Search Results - "Paterson, H.F."

Ras recruits Raf‐1 to the plasma membrane for activation by tyrosine phosphorylation by Marais, R., Light, Y., Paterson, H.F., Marshall, C.J.

“…A central feature of signal transduction downstream of both receptor and oncogenic tyrosine kinases is the Ras‐dependent activation of a protein kinase cascade…”
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A single autophosphorylation site confers oncogenicity to the Neu/ErbB‐2 receptor and enables coupling to the MAP kinase pathway by Ben‐Levy, R., Paterson, H.F., Marshall, C.J., Yarden, Y.

“…The transforming potential of the Neu/ErbB‐2 receptor tyrosine kinase undergoes inactivation by deletion of the non‐catalytic C‐terminal tail, which contains…”
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rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo by Ridley, A.J., Self, A.J., Kasmi, F., Paterson, H.F., Hall, A., Marshall, C.J., Ellis, C.

“…rho family GTPases link extracellular signals to changes in the organization of cytoskeletal actin. Serum stimulation of quiescent Swiss 3T3 fibroblasts leads…”
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