Search Results - "Pathology, research and practice"

Curcumin inhibits NF-kB and Wnt/β-catenin pathways in cervical cancer cells by Ghasemi, Faezeh, Shafiee, Mojtaba, Banikazemi, Zarrin, Pourhanifeh, Mohammad Hossein, Khanbabaei, Hashem, Shamshirian, Amir, Amiri Moghadam, Shirin, ArefNezhad, Reza, Sahebkar, Amirhossein, Avan, Amir, Mirzaei, Hamed

“…Curcumin is a natural non-toxic phenol which is isolated from Curcumin longa L. Mounting evidence has revealed the anticancer properties of curcumin in various…”
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Tumor microenvironment components: Allies of cancer progression by Ribeiro Franco, Pablo Igor, Rodrigues, Arthur Perillo, de Menezes, Liliana Borges, Pacheco Miguel, Marina

“…Cancer is a disease that affects millions of individuals worldwide and has a great impact on public health. Therefore, the study of tumor biology and an…”
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Recent advances and challenges of RT-PCR tests for the diagnosis of COVID-19 by Teymouri, Manoucher, Mollazadeh, Samaneh, Mortazavi, Hamed, Naderi Ghale-noie, Zari, Keyvani, Vahideh, Aghababaei, Farzaneh, Hamblin, Michael R, Abbaszadeh-Goudarzi, Ghasem, Pourghadamyari, Hossein, Hashemian, Seyed Mohammad Reza, Mirzaei, Hamed

“…Since the outbreak of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the control of virus spread has remained challenging given the…”
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The role of miRNAs in liver diseases: Potential therapeutic and clinical applications by Doghish, Ahmed S., Elballal, Mohammed S., Elazazy, Ola, Elesawy, Ahmed E., Elrebehy, Mahmoud A., Shahin, Reem K., Midan, Heba M., Sallam, Al-Aliaa M.

“…MicroRNAs (miRNAs) are a class of short, non-coding RNAs that function post-transcriptionally to regulate gene expression by binding to particular mRNA targets…”
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Unveiling the connection: Long-chain non-coding RNAs and critical signaling pathways in breast cancer by Thapa, Riya, Afzal, Obaid, Gupta, Gaurav, Bhat, Asif Ahmad, Almalki, Waleed Hassan, Alzarea, Sami I., Kazmi, Imran, Altamimi, Abdulmalik Saleh Alfawaz, Subramaniyan, Vetriselvan, Thangavelu, Lakshmi, Singh, Sachin Kumar, Dua, Kamal

“…Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways essential for cell proliferation, survival, and differentiation…”
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A study of miRNAs as cornerstone in lung cancer pathogenesis and therapeutic resistance: A focus on signaling pathways interplay by Doghish, Ahmed S., Ismail, Ahmed, Elrebehy, Mahmoud A., Elbadry, Abdullah M.M., Mahmoud, Hend H., Farouk, Salma M., Serea, Ghada A. Abu, Elghany, Rahma Ali A., El-Halwany, Kholoud K., Alsawah, Abdulrahman Omar, Dewidar, Hla I., El-Mahdy, Hesham A.

“…Lung cancer (LC) is the most common cancer-related death globally, and many efforts have been made to improve the patient care of LC patients, as well as the…”
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Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling by Hussain, Md Sadique, Afzal, Obaid, Gupta, Gaurav, Altamimi, Abdulmalik Saleh Alfawaz, Almalki, Waleed Hassan, Alzarea, Sami I., Kazmi, Imran, Fuloria, Neeraj Kumar, Sekar, Mahendran, Meenakshi, Dhanalekshmi Unnikrishnan, Thangavelu, Lakshmi, Sharma, Ajay

“…Lung cancer (LC) continues to pose a significant global medical burden, necessitating a comprehensive understanding of its molecular foundations to establish…”
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Cancer immunotherapy: Challenges and limitations by Taefehshokr, Sina, Parhizkar, Aram, Hayati, Shima, Mousapour, Morteza, Mahmoudpour, Amin, Eleid, Liliane, Rahmanpour, Dara, Fattahi, Sahand, Shabani, Hadi, Taefehshokr, Nima

“…Although cancer immunotherapy has taken center stage in mainstream oncology inducing complete and long-lasting tumor regression, only a subset of patients…”
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miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay by Doghish, Ahmed S., Ali, Mohamed A., Elyan, Salah S., Elrebehy, Mahmoud A., Mohamed, Hend H., Mansour, Reda M., Elgohary, Ayatallah, Ghanem, Aml, Faraag, Ahmed H.I., Abdelmaksoud, Nourhan M., Moustafa, Hebatallah Ahmed Mohamed

“…Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries. The persistence of infection with high-risk human papillomavirus (HPV)…”
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Hydroxycitric acid reverses tamoxifen resistance through inhibition of ATP citrate lyase by Ismail, Ahmed, Mokhlis, Hamada Ahmed, Sharaky, Marwa, Sobhy, Mohamed H., Hassanein, Sherif S., Doghish, Ahmed S., Salama, Salama A., Mariee, Amr D., Attia, Yasmin M.

