Search Results - "Pathak, Khyatiben V"

Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders by Winstone, Joanna K, Pathak, Khyatiben V, Winslow, Wendy, Piras, Ignazio S, White, Jennifer, Sharma, Ritin, Huentelman, Matthew J, Pirrotte, Patrick, Velazquez, Ramon

“…Herbicides are environmental contaminants that have gained much attention due to the potential hazards they pose to human health. Glyphosate, the active…”
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Urinary glyphosate concentration in pregnant women in relation to length of gestation by Lesseur, Corina, Pathak, Khyatiben V., Pirrotte, Patrick, Martinez, Melissa N., Ferguson, Kelly K., Barrett, Emily S., Nguyen, Ruby H.N., Sathyanarayana, Sheela, Mandrioli, Daniele, Swan, Shanna H., Chen, Jia

“…Human exposure to glyphosate-based herbicides (GBH) is increasing rapidly worldwide. Most existing studies on health effects of glyphosate have focused on…”
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Correction: Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNFα: implications for neurodegenerative disorders by Winstone, Joanna K, Pathak, Khyatiben V, Winslow, Wendy, Piras, Ignazio S, White, Jennifer, Sharma, Ritin, Huentelman, Matthew J, Pirrotte, Patrick, Velazquez, Ramon

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Acquired miR-142 deficit in leukemic stem cells suffices to drive chronic myeloid leukemia into blast crisis by Zhang, Bin, Zhao, Dandan, Chen, Fang, Frankhouser, David, Wang, Huafeng, Pathak, Khyatiben V., Dong, Lei, Torres, Anakaren, Garcia-Mansfield, Krystine, Zhang, Yi, Hoang, Dinh Hoa, Chen, Min-Hsuan, Tao, Shu, Cho, Hyejin, Liang, Yong, Perrotti, Danilo, Branciamore, Sergio, Rockne, Russell, Wu, Xiwei, Ghoda, Lucy, Li, Ling, Jin, Jie, Chen, Jianjun, Yu, Jianhua, Caligiuri, Michael A., Kuo, Ya-Huei, Boldin, Mark, Su, Rui, Swiderski, Piotr, Kortylewski, Marcin, Pirrotte, Patrick, Nguyen, Le Xuan Truong, Marcucci, Guido

“…The mechanisms underlying the transformation of chronic myeloid leukemia (CML) from chronic phase (CP) to blast crisis (BC) are not fully elucidated. Here, we…”
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Shotgun proteomics coupled to nanoparticle-based biomarker enrichment reveals a novel panel of extracellular matrix proteins as candidate serum protein biomarkers for early-stage breast cancer detection by Fredolini, Claudia, Pathak, Khyatiben V, Paris, Luisa, Chapple, Kristina M, Tsantilas, Kristine A, Rosenow, Matthew, Tegeler, Tony J, Garcia-Mansfield, Krystine, Tamburro, Davide, Zhou, Weidong, Russo, Paul, Massarut, Samuele, Facchiano, Francesco, Belluco, Claudio, De Maria, Ruggero, Garaci, Enrico, Liotta, Lance, Petricoin, Emanuel F, Pirrotte, Patrick

“…The lack of specificity and high degree of false positive and false negative rates when using mammographic screening for detecting early-stage breast cancer is…”
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Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies by Liefwalker, Daniel F, Ryan, Meital, Wang, Zhichao, Pathak, Khyatiben V, Plaisier, Seema, Shah, Vidhi, Babra, Bobby, Dewson, Gabrielle S, Lai, Ian K, Mosley, Adriane R, Fueger, Patrick T, Casey, Stephanie C, Jiang, Lei, Pirrotte, Patrick, Swaminathan, Srividya, Sears, Rosalie C

“…Metabolic reprogramming is a central feature in many cancer subtypes and a hallmark of cancer. Many therapeutic strategies attempt to exploit this feature,…”
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Maternal urinary levels of glyphosate during pregnancy and anogenital distance in newborns in a US multicenter pregnancy cohort by Lesseur, Corina, Pirrotte, Patrick, Pathak, Khyatiben V., Manservisi, Fabiana, Mandrioli, Daniele, Belpoggi, Fiorella, Panzacchi, Simona, Li, Qian, Barrett, Emily S., Nguyen, Ruby H.N., Sathyanarayana, Sheela, Swan, Shanna H., Chen, Jia

