Search Results - "Pathobiology (Basel)"

The Impact of COVID-19 Disease on Platelets and Coagulation by Wool, Geoffrey D, Miller, Jonathan L

“…Coronavirus disease 2019 (COVID-19) causes a spectrum of disease; some patients develop a severe proinflammatory state which can be associated with a unique…”
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Oral Microbiota and Cancer Development by Tuominen, Heidi, Rautava, Jaana

“…Oral microbiota are among the most diverse in the human body. More than 700 species have been identified in the mouth, and new sequencing methods are allowing…”
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Autopsy Findings in 32 Patients with COVID-19: A Single-Institution Experience by Elsoukkary, Sarah S, Mostyka, Maria, Dillard, Alicia, Berman, Diana R, Ma, Lucy X, Chadburn, Amy, Yantiss, Rhonda K, Jessurun, Jose, Seshan, Surya V, Borczuk, Alain C, Salvatore, Steven P

“…A novel coronavirus, SARS-CoV-2, was identified in Wuhan, China in late 2019. This virus rapidly spread around the world causing disease ranging from minimal…”
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Role of the Tumor Microenvironment in Breast Cancer by Soysal, Savas D, Tzankov, Alexandar, Muenst, Simone E

“…In recent years, it has been shown that breast cancer consists not only of neoplastic cells, but also of significant alterations in the surrounding stroma or…”
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Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion by Menter, Thomas, Mertz, Kirsten Diana, Jiang, Sizun, Chen, Han, Monod, Cécile, Tzankov, Alexandar, Waldvogel, Salome, Schulzke, Sven M, Hösli, Irene, Bruder, Elisabeth

“…Since the outbreak of coronavirus disease 2019 (COVID-19), there has been a debate whether pregnant women are at a specific risk for COVID-19 and whether it…”
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Protocadherin B9 Is Associated with Human Esophageal Squamous Cell Carcinoma Progression by Fujiki, Yuto, Ishikawa, Akira, Akabane, Shintaro, Mukai, Shoichiro, Maruyama, Ryota, Yamamoto, Yuji, Kido, Aya, Katsuya, Narutaka, Taniyama, Daiki, Sentani, Kazuhiro, Oue, Naohide, Yasui, Wataru

“…Esophageal cancer is the sixth leading cause of cancer-related death worldwide. However, molecular targeted therapy and novel therapeutic targets are needed…”
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Exploring the Expression of Adenosine Pathway-Related Markers CD73 and CD39 in Colorectal and Pancreatic Carcinomas Characterized by Multiplex Immunofluorescence: A Pilot Study by Lima, Cibelle Freitas, Tamegnon, Auriole, Rodriguez, Saxon, Maru, Dipen, Martin, Philip L, Cooper, Zachary A, Rodriguez-Canales, Jaime, Parra, Edwin Roger

“…Generating high levels of immunosuppressive adenosine (ADO) in the tumor microenvironment contributes to cancer immune evasion. CD39 and CD73 hydrolyze…”
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Discrepancies in Hormone Receptor and HER2 Expression between Malignant Serous Effusions and Paired Tissues from Primary or Recurrent Breast Cancers by Nikas, Ilias P, Lim, Sojung, Im, Seock-Ah, Lee, Kyung-Hun, Lee, Dae-Won, Lee, Hyebin, Ryu, Han Suk

“…Immunohistochemistry (IHC) for the estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) biomarkers has…”
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Current Status of Whole-Slide Imaging in Education by Saco, Adela, Bombi, Jose Antoni, Garcia, Adriana, Ramírez, Jose, Ordi, Jaume

“…Conventional light microscopy (CLM) has classically been the basic tool to teach histology and pathology. In recent years, whole-slide imaging (WSI), which…”
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Characterization of the Immune Microenvironment in Inflammatory Breast Cancer Using Multiplex Immunofluorescence by Badr, Nahla M, McMurray, Jack L, Danial, Irini, Hayward, Steven, Asaad, Nancy Y, Abd El-Wahed, Moshira M, Abdou, Asmaa G, Serag El-Dien, Marwa M, Sharma, Nisha, Horimoto, Yoshiya, Sircar, Tapan, Vidya, Raghavan, Hoar, Fiona, Rea, Daniel, Jones, J Louise, Stevens, Andrea, Spooner, David, Merard, Reena, Lewis, Paul, Hunter, Kelly John, Berditchevski, Fedor, Shaaban, Abeer M

“…Inflammatory breast cancer (IBC) is an aggressive form of breast cancer with a poorly characterized immune microenvironment. We used a five-colour multiplex…”
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Molecular Characterization and Genetic Subclassification Comparison of Diffuse Large B-Cell Lymphoma: Real-Life Experience with 74 Cases by Ivanova, Vanesa-Sindi, Vela, Visar, Dirnhofer, Stefan, Dobbie, Michael, Stenner, Frank, Knoblich, Jan, Tzankov, Alexandar, Menter, Thomas

