Search Results - "Pathak, K."
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A Review of Small Molecule Inhibitors and Functional Probes of Human Cathepsin L
Published in Molecules (Basel, Switzerland) (06-02-2020)“…Human cathepsin L belongs to the cathepsin family of proteolytic enzymes with primarily an endopeptidase activity. Although its primary functions were…”
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2
Detouring of cisplatin to access mitochondrial genome for overcoming resistance
Published in Proceedings of the National Academy of Sciences - PNAS (22-07-2014)“…Chemoresistance of cisplatin therapy is related to extensive repair of cisplatin-modified DNA in the nucleus by the nucleotide excision repair (NER)…”
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3
Therapeutic and cosmeceutical potential of ethosomes: An overview
Published in Journal of advanced pharmaceutical technology and research (01-07-2010)“…The main disadvantage of transdermal drug delivery is the poor penetration of most compounds into the human skin. The main barrier of the skin is located…”
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4
HIV-1 uncoats in the nucleus near sites of integration
Published in Proceedings of the National Academy of Sciences - PNAS (10-03-2020)“…HIV-1 capsid core disassembly (uncoating) must occur before integration of viral genomic DNA into the host chromosomes, yet remarkably, the timing and cellular…”
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5
The Prodrug Platin-A: Simultaneous Release of Cisplatin and Aspirin
Published in Angewandte Chemie International Edition (10-02-2014)“…Cancer‐associated inflammation induces tumor progression to the metastatic stage, thus indicating that a chemo‐anti‐inflammatory strategy is of interest for…”
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6
Ultrasmooth organic–inorganic perovskite thin-film formation and crystallization for efficient planar heterojunction solar cells
Published in Nature communications (30-01-2015)“…To date, there have been a plethora of reports on different means to fabricate organic–inorganic metal halide perovskite thin films; however, the inorganic…”
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7
Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes
Published in PLoS pathogens (21-08-2017)“…The dynamics and regulation of HIV-1 nuclear import and its intranuclear movements after import have not been studied. To elucidate these essential HIV-1…”
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8
Identification of lead vacancy defects in lead halide perovskites
Published in Nature communications (22-09-2021)“…Perovskite photovoltaics advance rapidly, but questions remain regarding point defects: while experiments have detected the presence of electrically active…”
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9
Cerium: An Unlikely Replacement of Dysprosium in High Performance Nd-Fe-B Permanent Magnets
Published in Advanced materials (Weinheim) (24-04-2015)“…Replacement of Dy and substitution of Nd in NdFeB‐based permanent magnets by Ce, the most abundant and lowest cost rare earth element, is important because Dy…”
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10
PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study
Published in Europace (London, England) (01-12-2018)“…Atrial fibrillation (AF) is a progressive disease. Obesity is associated with progression of AF. This study evaluates the impact of weight and risk factor…”
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Non-hysteretic first-order phase transition with large latent heat and giant low-field magnetocaloric effect
Published in Nature communications (26-07-2018)“…First-order magnetic transitions (FOMTs) with a large discontinuity in magnetization are highly sought in the development of advanced functional magnetic…”
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12
A Nanoparticle Cocktail: Temporal Release of Predefined Drug Combinations
Published in Journal of the American Chemical Society (08-07-2015)“…A single magic bullet is not enough for treatment of metastatic cancers. However, administration of a combination of free drugs can be extremely challenging…”
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13
Performance and Stability Enhancement of Dye-Sensitized and Perovskite Solar Cells by Al Doping of TiO2
Published in Advanced functional materials (01-10-2014)“…Reversible photo‐induced performance deterioration is observed in mesoporous TiO2‐containing devices in an inert environment. This phenomenon is correlated…”
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14
Sensitivity Enhancement of a Concave Shaped Optical Fiber Refractive Index Sensor Covered with Multiple Au Nanowires
Published in Sensors (Basel, Switzerland) (27-09-2019)“…In the present paper, a new kind of concave shaped refractive index sensor (CSRIS) exploiting localized surface plasmon resonance (LSPR) is proposed and…”
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15
Porous carriers for controlled/modulated drug delivery
Published in Indian journal of pharmaceutical sciences (01-11-2009)“…Considerable research efforts have been directed in recent years towards the development of porous carriers as controlled drug delivery matrices because of…”
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16
Aggressive Risk Factor Reduction Study for Atrial Fibrillation and Implications for the Outcome of Ablation
Published in Journal of the American College of Cardiology (02-12-2014)“…Abstract Background The long-term outcome of atrial fibrillation (AF) ablation demonstrates attrition. This outcome may be due to failure to attenuate the…”
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17
Excellent mechanical properties of long multiwalled carbon nanotube bridged Kevlar fabric
Published in Carbon (New York) (01-10-2018)“…The major causes of failure of Kevlar reinforced composites are inter-yarn slippage and poor adhesion with polymer. Herein, long length multiwalled carbon…”
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18
Camel Milk: An Important Natural Adjuvant
Published in Agricultural research (India : Online) (01-12-2017)“…One humped camel ( Camelus dromedarius ) breeds, indigenous to India, have been shown to have good genetic potential to produce milk. Camel milk not only is…”
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A Prodrug of Two Approved Drugs, Cisplatin and Chlorambucil, for Chemo War Against Cancer
Published in Molecular cancer therapeutics (01-04-2017)“…Cancer cells maintain normal mitochondrial glutathione as one of the defense mechanisms to inhibit mitochondrial membrane polarization and hence apoptosis. A…”
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20
Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them All
Published in Journal of molecular biology (20-03-2014)“…Several members of the APOBEC3 family of cellular restriction factors provide intrinsic immunity to the host against viral infection. Specifically, APOBEC3DE,…”
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