Search Results - "Patente, Thiago Andrade"
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Macrophage inflammatory state in Type 1 diabetes: triggered by NLRP3/iNOS pathway and attenuated by docosahexaenoic acid
Published in Clinical science (1979) (15-01-2021)“…Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease characterized by insulin-producing pancreatic β-cell destruction and hyperglycemia. While…”
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Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis
Published in Frontiers in immunology (20-01-2022)“…Short-chain fatty acids (SCFAs) are metabolites produced mainly by the gut microbiota with a known role in immune regulation. Acetate, the major SCFA, is…”
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Gain-of-function variants in NLRP1 protect against the development of diabetic kidney disease: NLRP1 inflammasome role in metabolic stress sensing?
Published in Clinical immunology (Orlando, Fla.) (01-02-2018)“…Although inflammasome plays a well-known role in animal models of renal injury, limited studies in humans are available, and its participation in diabetic…”
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High-mannose glycans from Schistosoma mansoni eggs are important for priming of Th2 responses via Dectin-2 and prostaglandin E2
Published in Frontiers in immunology (2024)“…The parasitic helminth is a potent inducer of type 2 immune responses by stimulating dendritic cells (DCs) to prime T helper 2 (Th2) responses. We previously…”
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Frequency determination of breast tumor-reactive CD4 and CD8 T cells in humans: unveiling the antitumor immune response
Published in Oncoimmunology (03-08-2019)“…As cancer immunotherapy gains importance, the determination of a patient's ability to react to his/her tumor is unquestionably relevant. Though the presence of…”
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Abstract 2800: Oral cancer cell-derived extracellular vesicles can modulate an immunosuppressive microenvironment through M2 phenotype polarization
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Oral squamous cell carcinoma (OSCC) is the most prevalent malignant tumor among head and neck cancers, with 300,000 new cases and 145,000 deaths…”
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Allelic variations in genes belonging to glutathione system increase proliferative retinopathy risk in type 1 diabetes individuals
Published in Gene (30-06-2019)“…Given the participation of oxidative stress in the pathogenesis of diabetic complications, we evaluated, in type 1 diabetes (T1D) individuals, the association…”
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