“…Human exposure to glyphosate has become ubiquitous because of its increasing agricultural use. Recent studies suggest endocrine disrupting effects of…”
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Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women by Lucia, Rachel M, Huang, Wei-Lin, Pathak, Khyatiben V, McGilvrey, Marissa, David-Dirgo, Victoria, Alvarez, Andrea, Goodman, Deborah, Masunaka, Irene, Odegaard, Andrew O, Ziogas, Argyrios, Pirrotte, Patrick, Norden-Krichmar, Trina M, Park, Hannah Lui

“…Glyphosate is the most commonly used herbicide in the world and is purported to have a variety of health effects, including endocrine disruption and an…”
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Immunometabolic Adaptation of CD19-Targeted CAR T Cells in the Central Nervous System Microenvironment of Patients Promotes Memory Development by Goldberg, Lior, Haas, Eric R, Urak, Ryan, Vyas, Vibhuti, Pathak, Khyatiben V, Garcia-Mansfield, Krystine, Pirrotte, Patrick, Singhal, Jyotsana, Figarola, James L, Aldoss, Ibrahim, Forman, Stephen J, Wang, Xiuli

“…Metabolic reprogramming is a hallmark of T-cell activation, and metabolic fitness is fundamental for T-cell-mediated antitumor immunity. Insights into the…”
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Methemoglobin Formation and Characterization of Hemoglobin Adducts of Carcinogenic Aromatic Amines and Heterocyclic Aromatic Amines by Pathak, Khyatiben V, Chiu, Ting-Lan, Amin, Elizabeth Ambrose, Turesky, Robert J

“…Arylamines (AAs) and heterocyclic aromatic amines (HAAs) are structurally related carcinogens formed during the combustion of tobacco or cooking of meat. They…”
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Molecular Profiling of Innate Immune Response Mechanisms in Ventilator-associated Pneumonia by Pathak, Khyatiben V., McGilvrey, Marissa I., Hu, Charles K., Garcia-Mansfield, Krystine, Lewandoski, Karen, Eftekhari, Zahra, Yuan, Yate-Ching, Zenhausern, Frederic, Menashi, Emmanuel, Pirrotte, Patrick

“…Unlike bronchoalveolar lavages (BAL), the molecular composition of more readily accessible endotracheal aspirates (ETA) has been poorly studied in the context…”
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Disruption of dNTP homeostasis by ribonucleotide reductase hyperactivation overcomes AML differentiation blockade by Wang, Hanying, He, Xin, Zhang, Lei, Dong, Haojie, Huang, Feiteng, Xian, Jie, Li, Min, Chen, Wei, Lu, Xiyuan, Pathak, Khyatiben V, Huang, Wenfeng, Li, Zheng, Zhang, Lianjun, Nguyen, Le Xuan Truong, Yang, Lu, Feng, Lifeng, Gordon, David J, Zhang, Jing, Pirrotte, Patrick, Chen, Chun-Wei, Salhotra, Amandeep, Kuo, Ya-Huei, Horne, David, Marcucci, Guido, Sykes, David B, Tiziani, Stefano, Jin, Hongchuan, Wang, Xian, Li, Ling

“…Differentiation blockade is a hallmark of acute myeloid leukemia (AML). A strategy to overcome such a blockade is a promising approach against the disease. The…”
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2-Amino-9H-pyrido[2,3-b]indole (AαC) Adducts and Thiol Oxidation of Serum Albumin as Potential Biomarkers of Tobacco Smoke by Pathak, Khyatiben V., Bellamri, Medjda, Wang, Yi, Langouët, Sophie, Turesky, Robert J.

“…2-Amino-9H-pyrido[2,3-b]indole (AαC) is a carcinogenic heterocyclic aromatic amine formed during the combustion of tobacco. AαC undergoes bioactivation to form…”
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Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type by Ji, Jennifer X, Cochrane, Dawn R, Tessier-Cloutier, Basile, Chen, Shary Yutin, Ho, Germain, Pathak, Khyatiben V, Alcazar, Isabel N, Farnell, David, Leung, Samuel, Cheng, Angela, Chow, Christine, Colborne, Shane, Negri, Gian Luca, Kommoss, Friedrich, Karnezis, Anthony, Morin, Gregg B, McAlpine, Jessica N, Gilks, C Blake, Weissman, Bernard E, Trent, Jeffrey M, Hoang, Lynn, Pirrotte, Patrick, Wang, Yemin, Huntsman, David G