“…Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous entity. Lately, several algorithms achieving therapeutically and prognostically relevant DLBCL…”
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Prognostic Significance of Intratumoral and Peritumoral Budding in Distal Extrahepatic Bile Duct Carcinoma by Jun, Sun-Young, Hong, Seung-Mo, An, Soyeon

“…Although tumor budding (TB) has been recognized as a representative adverse prognosticator in gastrointestinal malignancies, it is not well elucidated in…”
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Performance of Immunohistochemical and Molecular Methods in Detecting Microsatellite Instability in Gastric Cancer: A Multicenter Study by Sousa Marques, Diogo, Gullo, Irene, Mascarenhas-Lemos, Luís, Silva, João Ricardo, Neto do Nascimento, Catarina, Pontes, Patrícia, Pinho, Lídia, Cirnes, Luis, Wen, Xiaogang, Cravo, Marília, Carneiro, Fátima

“…Microsatellite instability (MSI) is an important prognostic molecular biomarker for gastric cancer (GC). MSI status may be detected by immunohistochemistry…”
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High Inner Centromere Protein Expression Correlates with Aggressive Features and Predicts Poor Prognosis in Patients with Invasive Breast Cancer by Ibrahim, Asmaa, Miligy, Islam M, Toss, Michael S, Green, Andrew R, Rakha, Emad A

“…Inner centromere protein (INCENP) is a member of the chromosomal passenger complex and plays a key role in mitosis and cell proliferation. This study aimed to…”
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The Use of Pan-Tropomyosin Receptor Kinase Immunohistochemistry as a Screening Tool for the Detection of Neurotrophic Tropomyosin-Related Kinase Fusions: Real-World Data from a National Multicentric Retrospective Study by Van Bockstal, Mieke R, Beniuga, Gabriela, Craciun, Ligia, Creytens, David, Dedeurwaerdere, Franceska, Delvenne, Philippe, Demetter, Pieter, De Wiest, Bart, Dewinne, Koen, Habran, Lionel, Pauwels, Patrick, Theate, Ivan, Vander Borght, Sara, Van Der Steen, Kris, Weynand, Birgit

“…The neurotrophic tropomyosin-related kinase (NTRK) genes encode the tropomyosin receptor kinases (TRKs). Patients with solid tumors harboring an oncogenic NTRK…”
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ANXA10 Expression Is Inversely Associated with Tumor Stage, Grade, and TP53 Expression in Upper and Lower Urothelial Carcinoma by Kobayashi, Go, Hayashi, Tetsutaro, Sentani, Kazuhiro, Ikeda, Kenichiro, Babasaki, Takashi, Shigematsu, Yoshinori, Sekino, Yohei, Uraoka, Naohiro, Teishima, Jun, Matsubara, Akio, Hinata, Nobuyuki, Oue, Naohide

“…Urothelial carcinoma (UC) is a common type of malignant disease, but little is known about the diagnostic and prognostic markers of upper urinary tract…”
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IQ Motif Containing GTPase-Activating Protein 3 Is Associated with Cancer Stemness and Survival in Pancreatic Ductal Adenocarcinoma by Kido, Aya, Ishikawa, Akira, Fukui, Takafumi, Katsuya, Narutaka, Kuraoka, Kazuya, Sentani, Kazuhiro, Tazuma, Sho, Sudo, Takeshi, Serikawa, Masahiro, Oka, Shiro, Oue, Naohide, Yasui, Wataru

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal types of malignancy, with poor prognosis and rising incidence. IQ motif containing…”
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Relative Telomere Length in Cervical Exfoliated Cells among Women with High-Risk Human Papillomavirus by Al-Awadhi, Rana, Alwehaidah, Materah Salem, AlRoomy, Moody, Kapila, Kusum

“…This study investigates and compares the relative telomere length (RTL) outcome of high-risk (hr) human papillomavirus (HPV)-infected normal, low-grade…”
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Challenges and Clinical Relevance of Modern Breast Pathology Reporting: Your Questions Answered by Deb, Rahul, Laokulrath, Natthawadee, Chagla, Leena, Tan, Puay Hoon

“…Breast pathology reporting, especially for breast cancer, has evolved through the years, from terse succinct diagnostic conclusions with scant histological…”
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Gastric Polyps in Familial Adenomatous Polyposis Portuguese Patients: The First Western Cohort with Asian Features by Baptista, Diana, Fernandes, Marco, Garrido, Monica, Sousa, Fabiana, Morais, Rui, Garcia-Pelaez, José, Silva, Roberto, Leitão, Dina, Baptista, Manuela, Barbosa, José, Carneiro, Fátima, Gullo, Irene

“…Chronic atrophic gastritis may contribute to gastric polyps (GP) phenotype in familial adenomatous polyposis (FAP). Considering the high prevalence of…”
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