroviral treatment-experienced study participants with evidence of virologic failure,…”
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Human immunodeficiency virus type 1 drug resistance mutations in peripheral blood mononuclear cell proviral DNA among antiretroviral treatment-naive and treatment-experienced patients from Pune, India
Published in AIDS research and human retroviruses (01-04-2007)“…The prevalence of HIV drug resistance (HIVDR) mutations in the HIV protease (PR) and reverse transcriptase (RT) genes was estimated from peripheral blood…”
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Optimized supercritical fluid extraction and effect of ionic liquids on picroside I and picroside II recovery from Picrorhiza scrophulariiflora rhizomes
Published in Journal of pharmaceutical investigation (01-06-2013)“…The supercritical carbon dioxide-assisted extraction (SC CO 2 E) process was optimized for extracting picroside I and picroside II from Picrorhiza…”
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13
Human immunodeficiency virus type 1 gp 41 mutations in proviral DNA among antiretroviral treatment-naive individuals from India
Published in AIDS research and human retroviruses (01-05-2009)“…The HIV-1 gp41 has been identified as an important target for the immune response, for the development of antiviral and vaccine strategies, and for…”
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Synthesis and evaluation of anti-inflammatory, analgesic, ulcerogenicity and nitric oxide-releasing studies of novel ibuprofen analogs as nonulcerogenic derivatives
Published in Medicinal chemistry research (01-09-2011)“…Since the last 41 years, Ibuprofen has been one of the most widely used Non-Steroidal Anti-Inflammatory Drug (NSAID) due to its anti-inflammatory actions. As…”
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Supercritical CO 2 Assisted Extraction and LC–MS Identification of Picroside I and Picroside II from Picrorhiza kurroa
Published in Phytochemical analysis (01-02-2013)“…The response surface methodology using 33 fractional factorial design was established to describe supercritical carbon dioxide assisted extraction of picroside…”
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Supercritical CO₂assisted extraction and LC-MS identification of picroside I and picroside II from Picrorhiza kurroa
Published in Phytochemical analysis (01-02-2013)“…Picroside I and picroside II have been studied intensively because of their pharmacological actions and clinical applications. Numerous methods have been…”
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17
Prophylactic and Therapeutic Modulation of Innate and Adaptive Immunity Against Mucosal Infection of Herpes Simplex Virus
Published in Immune network (2014)“…Herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) are the most common cause of genital ulceration in humans worldwide. Typically, HSV-1 and 2 infections via…”
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