“…Many rare ovarian cancer subtypes, such as small-cell carcinoma of the ovary, hypercalcemic type (SCCOHT), have poor prognosis due to their aggressive nature…”
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Urinary glyphosate and AMPA levels in a cross-sectional study of postmenopausal women: Associations with organic eating behavior and dietary intake by Lucia, Rachel M., Liao, Xiyue, Huang, Wei-Lin, Forman, Danielle, Kim, Alexis, Ziogas, Argyrios, Norden-Krichmar, Trina M., Goodman, Deborah, Alvarez, Andrea, Masunaka, Irene, Pathak, Khyatiben V., McGilvrey, Marissa, Hegde, Apurva M., Pirrotte, Patrick, Park, Hannah Lui

“…Animal and epidemiologic studies suggest that there may be adverse health effects from exposure to glyphosate, the most highly used pesticide in the world, and…”
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Exploiting the Metabolic Vulnerability of Leukemic Stem Cells (LSCs) in Inv(16) Acute Myeloid Leukemia (AML) with the Combination of Miristen, a Mir-126 Inhibitor, and Venetoclax by Zhang, Lianjun, Hoang, Dinh Hoa, Kang, Hyunjun, Chen, Ying-Chieh, Fu, Yu-Hsuan, Pathak, Khyatiben V., Valerio, Melissa, Chen, Fang, Estrella, Katrina, Buettner, Ralf, Zhang, Bin, Pirrotte, Patrick, Marcucci, Guido, Kuo, Ya-Huei, Nguyen, Le Xuan Truong

“…AML with inv(16)(p13q22) expresses the leukemogenic fusion gene CBFB-MYH11 and upregulates microRNA (miR)-126 that supports homeostasis, quiescence, and…”
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In Vivo Antileukemic Activity of Ost-01 in Acute Myeloid Leukemia (AML): A Novel Natural Product (NP) from Baccharis Coridifolia by Kang, Hyunjun, Hoang, Dinh Hoa, Valerio, Melissa, Pathak, Khyatiben V., Zhang, Lianjun, Buettner, Ralf, Chen, Fang, Estrella, Katrina, Graff, William, Kuo, Ya-Huei, Zhang, Bin, Pirrotte, Patrick, Nguyen, Le Xuan Truong, Marcucci, Guido

“…Baccharis is the largest genus in the Asteraceae and has been long used by phytomedicine practitioners in South America to treat a variety of medical…”
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Correction: Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNF[alpha]: implications for neurodegenerative disorders by Winstone, Joanna K, Pathak, Khyatiben V, Winslow, Wendy, Piras, Ignazio S, White, Jennifer, Sharma, Ritin, Huentelman, Matthew J, Pirrotte, Patrick, Velazquez, Ramon

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Acquired microRNA-142 Deficit Drives Escape Mechanisms of Anti-Leukemic Surveillance during Blast Crisis Transformation of Chronic Myeloid Leukemia (CML) by Chen, Fang, Zhao, Dandan, Zhang, Yi, Xu, Yongfang, Chen, Min-Hsuan, Pathak, Khyatiben V., Liang, Yong, Wang, Wei-Le, Estrella, Katrina, Wu, Xiwei, Ghoda, Lucy Y., Kuo, Ya-Huei, Ali, Haris, Yu, Jianhua, Caligiuri, Michael A, Boldin, Mark, Swiderski, Piotr, Kortylewski, Marcin, Pirrotte, Patrick, Nguyen, Le Xuan Truong, Marcucci, Guido, Zhang, Bin

“…CML may evolve from a chronic phase (CP) into blast crisis (BC), but the underlying mechanisms of the transformation remain to be fully elucidated. We reported…”
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Glyphosate infiltrates the brain and increases pro-inflammatory cytokine TNF[alpha]: implications for neurodegenerative disorders by Winstone, Joanna K, Pathak, Khyatiben V, Winslow, Wendy, Piras, Ignazio S, White, Jennifer, Sharma, Ritin, Huentelman, Matthew J, Pirrotte, Patrick, Velazquez, Ramon

“…Background Herbicides are environmental contaminants that have gained much attention due to the potential hazards they pose to human health. Glyphosate, the…”
Get full text