Search Results - "Patel‐Murray, Natasha"

Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARAGON-HF Proteomic Substudy by Patel-Murray, Natasha L, Zhang, Luqing, Claggett, Brian L, Xu, Dongchu, Serrano-Fernandez, Pablo, Healey, Margaret, Wandel, Simon, Chen, Chien-Wei, Jacob, Jaison, Xu, Huilei, Turner, Gordon M, Chutkow, William, Yates, Denise P, O'Donnell, Christopher J, Prescott, Margaret F, Lefkowitz, Martin, Gimpelewicz, Claudio R, Beste, Michael T, Zhao, Faye, Gou, Liangke, Desai, Akshay S, Jhund, Pardeep S, Packer, Milton, Pfeffer, Marc A, Redfield, Margaret M, Rouleau, Jean L, Zannad, Faiez, Zile, Michael R, McMurray, John J V, Mendelson, Michael M, Solomon, Scott D, Cunningham, Jonathan W

“…Prognostic markers and biological pathways linked to detrimental clinical outcomes in heart failure with preserved ejection fraction (HFpEF) remain…”
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Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells by Milani, Pamela, Escalante-Chong, Renan, Shelley, Brandon C., Patel-Murray, Natasha L., Xin, Xiaofeng, Adam, Miriam, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N., Fraenkel, Ernest

“…In recent years, the assay for transposase-accessible chromatin using sequencing (ATAC-Seq) has become a fundamental tool of epigenomic research. However, it…”
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A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules by Patel-Murray, Natasha L., Adam, Miriam, Huynh, Nhan, Wassie, Brook T., Milani, Pamela, Fraenkel, Ernest

“…High-throughput screening and gene signature analyses frequently identify lead therapeutic compounds with unknown modes of action (MoAs), and the resulting…”
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Aptamer Proteomics for Biomarker Discovery in Heart Failure With Reduced Ejection Fraction by Zhang, Luqing, Cunningham, Jonathan W., Claggett, Brian L., Jacob, Jaison, Mendelson, Michael M., Serrano-Fernandez, Pablo, Kaiser, Sergio, Yates, Denise P., Healey, Margaret, Chen, Chien-Wei, Turner, Gordon M., Patel-Murray, Natasha L., Zhao, Faye, Beste, Michael T., Laramie, Jason M., Abraham, William T., Jhund, Pardeep S., Kober, Lars, Packer, Milton, Rouleau, Jean, Zile, Michael R., Prescott, Margaret F., Lefkowitz, Martin, McMurray, John J.V., Solomon, Scott D., Chutkow, William

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Machine Learning for Proteomic Risk Scores in Heart Failure by Xu, Dongchu, Cunningham, Jonathan, Marti-Castellote, Pablo-Miki, Zhang, Luqing, Patel-Murray, Natasha L, Prescott, Margaret F, Chutkow, William, Mendelson, Michael M, Solomon, Scott D, Claggett, Brian L

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Clinical characteristics of heart failure with reduced ejection fraction patients with rare pathogenic variants in dilated cardiomyopathy‐associated genes: A subgroup analysis of the PARADIGM‐HF trial by Barat, Ana, Chen, Chien‐Wei, Patel‐Murray, Natasha, McMurray, John J.V., Packer, Milton, Solomon, Scott D., Desai, Akshay S., Rouleau, Jean L., Zile, Michael R., Attari, Zenab, Zhang, Cong, Xu, Huilei, Hartman, Nicole, Hon, Claudia, Healey, Margaret, Chutkow, William, O'Donnell, Christopher J., Jacob, Jaison, Lefkowitz, Marty, Mendelson, Michael M., Wandel, Simon, Yates, Denise, Gimpelewicz, Claudio

“…Aims To evaluate the prevalence of pathogenic variants in genes associated with dilated cardiomyopathy (DCM) in a clinical trial population with heart failure…”
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Abstract 13828: Aptamer Proteomics for Biomarker Discovery in Heart Failure With Preserved Ejection Fraction: The PARADIGM-HF Proteomic Sub-Study by Patel-Murray, Natasha, Zhang, Luqing, Claggett, Brian, Xu, Dongchu, Serrano-Fernandez, Pablo, Wandel, Simon, Xu, Huilei, Healey, Margaret, Turner, Gordon, Chen, Chien-Wei, Zhao, Faye, CHUTKOW, WILLIAM A, Yates, Denise, ODonnell, Christopher, Prescott, Margaret, Lefkowitz, Martin P, Gimpelewicz, Claudio R, Beste, Michael, Gou, Liangke, Desai, Akshay S, Jhund, Pardeep S, Packer, Milton, Pfeffer, Marc A, Redfield, Margaret M, Rouleau, Jean L, ZANNAD, Faiez, Zile, Michael R, McMurray, John J, Mendelson, Michael, Solomon, Scott D, Cunningham, Jonathan

“…Abstract only Introduction: Prognostic markers and biological pathways linked to detrimental clinical outcomes in heart failure with preserved ejection…”
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Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls by Tsitkov, Stanislav, Valentine, Kelsey, Kozareva, Velina, Donde, Aneesh, Frank, Aaron, Lei, Susan, E. Van Eyk, Jennifer, Finkbeiner, Steve, Rothstein, Jeffrey D., Thompson, Leslie M., Sareen, Dhruv, Svendsen, Clive N., Fraenkel, Ernest

“…Amyotrophic Lateral Sclerosis (ALS), like many other neurodegenerative diseases, is highly heritable, but with only a small fraction of cases explained by…”
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Identifying patterns in amyotrophic lateral sclerosis progression from sparse longitudinal data by Ramamoorthy, Divya, Severson, Kristen, Ghosh, Soumya, Sachs, Karen, Glass, Jonathan D, Fournier, Christina N, Herrington, Todd M, Berry, James D, Ng, Kenney, Fraenkel, Ernest

“…The clinical presentation of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease, varies widely across patients, making it challenging to…”
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NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency by Matlock, Andrea D., Vaibhav, Vineet, Holewinski, Ronald, Venkatraman, Vidya, Dardov, Victoria, Manalo, Danica-Mae, Shelley, Brandon, Ornelas, Loren, Banuelos, Maria, Mandefro, Berhan, Escalante-Chong, Renan, Li, Jonathan, Finkbeiner, Steve, Fraenkel, Ernest, Rothstein, Jeffrey, Thompson, Leslie, Sareen, Dhruv, Svendsen, Clive N., Van Eyk, Jennifer E.

“…The National Institute of Health (NIH) Library of integrated network-based cellular signatures (LINCS) program is premised on the generation of a publicly…”
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