Search Results - "Patierno, Steven"
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Toward Achieving Health Equity - ASPO's 2022 Annual Meeting March 13-15, 2022 Marriott University Park, Tucson, Arizona
Published in Cancer epidemiology, biomarkers & prevention (01-11-2021)Get full text
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Chromium genotoxicity: A double-edged sword
Published in Chemico-biological interactions (05-11-2010)“…Certain forms of hexavalent chromium [Cr(VI)] are known respiratory carcinogens that induce a broad spectrum of DNA damage. Cr(VI)-carcinogenesis may be…”
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Impact of Patient Navigation on Timely Cancer Care: The Patient Navigation Research Program
Published in JNCI : Journal of the National Cancer Institute (01-06-2014)“…Patient navigation is a promising intervention to address cancer disparities but requires a multisite controlled trial to assess its effectiveness. The Patient…”
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Prostate cancer in African American men
Published in Clinical advances in hematology & oncology (01-03-2020)Get full text
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Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer
Published in Nature communications (30-06-2017)“…Clinical challenges exist in reducing prostate cancer (PCa) disparities. The RNA splicing landscape of PCa across racial populations has not been fully…”
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Alternative RNA Splicing as a Potential Major Source of Untapped Molecular Targets in Precision Oncology and Cancer Disparities
Published in Clinical cancer research (15-05-2019)“…Studies of alternative RNA splicing (ARS) have the potential to provide an abundance of novel targets for development of new biomarkers and therapeutics in…”
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Identification and Functional Validation of Reciprocal microRNA-mRNA Pairings in African American Prostate Cancer Disparities
Published in Clinical cancer research (01-11-2015)“…African Americans (AA) exhibit higher rates of prostate cancer incidence and mortality compared with European American (EA) men. In addition to socioeconomic…”
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Dysregulation of the ESRP2-NF2-YAP/TAZ axis promotes hepatobiliary carcinogenesis in non-alcoholic fatty liver disease
Published in Journal of hepatology (01-09-2021)“…Non-alcoholic fatty liver disease (NAFLD), the hepatic correlate of the metabolic syndrome, is a major risk factor for hepatobiliary cancer (HBC). Although…”
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Differential alternative RNA splicing and transcription events between tumors from African American and White patients in The Cancer Genome Atlas
Published in Genomics (San Diego, Calif.) (01-05-2021)“…Individuals of African ancestry suffer disproportionally from higher incidence, aggressiveness, and mortality for particular cancers. This disparity likely…”
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Impact of patient navigation in eliminating economic disparities in cancer care
Published in Cancer (15-11-2015)“…BACKGROUND Patient navigation may reduce cancer disparities associated with socioeconomic status (SES) and household factors. This study examined whether these…”
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Biological Aspects of Cancer Health Disparities
Published in Annual review of medicine (27-01-2021)“…Racial and ethnic disparities span the continuum of cancer care and are driven by a complex interplay among social, psychosocial, lifestyle, environmental,…”
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Targeting CaMKK2 inhibits actin cytoskeletal assembly to suppress cancer metastasis
Published in Cancer research (Chicago, Ill.) (01-09-2023)“…Triple-negative breast cancers (TNBCs) tend to become invasive and metastatic at early stages in their development. Despite some treatment successes in early…”
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Factors associated with biomedical research participation within community‐based samples across 3 National Cancer Institute–designated cancer centers
Published in Cancer (01-03-2020)“…Background Engaging diverse populations in biomedical research, including biospecimen donation, remains a national challenge. This study examined factors…”
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Can patient navigation improve receipt of recommended breast cancer care? Evidence from the National Patient Navigation Research Program
Published in Journal of clinical oncology (01-09-2014)“…Poor and underserved women face barriers in receiving timely and appropriate breast cancer care. Patient navigators help individuals overcome these barriers,…”
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A prospective trial of abiraterone acetate plus prednisone in Black and White men with metastatic castrate‐resistant prostate cancer
Published in Cancer (15-08-2021)“…Background Retrospective analyses of randomized trials suggest that Black men with metastatic castration‐resistant prostate cancer (mCRPC) have longer survival…”
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Modifiable patient-reported factors associated with cancer-screening knowledge and participation in a community-based health assessment
Published in The American journal of surgery (01-04-2023)“…We sought to identify modifiable factors associated with cancer screening in a community-based health assessment. 24 organizations at 47 community events in…”
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Identification of Differentially Methylated Genes in Normal Prostate Tissues from African American and Caucasian Men
Published in Clinical cancer research (15-07-2010)“…Aberrant DNA methylation changes are common somatic alterations in prostate carcinogenesis. We examined the methylation status of six genes in prostate tissue…”
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Associations between RNA splicing regulatory variants of stemness‐related genes and racial disparities in susceptibility to prostate cancer
Published in International journal of cancer (15-08-2017)“…Evidence suggests that cells with a stemness phenotype play a pivotal role in oncogenesis, and prostate cells exhibiting this phenotype have been identified…”
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Helicobacter pylori testing prior to or at gastric cancer diagnosis and survival in a diverse US patient population
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2024)“…Background Gastric cancer (GC) accounts for the greatest disparity in cancer mortality between Black and White Americans. Although clinical trials have shown…”
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Single-nucleotide polymorphisms of stemness genes predicted to regulate RNA splicing, microRNA and oncogenic signaling are associated with prostate cancer survival
Published in Carcinogenesis (New York) (03-07-2018)“…We identified single-nucleotide polymorphisms (SNPs) of stemness-related genes, including CD44 (rs9666607), ABCC1 (rs35605 and rs212091) and GDF15 (rs1058587)…”
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