“…Lipid metabolic reprogramming is involved in mediating tamoxifen (TAM) response in breast cancer cells. Published microarray data indicated that ATP citrate…”
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PI3K/Akt/mTOR signaling pathway in cancer stem cells by Karami fath, Mohsen, Ebrahimi, Menooa, Nourbakhsh, Ehsan, Zia Hazara, Ahmad, Mirzaei, Ali, Shafieyari, Saba, Salehi, Azadeh, Hoseinzadeh, Mahsa, Payandeh, Zahra, Barati, Ghasem

“…Cancer stem cells (CSCs) as a small subpopulation in tumor bulk are believed to initiate tumor formation and are responsible for the resistance to cancer…”
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miRNAs role in glioblastoma pathogenesis and targeted therapy: Signaling pathways interplay by Elshaer, Shereen Saeid, Abulsoud, Ahmed I., Fathi, Doaa, Abdelmaksoud, Nourhan M., Zaki, Mohamed Bakr, El-Mahdy, Hesham A., Ismail, Ahmed, Elsakka, Elsayed G.E., Abd-Elmawla, Mai A., Abulsoud, Logyna A., Doghish, Ahmed S.

“…High mortality and morbidity rates and variable clinical behavior are hallmarks of glioblastoma (GBM), the most common and aggressive primary malignant brain…”
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Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review by Hussain, Md Sadique, Gupta, Gaurav, Afzal, Muhammad, Alqahtani, Safar M., Samuel, Vijaya Paul, Hassan almalki, Waleed, Kazmi, Imran, Alzarea, Sami I., Saleem, Shakir, Dureja, Harish, Singh, Sachin Kumar, Dua, Kamal, Thangavelu, Lakshmi

“…Long non-coding RNAs (lncRNAs) have emerged as pivotal regulators of gene expression, contributing significantly to a diverse range of cellular processes,…”
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miRNAs as potential game-changers in bone diseases: Future medicinal and clinical uses by Doghish, Ahmed S., Elballal, Mohammed S., Elazazy, Ola, Elesawy, Ahmed E., Shahin, Reem K., Midan, Heba M., Sallam, Al-Aliaa M., Elbadry, Abdullah M.M., Mohamed, Aliaa K.I., Ishak, Nardeen W., Hassan, Kholoud Ali, Ayoub, Amira M., Shalaby, Rana E., Elrebehy, Mahmoud A.

“…MicroRNAs (miRNAs), short, highly conserved non-coding RNA, influence gene expression by sequential mechanisms such as mRNA breakdown or translational…”
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The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance – A focus on signaling pathways interplay by Ismail, Ahmed, Abulsoud, Ahmed I., Fathi, Doaa, Elshafei, Ahmed, El-Mahdy, Hesham A., Elsakka, Elsayed G.E., Aglan, Ahmed, Elkhawaga, Samy Y., Doghish, Ahmed S.

“…One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC), which is often diagnosed in its latter, deadly stages. The OC's high…”
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miRNAs as cornerstones in chronic lymphocytic leukemia pathogenesis and therapeutic resistance– An emphasis on the interaction of signaling pathways by Doghish, Ahmed S., Abulsoud, Ahmed I., Elshaer, Shereen Saeid, Abdelmaksoud, Nourhan M., Zaki, Mohamed Bakr, El-Mahdy, Hesham A., Ismail, Ahmed, Fathi, Doaa, Elsakka, Elsayed G.E.

“…Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia. Patients of advanced age are more likely to develop the condition,…”
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Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways by Doghish, Ahmed S., El-Mahdy, Hesham A., Ismail, Ahmed, Hegazy, Maghawry, Mokhtar, Mahmoud Mohamed, Elkhawaga, Samy Y., Elkady, Mohamed A., Yehia, Amr Mohamed, Elsakka, Elsayed G.E.

“…Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the Papillary thyroid cancer (PTC)(most common and follicular thyroid…”
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MALAT1: A key regulator in lung cancer pathogenesis and therapeutic targeting by Bhat, Asif Ahmad, Afzal, Obaid, Afzal, Muhammad, Gupta, Gaurav, Thapa, Riya, Ali, Haider, Hassan almalki, Waleed, Kazmi, Imran, Alzarea, Sami I., Saleem, Shakir, Samuel, Vijaya Paul, Gubbiyappa, Shiva Kumar, Subramaniyan, Vetriselvan

“…Lung cancer remains a formidable global health burden, necessitating a comprehensive understanding of the underlying molecular mechanisms driving its…”
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miRNAs as potential game-changers in head and neck cancer: Future clinical and medicinal uses by El-Mahdy, Hesham A., Mohamadin, Ahmed M., Abulsoud, Ahmed I., Khidr, Emad Gamil, El-Husseiny, Ahmed A., Ismail, Ahmed, Elsakka, Elsayed G.E., Mokhlis, Hamada Ahmed, El-Husseiny, Hussein M., Doghish, Ahmed S.

“…Head and neck cancers (HNCs) are a group of heterogeneous tumors formed most frequently from epithelial cells of the larynx, lips, oropharynx, nasopharynx, and…”
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The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy by Zaki, Mohamed Bakr, Abulsoud, Ahmed I., Elshaer, Shereen Saeid, Fathi, Doaa, Abdelmaksoud, Nourhan M., El-Mahdy, Hesham A., Ismail, Ahmed, Elsakka, Elsayed G.E., Sallam, Al-Aliaa M., Doghish, Ahmed S.

“…Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular carcinoma, has been rising worldwide in recent epidemiological research…”
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