Search Results - "Patierno, Brendon M."

Alternative RNA Splicing as a Potential Major Source of Untapped Molecular Targets in Precision Oncology and Cancer Disparities by Robinson, Timothy J, Freedman, Jennifer A, Al Abo, Muthana, Deveaux, April E, LaCroix, Bonnie, Patierno, Brendon M, George, Daniel J, Patierno, Steven R

“…Studies of alternative RNA splicing (ARS) have the potential to provide an abundance of novel targets for development of new biomarkers and therapeutics in…”
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A prospective trial of abiraterone acetate plus prednisone in Black and White men with metastatic castrate‐resistant prostate cancer by George, Daniel J., Halabi, Susan, Heath, Elisabeth I., Sartor, A. Oliver, Sonpavde, Guru P., Das, Devika, Bitting, Rhonda L., Berry, William, Healy, Patrick, Anand, Monika, Winters, Carol, Riggan, Colleen, Kephart, Julie, Wilder, Rhonda, Shobe, Kellie, Rasmussen, Julia, Milowsky, Matthew I., Fleming, Mark T., Bearden, James, Goodman, Michael, Zhang, Tian, Harrison, Michael R., McNamara, Megan, Zhang, Dadong, LaCroix, Bonnie L., Kittles, Rick A., Patierno, Brendon M., Sibley, Alexander B., Patierno, Steven R., Owzar, Kouros, Hyslop, Terry, Freedman, Jennifer A., Armstrong, Andrew J.

“…Background Retrospective analyses of randomized trials suggest that Black men with metastatic castration‐resistant prostate cancer (mCRPC) have longer survival…”
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RNA splicing and aggregate gene expression differences in lung squamous cell carcinoma between patients of West African and European ancestry by Deveaux, April E., Allen, Tyler A., Al Abo, Muthana, Qin, Xiaodi, Zhang, Dadong, Patierno, Brendon M., Gu, Lin, Gray, Jhanelle E., Pecot, Chad V., Dressman, Holly K., McCall, Shannon J., Kittles, Rick A., Hyslop, Terry, Owzar, Kouros, Crawford, Jeffrey, Patierno, Steven R., Clarke, Jeffrey M., Freedman, Jennifer A.

“…•RNA splicing differs in lung squamous cell carcinoma by patient ancestry.•Ancestry-related differentially spliced genes have cancer…”
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Characterization of a castrate-resistant prostate cancer xenograft derived from a patient of West African ancestry by Patierno, Brendon M., Foo, Wen-Chi, Allen, Tyler, Somarelli, Jason A., Ware, Kathryn E., Gupta, Santosh, Wise, Sandra, Wise, John P., Qin, Xiaodi, Zhang, Dadong, Xu, Lingfan, Li, Yanjing, Chen, Xufeng, Inman, Brant A., McCall, Shannon J., Huang, Jiaoti, Kittles, Rick A., Owzar, Kouros, Gregory, Simon, Armstrong, Andrew J., George, Daniel J., Patierno, Steven R., Hsu, David S., Freedman, Jennifer A.

“…Background Prostate cancer is a clinically and molecularly heterogeneous disease, with highest incidence and mortality among men of African ancestry. To date,…”
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Abstract B061: Mechanistic and functional interrogation of novel ancestry-related alternatively spliced androgen receptor signal genes in prostate cancer by Onyenwoke, Rob U., Freedman, Jennifer A., Patierno, Brendon M., Eze, Cedric, Dayo, Adepeju, George, Daniel J., Patierno, Steven R.

“…Abstract The age-adjusted incidence and mortality rates for prostate cancer (PCa) among African American (AA) men are significantly higher than among white…”
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Abstract B006: Development of a novel therapeutic splice-switching oligonucleotide targeting race-related androgen receptor signaling and aggressive prostate cancer by LaCroix, Bonnie L., Patierno, Brendon M., Sullenger, Bruce A., George, Daniel J., Patierno, Steven R., Freedman, Jennifer A.

“…Abstract Background: Age-adjusted incidence and mortality rates for prostate cancer (PCa) among African American (AA) men are 1.6- and 2.4-fold greater,…”
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Abstract B064: Race-related genetic variation and response to secondary hormonal therapy in metastatic castration-resistant prostate cancer by Allen, Tyler A, Lipton, Gary, Sibley, Alexander B, Healy, Patrick, Patierno, Brendon M, Lacroix, Bonnie, Patierno, Steven R, Owzar, Kouros, Hyslop, Terry, George, Daniel J, Freedman, Jennifer A

“…Abstract Prostate cancer (PCa) is the most prevalent cancer and third leading cause of cancer death among men in the United States. PCa incidence,…”
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Abstract PR04: Development of a novel therapeutic splice-switching oligonucleotide targeting race-related androgen receptor signaling and aggressive prostate cancer by LaCroix, Bonnie L., Patierno, Brendon M., Sullenger, Bruce A., George, Daniel J., Patierno, Steven R., Freedman, Jennifer A.

“…Abstract Background: Age-adjusted incidence and mortality rates for prostate cancer (PCa) among African American (AA) men are 1.6- and 2.4-fold greater,…”
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Abstract PO-100: Ancestry-related variation in Sphingosine Kinase Type 1-Interacting Protein (SKIP) and Sphingosine Kinase 1 (SPHK1) and response to secondary hormonal therapy in metastatic castration-resistant prostate cancer by Piwarski, Sean A., Allen, Tyler A., Zhang, Dadong, Sibley, Alexander B., Healy, Patrick, Patierno, Brendon M., LaCroix, Bonnie L., Kittles, Rick A., Owzar, Kouros, Hyslop, Terry, Patierno, Steven R., George, Daniel J., Freedman, Jennifer A.

“…Abstract The number of cases and deaths from prostate cancer (PCa) is highest for African American (AA) men compared with men of other racial and ethnic…”
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Abstract A114: Characterization of a metastatic prostate cancer xenograft derived from a patient of African ancestry by Patierno, Brendon M., Glover, Wayne, Foo, Wen-Chi, Somarelli, Jason A., Ware, Kathryn E., Xu, Lingfan, Li, Yanjing, Chen, Xufeng, George, Daniel J., Kittles, Rick A., Armstrong, Andrew J., McCall, Shannon J., Huang, Jiaoti, Freedman, Jennifer A., Patierno, Steven R., Hsu, David S.

“…Abstract Background: Prostate cancer (PCa) is a clinically and molecularly heterogeneous disease, with differences in incidence and mortality among and between…”
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Abstract B18: Development of novel therapeutic splice-switching oligonucleotides against aggressive prostate cancer in men of African descent by Freedman, Jennifer A., Robinson, Timothy J., LaCroix, Bonnie, Patierno, Brendon M., George, Daniel J., Sullenger, Bruce A., Patierno, Steven R.

“…Abstract African American (AA) men exhibit a nearly 2-fold higher incidence and 3-fold higher mortality rate from prostate cancer compared to Caucasian…”
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